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anti-Parathyroid Hormone-Like Hormone (PTHLH) Antibodies

The protein encoded by PTHLH is a member of the parathyroid hormone family.

list all antibodies Gene Name GeneID UniProt
Anti-Human PTHLH PTHLH 5744 P12272
Anti-Rat PTHLH PTHLH 24695 P13085
Anti-Mouse PTHLH PTHLH 19227  
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More Antibodies against Parathyroid Hormone-Like Hormone Interaction Partners

Zebrafish Parathyroid Hormone-Like Hormone (PTHLH) interaction partners

  1. Loss of function of either PTHR1 (show PTH1R Antibodies) or PTHrP in zebrafish leads to a localized aortic defect that is Notch (show NOTCH1 Antibodies) dependent.

  2. In normal cartilage development, sox9 (show SOX9 Antibodies) upregulates pthlh, which downregulates runx2 (show RUNX2 Antibodies), and that the duplicated nature of all three of these genes in zebrafish creates a network of regulation by different co-orthologs in different tissues.

Human Parathyroid Hormone-Like Hormone (PTHLH) interaction partners

  1. TGF-beta (show TGFB1 Antibodies) and PTHrP were confirmed to be involved in regulating the malignant progression in breast cancer, and PTHrP expression, to be associated with bone metastasis as a potential prognostic marker in ER negative breast cancer

  2. Data suggest affinity of ligands for binding site on PTH1R/parathyroid hormone 1 receptor (show PTH1R Antibodies), either in GTP-binding protein-dependent or -independent conformation, alters duration of action of ligand in target cells; ligands were peptide fragments of PTHRP.

  3. A novel heterozygous mutation in PTHLH gene was identified in a Chinese pedigree with brachydactyly type E.

  4. PTHLH/PTHrP could play a role in the pathogenesis of oral squamous cell carcinoma by affecting cell proliferation and cell cycle.

  5. PTHrP regulates Caco-2 cell proliferation via several signaling pathways.

  6. Intermittent application of PTHrP represents an important novel means to improve chondrogenesis of MSCs and may be considered as a supporting clinical-treatment mode for MSC (show MSC Antibodies)-based cartilage defect regeneration

  7. Data show three individuals with duplications of the parathyroid hormone-like hormone (PTHLH) locus leading to a hitherto unrecognized syndrome characterized by acro (show ACR Antibodies)-osteolysis, cortical irregularity of long bones and metadiaphyseal enchondromata.

  8. PTHrP positively modulates cell cycle progression and changes the expression of proteins involved in cell cycle regulation.

  9. miR (show MLXIP Antibodies)-126-5p could directly target PTHrP and have a tumor suppressor function in giant cell tumor.

  10. High PTHLH expression is strongly associated with poor outcome both in overall survival and disease-free survival for patients who underwent standard nephrectomy.

Pig (Porcine) Parathyroid Hormone-Like Hormone (PTHLH) interaction partners

  1. PTHLH and PTHR1 (show PTH1R Antibodies) were evaluated as functional candidate genes for their effects on number and shape of teats in pigs

Cow (Bovine) Parathyroid Hormone-Like Hormone (PTHLH) interaction partners

  1. To investigate the roles of mammary PTHrP in calcium uptake and/or release in the mammary gland of cows, plasma PTHrP and Ca levels, and their arterial-venous differences were examined in a Jersey cow during the periparturient period.

Mouse (Murine) Parathyroid Hormone-Like Hormone (PTHLH) interaction partners

  1. the p27 (show CDKN1B Antibodies) pathway may function downstream in the action of PTHrP to regulate skeletal growth and development.

  2. Data demonstrate that the deletion of cyclin-dependent kinase inhibitor p27 (p27 (show CDKN1B Antibodies)) in parathyroid hormone like hormone (Pthrp) knock-in(KI/KI (show AXIN1 Antibodies)) mice can partially rescue defects in dental and mandibular development.

  3. The ventral signal observed from E12.5 on colocalized with motor neuron markers Isl1 (show ISL1 Antibodies)/2 and FoxP1 (show FOXP1 Antibodies) and The strong ventral signal colocalizing wtth Isl1 (show ISL1 Antibodies)/2 was observed in all rostrocaudal segments of the spinal cord.

  4. fluoride might be able to affect calcium homeostasis by regulating PTH (show PTH Antibodies), PTHrP, and CaSR (show CASR Antibodies)

  5. These results demonstrate that miR (show MLXIP Antibodies)-140 ensures the robustness of the PTHrP/HDAC4 (show HDAC5 Antibodies) regulatory system by suppressing MEF2C (show MEF2C Antibodies)-inducing stimuli.

  6. Integrin beta4 contributes to mammary gland development by sustaining PTHrP expression and enabling PTHrP signaling.

  7. PTHrP protects isolated cardiomyocytes from oxidative stress-induced (show SQSTM1 Antibodies) cell death.

  8. PDL- and Cer (show CBLN1 Antibodies)-induced CP resulted in increased production of the pancreatic BMP2 (show BMP2 Antibodies), apelin (show APLN Antibodies), and PTHrP signaling systems and that significant cross talk occurred among pancreatic BMP2 (show BMP2 Antibodies), apelin (show APLN Antibodies), and PTHrP

  9. results suggest that PrdxV is a key mediator contributing to the regulation of LPS/TLR4 (show TLR4 Antibodies)-induced immune responses

  10. Knockdown of CREB (show CREB1 Antibodies) or NFATc1 (show NFATC1 Antibodies) blocked PTHrP-induced RANKL (show TNFSF11 Antibodies) expression.

Goat Parathyroid Hormone-Like Hormone (PTHLH) interaction partners

  1. PTHrP overexpression protects goat mammary gland epithelial cells from CaSR (show CASR Antibodies) activation-induced apoptosis.

  2. Data show that signal transducer and activator of transcription 5a (Stat5a (show STAT5A Antibodies)) reduces the mRNA expression of parathyroid hormone-related protein (PTHrP) in mammary gland epithelial cells (GMECs).

Parathyroid Hormone-Like Hormone (PTHLH) Antigen Profile

Protein Summary

The protein encoded by this gene is a member of the parathyroid hormone family. This hormone regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. This hormone is involved in lactation possibly by regulating the mobilization and transfer of calcium to the milk. The receptor of this hormone, PTHR1, is responsible for most cases of humoral hypercalcemia of malignancy. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed. There is also evidence for alternative translation initiation from non-AUG (CUG and GUG) start sites, in-frame and downstream of the initiator AUG codon, to give rise to nuclear forms of this hormone.

Gene names and symbols associated with PTHLH

  • parathyroid hormone-like hormone (PTHLH) antibody
  • parathyroid hormone-like hormone a (pthlha) antibody
  • parathyroid hormone-like hormone (LOC100230763) antibody
  • parathyroid hormone-related protein (PTHrP) antibody
  • parathyroid hormone (Pth) antibody
  • parathyroid hormone-like hormone (pthlh) antibody
  • parathyroid hormone-like hormone (Pthlh) antibody
  • parathyroid hormone-like peptide (Pthlh) antibody
  • parathyroid hormone-like protein (PTHRP) antibody
  • parathyroid hormone-related peptide (PTH-RP) antibody
  • peroxiredoxin 5 (Prdx5) antibody
  • AOEB166 antibody
  • AOPP antibody
  • BDE2 antibody
  • HHM antibody
  • PLP antibody
  • Pmp20 antibody
  • Prdx6 antibody
  • PrxV antibody
  • PTH-like antibody
  • pthlh antibody
  • PTHR antibody
  • Pthrp antibody
  • si:ch211-286m4.5 antibody

Protein level used designations for PTHLH

parathyroid hormone-like hormone , parathyroid hormone-related protein , PTH-rP , PTH-related protein , osteostatin , parathyroid hormone-like related protein , parathyroid hormone related protein , PTHrP , parathyroid hormone-like peptide , parathyroid hormone-like protein , parathyroid-like peptide , parathyroid hormone-related peptide , PLP , PTH-related peptide , Parathyroid hormone-related protein , antioxidant enzyme B166 , liver tissue 2D-page spot 2D-0014IV , peroxiredoxin 6 , peroxiredoxin V , peroxiredoxin-5, mitochondrial , peroxisomal antioxidant enzyme , peroxisomal membrane protein 20 , prx-V , thioredoxin peroxidase PMP20 , thioredoxin reductase

473393 Pan troglodytes
554221 Danio rerio
710295 Macaca mulatta
100230763 Taeniopygia guttata
554222 Felis catus
100713626 Cavia porcellus
5744 Homo sapiens
100462910 Xenopus laevis
396281 Gallus gallus
403987 Canis lupus familiaris
396951 Sus scrofa
286767 Bos taurus
100009357 Oryctolagus cuniculus
24695 Rattus norvegicus
100033979 Equus caballus
100716151 Cavia porcellus
19227 Mus musculus
100860907 Capra hircus
443135 Ovis aries
54683 Mus musculus
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