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anti-Parathyroid Hormone 1 Receptor (PTH1R) Antibodies

The protein encoded by PTH1R is a member of the G-protein coupled receptor family 2. Additionally we are shipping PTH1R Proteins (14) and PTH1R Kits (9) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PTH1R 5745 Q03431
PTH1R 19228 P41593
PTH1R 56813 P25961
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Top anti-PTH1R Antibodies at antibodies-online.com

Showing 10 out of 74 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IF, IHC, ELISA, WB Western blot analysis of extracts from Jurkat cells, using PTHR1 Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human brain tissue, using PTHR1 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Mouse Un-conjugated ICC, IHC, ELISA, WB Figure 1: Immunofluorescence analysis of SK-BR-3 cells using PTH1R mouse mAb (green) . Blue: DRAQ5 fluorescent DNA dye. Figure 2: Immunohistochemical analysis of paraffin-embedded human kidney tissues using PTH1R mouse mAb with DAB staining. 100 μL Log in to see 3 to 4 Days
$393.80
Details
Human Mouse Un-conjugated IHC (p), WB 0.1 mg Log in to see 10 to 12 Days
$554.40
Details
Human Rabbit Un-conjugated IHC (p) 7 mL Log in to see 2 to 3 Days
$237.00
Details
Human Mouse Un-conjugated IHC (p), WB Human Liver (formalin-fixed, paraffin-embedded) stained with PTHR1 antibody ABIN334275 at 5 ug/ml followed by biotinylated anti-mouse IgG secondary antibody ABIN481714, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated IF, IHC (p), ELISA, WB Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated ICC, IHC (p), WB Anti-Parathyroid Hormone Receptor 1 antibody, IHC(P) IHC(P): Human Thyroid Cancer Tissue 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Mouse Un-conjugated EIA, IF, IHC (p), WB 0.1 mL Log in to see 6 to 8 Days
$390.50
Details
Cow Mouse Un-conjugated IHC, WB 0.05 mg Log in to see 2 to 3 Days
$481.25
Details
Cow Rabbit Un-conjugated IC, IF, IHC, WB Immunofluorescent analysis of PTHR1 staining in HEK293T cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a hidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of PTHR1 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugad compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL Log in to see 9 Days
$487.50
Details

PTH1R Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , , , ,
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Mouse (Murine)
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Rat (Rattus)


Top referenced anti-PTH1R Antibodies

  1. Human Monoclonal PTH1R Primary Antibody for EIA, IF - ABIN1108787 : Dean, Vilardaga, Potts, Gardella: Altered selectivity of parathyroid hormone (PTH) and PTH-related protein (PTHrP) for distinct conformations of the PTH/PTHrP receptor. in Molecular endocrinology (Baltimore, Md.) 2007 (PubMed)
    Show all 2 references for ABIN1108787

  2. Human Monoclonal PTH1R Primary Antibody for ICC, IHC - ABIN969372 : Yang, Hoang, Kubo, Kawano, Chou, Sowers, Huvos, Meyers, Healey, Gorlick: Over-expression of parathyroid hormone Type 1 receptor confers an aggressive phenotype in osteosarcoma. in International journal of cancer. Journal international du cancer 2007 (PubMed)
    Show all 2 references for ABIN969372

  3. Human Polyclonal PTH1R Primary Antibody for IF, IHC - ABIN1535655 : Schipani, Karga, Karaplis, Potts, Kronenberg, Segre, Abou-Samra, Jüppner: Identical complementary deoxyribonucleic acids encode a human renal and bone parathyroid hormone (PTH)/PTH-related peptide receptor. in Endocrinology 1993 (PubMed)

More Antibodies against PTH1R Interaction Partners

Zebrafish Parathyroid Hormone 1 Receptor (PTH1R) interaction partners

  1. Loss of function of either PTHR1 or PTHrP (show PTHLH Antibodies) in zebrafish leads to a localized aortic defect that is Notch (show NOTCH1 Antibodies) dependent.

Human Parathyroid Hormone 1 Receptor (PTH1R) interaction partners

  1. A Homozygous [Cys25]PTH(1-84) Mutation That Impairs PTH/PTHrP Receptor Activation Defines a Novel Form of Hypoparathyroidism.

  2. Data suggest affinity of ligands for binding site on PTHR1, either in GTP-binding protein-dependent or -independent conformation, alters duration of action of ligand in target cells; ligands were fragments of PTHRP/parathyroid hormone-related protein (show PTHLH Antibodies).

  3. This Review discusses current understanding of PTHR1 modes of action and how these findings might be applied in future therapeutic agents--{REVIEW}

  4. We show that sustained stimulation with PTH (show PTH Antibodies) leads to diminished potentiation of carbachol-evoked Ca2 (show CA2 Antibodies)+ signals. This does not require internalization of PTH1R.

  5. data indicate that, albeit the similarity in its subcellular distribution, PTH1R in PDL cells exhibits characteristics different from those in MG63 cells, pointing to the cell type specificity of this receptor

  6. data significantly increase the number of presently known unique PFE-causing PTH1R mutations and provide a series of variants with unclear pathogenicity which will require further in vitro assaying to determine effects on protein structure and function

  7. Disruption of beta-catenin (show CTNNB1 Antibodies) binding to parathyroid hormone (PTH (show PTH Antibodies)) receptor PTH1R inhibits PTH (show PTH Antibodies)-stimulated ERK1/2 (show MAPK1/3 Antibodies) activation.

  8. PTHR1 signaling is important in maintaining osteosarcoma proliferation and undifferentiated state.

  9. salt bridge between Arg-20 on parathyroid hormone (PTH (show PTH Antibodies)) and Asp (show ASIP Antibodies)-137 on the PTH1 receptor is essential for full affinity.

  10. Treatment of recipient HEK (show EPHA3 Antibodies) 293a cells transiently expressing PTH1R with PTH (show PTH Antibodies)-myc (show MYC Antibodies) CM allowed the labeling of endosomal structures positive for Rab5 (show RAB5A Antibodies) and/or for beta-arrestin1 (show ARRB1 Antibodies).

Mouse (Murine) Parathyroid Hormone 1 Receptor (PTH1R) interaction partners

  1. we propose that PTH (show PTH Antibodies) has a direct effect on osteoblasts and osteoclasts, and that this effect is mediated through PTH1R, thus contributing to bone remodeling

  2. Ihh (show IHH Antibodies) and PTH1R signaling in limb mesenchyme are both essential to regulate proper development of digit structures, although they appear to use different mechanisms.

  3. cells expressing osterix (show SP7 Antibodies) are mesenchymal progenitors contributing to all relevant cell types during morphogenesis.

  4. PTH1R regulates systemic mineral ion homeostasis and induction of FGF23 (show FGF23 Antibodies).

  5. PTH1R is an important component of mechanical signal transduction in osteocytic MLO-Y4 cells.

  6. These studies reveal that PTH1R signaling in osteoblasts regulates cartilaginous growth plate for postnatal growth of bone.

  7. Cbfbeta (show CBFB Antibodies) functions in upregulating Ihh (show IHH Antibodies) expression to promoter chondrocyte proliferation and osteoblast differentiation, and inhibiting PPR expression to enhance chondrocyte differentiation.

  8. Osteocytic gp130 (show LRPPRC Antibodies) is required to maintain PTH1R expression in the osteoblast lineage, and for the stimulation of osteoblast differentiation that occurs in response to PTH (show PTH Antibodies).

  9. PTH (show PTH Antibodies) receptor signaling enhances bone resorption by directly regulating Rankl (show TNFSF11 Antibodies) gene expression in osteocytes.

  10. Data suggest that parathyroid hormone (PTH (show PTH Antibodies)) receptor signaling could enhance the therapeutic potential of the pathway.

Cow (Bovine) Parathyroid Hormone 1 Receptor (PTH1R) interaction partners

  1. The expression of the PTH/PTHrP receptor in dairy cows before and after parturition is reported.

Pig (Porcine) Parathyroid Hormone 1 Receptor (PTH1R) interaction partners

  1. This study reveals clear genetic-statistical evidence for a link of KRT8 (show KRT8 Antibodies), FAF1 (show FAF1 Antibodies) and PTH1R with some of leg weakness related traits in pigs.

  2. These findings reveal that direct ezrin interactions promote PTH1R apical localization and signaling in LLC-PK1 cells.

  3. PTHLH (show PTHLH Antibodies) and PTHR1 were evaluated as functional candidate genes for their effects on number and shape of teats in pigs

PTH1R Antigen Profile

Protein Summary

The protein encoded by this gene is a member of the G-protein coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis. Two transcript variants encoding the same protein have been found for this gene.

Gene names and symbols associated with PTH1R

  • parathyroid hormone 1 receptor a (pth1ra) antibody
  • parathyroid hormone 1 receptor (PTH1R) antibody
  • parathyroid hormone 1 receptor (Pth1r) antibody
  • PFE antibody
  • PPR antibody
  • PTH antibody
  • PTH1 antibody
  • Pthr antibody
  • Pthr1 antibody
  • PTHrel antibody
  • zPTH1R antibody

Protein level used designations for PTH1R

parathyroid hormone receptor 1 , parathyroid hormone/parathyroid hormone-related peptide receptor , parathyroid hormone 1 receptor , PTH/PTHr receptor , PTH/PTHrP type I receptor , PTH1 receptor , Parathyroid hormone/parathyroid hormone-related peptide receptor , parathyroid hormone/parathyroid hormone-related peptide receptor-like , parathyroid hormone/parathyroid hormone-related protein receptor , seven transmembrane helix receptor , PTH-related peptide receptor , PTH/PTHrP receptor , parathyroid hormone receptor-1 , parathyroid receptor

GENE ID SPECIES
30629 Danio rerio
420401 Gallus gallus
461008 Pan troglodytes
712147 Macaca mulatta
100054278 Equus caballus
100190839 Pongo abelii
100402780 Callithrix jacchus
5745 Homo sapiens
19228 Mus musculus
56813 Rattus norvegicus
507783 Bos taurus
403779 Canis lupus familiaris
397675 Sus scrofa
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