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Parvin, beta Proteins (PARVB)

PARVB encodes a member of the parvin family of actin-binding proteins, which play a role in cytoskeleton organization and cell adhesion. Additionally we are shipping Parvin, beta Antibodies (26) and Parvin, beta Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PARVB 29780 Q9HBI1
PARVB 170736 Q9ES46
Rat PARVB PARVB 362973  
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Top Parvin, beta Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

PARVB Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for Parvin, beta (PARVB) Interaction Partners

Human Parvin, beta (PARVB) interaction partners

  1. PARVB protein

  2. Protein expression of beta-Parvin increases with colorectal cancer progression.

  3. Taken together, our results indicate that 24-MCF treatment increases parvin-beta expression, which may inhibit ILK (show ILK Proteins) downstream signaling.

  4. study found polymorphisms of rs5764455 and rs6006473 in PARVB gene in the Han Chinese population, and these polymorphisms were associated with the occurrence and progression of NAFLD.

  5. Our results suggested that variations, including insertion/deletions, in PARVB, as well as those in PNPLA3, are important in the progression of NAFLD.

  6. PARVB overexpression is a candidate biomarker for endophytic tumours and metastasis.

  7. PARVB plays a potential role in the pathogenesis of coronary restenosis.

  8. Polymorphisms in the SAMM50 and PARVB genes in addition to those in the PNPLA3 gene were observed to be associated with the development and progression of NAFLD.

  9. alpha-parvin (show PARVA Proteins), beta-parvin and migfilin (show FBLIM1 Proteins) were expressed in tumor cells in 53%, 2%, 28% and 53% of effusions and 57%, 20%, 83% and 25% of solid lesions, respectively.

  10. proper localization of beta-parvin to focal adhesions requires both the paxillin (show PXN Proteins) and integrin-linked kinase (show ILK Proteins) binding sites and that paxillin (show PXN Proteins) is important for early targeting of beta-parvin.

Mouse (Murine) Parvin, beta (PARVB) interaction partners

  1. Data from functional molecular imaging demonstrated that beta-parvin plays a regulatory role in the ILK (show ILK Proteins)-mediated Akt (show AKT1 Proteins) (also called protein kinase B (show AKT1 Proteins)) signaling cascades, suggesting that beta-parvin might be a crucial modulator of cell survival.

  2. Data show that affixin is a dysferlin binding protein that colocalizes with dysferlin at the sarcolemma of normal skeletal muscle.

Parvin, beta (PARVB) Protein Profile

Protein Summary

This gene encodes a member of the parvin family of actin-binding proteins, which play a role in cytoskeleton organization and cell adhesion. These proteins are associated with focal contacts and contain calponin homology domains that bind to actin filaments. This family member binds to alphaPIX and alpha-actinin, and it can inhibit the activity of integrin-linked kinase. This protein also functions in tumor suppression. Alternative splicing of this gene results in multiple transcript variants.

Gene names and symbols associated with Parvin, beta Proteins (PARVB)

  • parvin, beta (parvb)
  • parvin, beta (PARVB)
  • parvin, beta (Parvb)
  • affixin protein
  • AI595373 protein
  • AW742462 protein
  • beta-parvin protein
  • CGI-56 protein
  • D15Gsk1 protein
  • fd02e01 protein
  • wu:fd02e01 protein
  • zgc:73117 protein

Protein level used designations for Parvin, beta Proteins (PARVB)

parvin, beta , affixin , beta-parvin

GENE ID SPECIES
448070 Xenopus (Silurana) tropicalis
100011113 Monodelphis domestica
100556835 Anolis carolinensis
325686 Danio rerio
734573 Xenopus laevis
418235 Gallus gallus
29780 Homo sapiens
481215 Canis lupus familiaris
616294 Bos taurus
170736 Mus musculus
362973 Rattus norvegicus
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