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anti-Paraoxonase 3 (PON3) Antibodies

PON3 is a member of the paraoxonase family and lies in a cluster on chromosome 7 with the other two family members. Additionally we are shipping Paraoxonase 3 Kits (14) and Paraoxonase 3 Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PON3 5446 Q15166
PON3 269823 Q62087
PON3 312086 Q68FP2
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Top anti-Paraoxonase 3 Antibodies at antibodies-online.com

Showing 10 out of 70 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC, WB WB Suggested Anti-PON3 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: NCI-H226 cell lysate Immunohistochemistry with Liver tissue at an antibody concentration of 5µg/ml using anti-PON3 antibody (ARP41833_P050) 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of PON3 Antibody (N-term) in HepG2 cell line lysates (35ug/lane). PON3 (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-PON3 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: COLO205 cell lysate WB Suggested Anti-PON3  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500  Positive Control: COLO205 cell lysate  PON3 is supported by BioGPS gene expression data to be expressed in COLO205 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), WB Anti-PON3 antibody IHC staining of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN958317 concentration 5 ug/ml. 50 μg Log in to see 8 to 10 Days
$676.50
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of PON3 Antibody (N-term) (ABIN652536) in HepG2 cell line lysates (35 µg/lane). PON3 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human hepatocarcinoma with PON3 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Goat Un-conjugated WB 100 μg Log in to see 8 to 10 Days
$969.83
Details
Human Mouse Un-conjugated IHC (p), WB Anti-PON3 antibody IHC staining of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN957769 dilution 1:400. 50 μL Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated WB PON3 antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 3 to 4 Days
$473.93
Details
Human Rabbit Un-conjugated WB PON3 antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 3 to 4 Days
$473.93
Details

PON3 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Paraoxonase 3 Antibodies

  1. Human Polyclonal PON3 Primary Antibody for EIA, WB - ABIN453785 : Precourt, Seidman, Delvin, Amre, Deslandres, Dominguez, Sinnett, Levy: Comparative expression analysis reveals differences in the regulation of intestinal paraoxonase family members. in The international journal of biochemistry & cell biology 2009 (PubMed)
    Show all 2 references for ABIN453785

  2. Human Polyclonal PON3 Primary Antibody for IHC, WB - ABIN2777017 : Sanghera, Manzi, Minster, Shaw, Kao, Bontempo, Kamboh: Genetic variation in the paraoxonase-3 (PON3) gene is associated with serum PON1 activity. in Annals of human genetics 2008 (PubMed)

More Antibodies against Paraoxonase 3 Interaction Partners

Cow (Bovine) Paraoxonase 3 (PON3) interaction partners

  1. The aim of this study was to evaluate expression of the natural anti-oxidants paraoxonase (PON) 1 (show PON1 Antibodies), 2 and 3 in granulosa cells and PON1 (show PON1 Antibodies) activity in follicular fluid and plasma of dairy cows.

Human Paraoxonase 3 (PON3) interaction partners

  1. PON3 SNP rs13226149 was associated with intracerebral hemorrhage in log-additive and dominant models. The A allele of rs13226149 contributed to the decreased risk of ICH (show COL4a2 Antibodies). SNP rs1053275 was not associated with ICH (show COL4a2 Antibodies).

  2. Data suggest cigarette smoke leads to inhibition of hydrolytic activity of paraoxonase isoenzymes (PON1 (show PON1 Antibodies), PON2 (show PON2 Antibodies), PON3) by modification of thiol groups, by interactions with free radicals/heavy metals, or by decreasing HDL (show HSD11B1 Antibodies) level in blood. [REVIEW]

  3. Interaction of PON-3 and PON-1 (show PON1 Antibodies) and HDL (show HSD11B1 Antibodies) are associated with the presence and severity of coronary artery disease in type 2 diabetes mellitus patients.

  4. PON3 in HDL (show HSD11B1 Antibodies) may be an important protein in preventing atherosclerosis.

  5. PON2 (show PON2 Antibodies) and PON3 (i) are associated with mitochondria and mitochondria-associated membranes, (ii) modulate mitochondria-dependent superoxide production, and (iii) prevent apoptosis.

  6. PON3 is upregulated in cancer tissues and protects against mitochondrial superoxide-mediated cell death.

  7. Our results suggest that low serum paraoxonase activity is a risk factor for Alzheimer disease. Furthermore, multiple variants in PON (show PON1 Antibodies) influence serum paraoxonase activity and their effects may be synergistic.

  8. Increased serum paraoxonase-3 concentration is associated with insulin (show INS Antibodies) sensitivity in peripheral artery disease and with inflammation in coronary artery disease.

  9. This study reports for the first time an important increase in serum PON3 concentrations in HIV-infected patients that is associated with their oxidative status and their treatment with NNRTI.

  10. investigation of whether gene silencing of Pon3 causes oxidative stress in cell line: Data suggest that PON3 knockdown reduces cell proliferation and total antioxidant capacity at ambient oxygen levels.

Mouse (Murine) Paraoxonase 3 (PON3) interaction partners

  1. study suggests a role for PON3 in the metabolism of lipid and bile acid as well as protection against atherosclerosis, gallstone disease, and obesity

  2. PON3 is upregulated in cancer tissues and protects against mitochondrial superoxide-mediated cell death.

  3. investigation of effect of knockout of Pon3 in embryo: Data suggest that Pon3-/- mice exhibit increased early embryonic and neonatal mortality.

  4. mouse Pon3 is expressed in a wide range of tissues, and that its expression is temporally controlled

  5. PON3 proteins were present in the vast majority of tissues investigated. mRNA for these proteins was also expressed in most of these tissues suggesting local production and the ability to respond in situ to inflammatory stimuli.

  6. The anti-atherogenic biological activities were studied in vitro using serum or cell cultures, and also in vivo, using PON 1 (show PON1 Antibodies)/2/3 knockout or transgenic mice, as well as humans - healthy volunteers and atherosclerotic patients.

  7. The directed evolution and characterization of recombinant variants of serum paraoxonase PON3, is described.

Rabbit Paraoxonase 3 (PON3) interaction partners

  1. The directed evolution and characterization of recombinant variants of serum paraoxonase PON3, is described.

Pig (Porcine) Paraoxonase 3 (PON3) interaction partners

  1. Results show that PON3 mRNA and protein are ubiquitously expressed in pig tissues. Moreover, the relative abundance of PON3 mRNA, measured in perirenal and subcutaneous fat tissues, is higher in obese gilts compared with the leaner (show CACNA1A Antibodies) gilts.

Paraoxonase 3 (PON3) Antigen Profile

Protein Summary

This gene is a member of the paraoxonase family and lies in a cluster on chromosome 7 with the other two family members. The encoded protein is secreted into the bloodstream and associates with high-density lipoprotein (HDL). The protein also rapidly hydrolyzes lactones and can inhibit the oxidation of low-density lipoprotein (LDL), a function that is believed to slow the initiation and progression of atherosclerosis. Alternatively spliced variants which encode different protein isoforms have been described\; however, only one has been fully characterized.

Gene names and symbols associated with anti-Paraoxonase 3 (PON3) Antibodies

  • paraoxonase 3 (PON3) antibody
  • paraoxonase 3 (Pon3) antibody
  • 2810004E20 antibody
  • AI786302 antibody

Protein level used designations for anti-Paraoxonase 3 (PON3) Antibodies

paraoxonase 3 , serum paraoxonase/lactonase 3-like , serum paraoxonase/lactonase 3 , paraoxanase-3

GENE ID SPECIES
699236 Macaca mulatta
100337686 Ovis aries
100408549 Callithrix jacchus
100436262 Pongo abelii
100603110 Nomascus leucogenys
463548 Pan troglodytes
510953 Bos taurus
5446 Homo sapiens
269823 Mus musculus
312086 Rattus norvegicus
100008754 Oryctolagus cuniculus
475235 Canis lupus familiaris
733674 Sus scrofa
100721546 Cavia porcellus
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