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anti-Patatin-Like phospholipase Domain Containing 2 (PNPLA2) Antibodies

PNPLA2 encodes an enzyme which catalyzes the first step in the hydrolysis of triglycerides in adipose tissue. Additionally we are shipping Patatin-Like phospholipase Domain Containing 2 Kits (36) and Patatin-Like phospholipase Domain Containing 2 Proteins (9) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PNPLA2 57104 Q96AD5
PNPLA2 66853 Q8BJ56
PNPLA2 361676 P0C548
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Top anti-Patatin-Like phospholipase Domain Containing 2 Antibodies at antibodies-online.com

Showing 10 out of 156 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Goat Un-conjugated IHC, ELISA, WB ABIN190844 (0.5µg/ml) staining of Human Adipose lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Cow Goat Un-conjugated IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Mouse Un-conjugated EIA, IHC (p), WB 0.1 mL Log in to see 6 to 8 Days
$412.50
Details
Human Goat Un-conjugated ELISA, WB ABIN334463 (0.03µg/ml) staining of Human Heart lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Goat Un-conjugated EIA, WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Goat Un-conjugated EIA, IHC (p) 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated IP, IHC, WB Western blot analysis of ATGL expression in rat kidney tissue lysate. 100 μg Log in to see 2 to 3 Days
$283.50
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Goat Un-conjugated EIA, WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Goat Un-conjugated IHC, ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details

PNPLA2 Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-Patatin-Like phospholipase Domain Containing 2 Antibodies

  1. Human Monoclonal PNPLA2 Primary Antibody for EIA, IHC (p) - ABIN356228 : Fischer, Lefèvre, Morava, Mussini, Laforêt, Negre-Salvayre, Lathrop, Salvayre: The gene encoding adipose triglyceride lipase (PNPLA2) is mutated in neutral lipid storage disease with myopathy. in Nature genetics 2006 (PubMed)
    Show all 3 references for ABIN356228

  2. Human Polyclonal PNPLA2 Primary Antibody for IHC, ELISA - ABIN190844 : Schoenborn, Heid, Vollmert, Lingenhel, Adams, Hopkins, Illig, Zimmermann, Zechner, Hunt, Kronenberg: The ATGL gene is associated with free fatty acids, triglycerides, and type 2 diabetes. in Diabetes 2006 (PubMed)

  3. Human Polyclonal PNPLA2 Primary Antibody for ELISA, WB - ABIN334463 : Steinberg, Kemp, Watt: Adipocyte triglyceride lipase expression in human obesity. in American journal of physiology. Endocrinology and metabolism 2007 (PubMed)

More Antibodies against Patatin-Like phospholipase Domain Containing 2 Interaction Partners

Goat Patatin-Like phospholipase Domain Containing 2 (PNPLA2) interaction partners

  1. the ATGL gene plays an important role in triglyceride lipolysis in GMECs; ATGL may be involved in lipid metabolism during lactation

Human Patatin-Like phospholipase Domain Containing 2 (PNPLA2) interaction partners

  1. Data indicate that a tumor suppressor mechanism by which G0/G1 switch gene 2 (show G0S2 Antibodies) product (G0S2 (show G0S2 Antibodies)) directly inhibits activity of a key intracellular adipose triglyceride lipase (ATGL).

  2. Authors show that rat ATGL, coactivated by rat CGI-58 (show ABHD5 Antibodies), efficiently hydrolyzes triglycerides and retinyl ester.

  3. PNPLA2 mutations were associated with an extended phenotype, including brain involvement in cases of neutral lipid-storage disease with myopathy.

  4. Distinct cardiac phenotype between two homozygotes born in a village with accumulation of a genetic deficiency of adipose triglyceride lipase.

  5. ANGPTL8 is a stress-response protein that down-regulates expression of ATGL.

  6. Study reports the clinical and genetic findings of a neutral lipid storage disease with myopathy family of Italian origin with 3 affected siblings. to highlight the effect that different gene mutations may have on ATGL lipase (show LIPG Antibodies) activity, authors performed a functional characterization of the novel PNPLA2 missense mutations identified in their patients

  7. PLIN5 (show PLIN5 Antibodies) was significantly colocated with ATGL, mitochondria and CGI-58 (show ABHD5 Antibodies), indicating a close association between the key lipolytic effectors in resting skeletal muscle.

  8. PEDF (show SERPINF1 Antibodies) receptor is a transmembrane phospholipase that is required for the survival and antiapoptotic effects of PEDF (show SERPINF1 Antibodies) on retina cells. It has determinants for PEDF (show SERPINF1 Antibodies) binding within its L4 ectodomain that are critical for enzymatic stimulation.

  9. Data suggest that PNPLA2 hydrolyzes arachidonic acid from triglycerides in mast cell (MC) lipid droplets; PNPLA2 appears to regulate substrate availability of AA for eicosanoid (PGD2/LTC4) generation/secretion upon MC activation with IgE.

  10. Data suggest that pigment epithelium-derived factor (PEDF (show SERPINF1 Antibodies)) and adipose triglyceride lipase (ATGL) may serve as therapeutic targets for managing vascular hyperpermeability in sepsis.

Mouse (Murine) Patatin-Like phospholipase Domain Containing 2 (PNPLA2) interaction partners

  1. ANGPTL8 is a stress-response protein that down-regulates expression of ATGL.

  2. ATGL KO mice had significantly lower fasting plasma free fatty-acids compared to WT. Fasting endogenous glucose production and peripheral glucose metabolism were similar in KO and WT mice.

  3. Pharmacological inhibition of ATGL may prove useful to prevent HFD-induced obesity and insulin (show INS Antibodies) resistance

  4. A role for Atgl in kidney lipolysis:fasting up-regulates Atgl levels and phosphorylation in mouse kidney.

  5. data provide mechanistic insights into Jordans' anomaly in neutrophils and suggest that ATGL is a potent regulator of immune cell function and inflammatory diseases.

  6. Data show that obese adipocyte-specific adipose triglyceride lipase (ATGL) knockout (AAKO) mice had reduced adipocyte lipolysis.

  7. transcriptional transactivation assays with a luciferase reporter system revealed that Fabps enhance the ability of Atgl/Cgi-58 (show ABHD5 Antibodies)-mediated lipolysis to induce the activity of peroxisome proliferator-activated receptors.

  8. Data (including data from studies in atherosclerotic knockout mice) suggest CGI58- (abhydrolase domain containing 5 (show ABHD5 Antibodies)-)deficient macrophages store-up triglyceride droplets and have reduced phagocytic capacity, comparable to Atgl-deficient macrophages.

  9. Data suggest that cardiotrophin-1 (show CTF1 Antibodies) up-regulates lipolysis in white adipocytes via 1) induction of perilipin (show PLIN1 Antibodies), 2) activation of hormone sensitive lipase (show LIPE Antibodies) (via phosphorylation by PKA), and 3) inactivation of ATGL (via up-regulation of its inhibitor G0S2 (show G0S2 Antibodies)).

  10. 4E-BP1 (show EIF4EBP1 Antibodies)/2-null cells express less ATGL and accumulate more fat than control cells, while knock down of Egr1 (show EGR1 Antibodies) in 4E-BP1 (show EIF4EBP1 Antibodies)/2-null cells increases ATGL expression and decreases fat storage.

Pig (Porcine) Patatin-Like phospholipase Domain Containing 2 (PNPLA2) interaction partners

  1. Resveratrol activated sirtuin 1 (Sirt1 (show SIRT1 Antibodies)) gene expression and increased adipose triglyceride lipase (ATGL) gene expression and glycerol release. Furthermore, this study found the opposite Sirt1 (show SIRT1 Antibodies) regulation pattern for PPARgamma (show PPARG Antibodies) to that of ATGL in adipocytes.

  2. analysis of porcine adipose triglyceride lipase (PNPLA2) gene

  3. JAK (show JAK3 Antibodies)-STAT (show STAT1 Antibodies) and MAPK (show MAPK1 Antibodies) signaling pathways, as well as PPAR gamma (show PPARG Antibodies) all played important roles in the ATGL expression mediated by leptin (show LEP Antibodies)

  4. patatin-like phospholipase domain containing 2 gene (PNPLA2) is assiged to chromosome 2 in pigs.

  5. ATGL expression reacts to hormonal stimuli and plays a role in catecholamine-induced lipolysis in porcine adipose tissue.

Cow (Bovine) Patatin-Like phospholipase Domain Containing 2 (PNPLA2) interaction partners

  1. Tissue distribution of ATGL gene expression was highest in fat and muscle (skeletal and cardiac) tissue, while protein expression was solely detectible in the adipose tissue.

Patatin-Like phospholipase Domain Containing 2 (PNPLA2) Antigen Profile

Protein Summary

This gene encodes an enzyme which catalyzes the first step in the hydrolysis of triglycerides in adipose tissue. Mutations in this gene are associated with neutral lipid storage disease with myopathy.

Gene names and symbols associated with PNPLA2

  • patatin-like phospholipase domain containing 3 (pnpla3) antibody
  • patatin-like phospholipase domain containing 2 (PNPLA2) antibody
  • patatin-like phospholipase domain containing 2 (pnpla2) antibody
  • adipose triglyceride lipase (ATGL) antibody
  • patatin-like phospholipase domain containing 2 (Pnpla2) antibody
  • 0610039C21Rik antibody
  • 1110001C14Rik antibody
  • Atgl antibody
  • iPLA2zeta antibody
  • PEDF-R antibody
  • pnpla2 antibody
  • RGD1309044 antibody
  • TTS-2.2 antibody
  • TTS2 antibody
  • zgc:92195 antibody

Protein level used designations for PNPLA2

patatin-like phospholipase domain-containing protein 2 , patatin-like phospholipase domain containing 2 , adipose triglyceride lipase , IPLA2-zeta , TTS2.2 , calcium-independent phospholipase A2 , desnutrin , patatin-like phospholipase domain containing protein 2 , pigment epithelium-derived factor , transport-secretion protein 2.2 , triglyceride hydrolase , transport-secretion protein , PNPLA2/ATGL

GENE ID SPECIES
436610 Danio rerio
611403 Canis lupus familiaris
780152 Xenopus (Silurana) tropicalis
100219060 Taeniopygia guttata
100294555 Meleagris gallopavo
100860889 Capra hircus
57104 Homo sapiens
66853 Mus musculus
100049704 Sus scrofa
508493 Bos taurus
431066 Gallus gallus
361676 Rattus norvegicus
Selected quality suppliers for anti-Patatin-Like phospholipase Domain Containing 2 (PNPLA2) Antibodies
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