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anti-Patatin-Like phospholipase Domain Containing 3 (PNPLA3) Antibodies

The protein encoded by PNPLA3 is a triacylglycerol lipase that mediates triacylglycerol hydrolysis in adipocytes. Additionally we are shipping PNPLA3 Kits (12) and PNPLA3 Proteins (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PNPLA3 80339 Q9NST1
PNPLA3 116939 Q91WW7
PNPLA3 362972  
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Top anti-PNPLA3 Antibodies at antibodies-online.com

Showing 10 out of 90 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC, WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis in K562 cell line lysates (35ug/lane) using PNPLA3 Antibody (N-term) Cat.-No AP53370PU-N. This demonstrates the PNPLA3 antibody detected the PNPLA3 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$401.50
Details
Dog Goat Un-conjugated EIA, IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Goat Un-conjugated IHC, ELISA, WB   100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Rabbit Un-conjugated WB PNPLA3 Antibody (N-term)  western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the PNPLA3 antibody detected the PNPLA3 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Goat Un-conjugated IHC (p), ELISA, WB 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated IHC, WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Mouse Rabbit Un-conjugated WB Mouse Pnpla3 Antibody (C-term)  western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the Pnpla3 antibody detected the Pnpla3 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC, ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details

PNPLA3 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Rat (Rattus)
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Top referenced anti-PNPLA3 Antibodies

  1. Human Polyclonal PNPLA3 Primary Antibody for EIA, WB - ABIN954228 : Santoro, Kursawe, DAdamo, Dykas, Zhang, Bale, Calí, Narayan, Shaw, Pierpont, Savoye, Lartaud, Eldrich, Cushman, Zhao, Shulman, Caprio: A common variant in the patatin-like phospholipase 3 gene (PNPLA3) is associated with fatty liver disease in obese children and adolescents. in Hepatology (Baltimore, Md.) 2010 (PubMed)
    Show all 3 references for ABIN954228

  2. Human Polyclonal PNPLA3 Primary Antibody for IHC, ELISA - ABIN361184 : Kumari, Schoiswohl, Chitraju, Paar, Cornaciu, Rangrez, Wongsiriroj, Nagy, Ivanova, Scott, Knittelfelder, Rechberger, Birner-Gruenberger, Eder, Brown, Haemmerle, Oberer, Lass, Kershaw, Zimmermann et al.: Adiponutrin functions as a nutritionally regulated lysophosphatidic acid acyltransferase. ... in Cell metabolism 2012 (PubMed)
    Show all 2 references for ABIN361184

  3. Dog (Canine) Polyclonal PNPLA3 Primary Antibody for EIA, IHC (p) - ABIN375148 : Steinberg, Kemp, Watt: Adipocyte triglyceride lipase expression in human obesity. in American journal of physiology. Endocrinology and metabolism 2007 (PubMed)

  4. Human Polyclonal PNPLA3 Primary Antibody for IHC, WB - ABIN2783569 : Wilson, Gardner, Lambie, Commans, Crowther: Characterization of the human patatin-like phospholipase family. in Journal of lipid research 2006 (PubMed)

More Antibodies against PNPLA3 Interaction Partners

Human Patatin-Like phospholipase Domain Containing 3 (PNPLA3) interaction partners

  1. transmembrane 6 superfamily 2 C/T or T/T variants in conjunction with patatin-like phospho-lipase (show LIPG Antibodies) domain-containing protein 3 (show HSPB3 Antibodies) G/G variants may be potential genetic risk factors for developing HCC (show FAM126A Antibodies) in alcohol-related cirrhosis.

  2. Steatosis severity was independently associated with PNPLA3 rs738409 in large cohort of patients with genotype 1 Chronic hepatitis C.

  3. I148M variant in PNPLA3 reduces central adiposity and metabolic disease risks while increasing Nonalcoholic fatty liver disease.

  4. PNPLA3 148M Carriers with Inflammatory Bowel Diseases Have Higher Susceptibility to Hepatic Steatosis and Higher Liver Enzymes.

  5. PNPLA3 rs738409 polymorphism was associated with the severity of liver fibrosis in patients coinfected with HIV and hepatitis C virus.

  6. Letter: PNPLA3 I148M affects de novo NAFLD (show TSC2 Antibodies) occurrence with a prominent interaction with obesity in liver transplant recipients.

  7. PNPLA3 polymorphism is associated with Hepatocellular Carcinoma Development in Non-Viral Chronic Liver Diseases.

  8. This study investigates the association between PNPLA3 rs738409 with health services utilization in a general population. PNPLA3 rs738409 was associated with the number of outpatient visits, hospitalization, and inpatient days.

  9. Treating liver fat and serum triglyceride levels in NAFLD, effects of PNPLA3 and TM6SF2 genotypes: effect of Omacor administration.

  10. As the HepG2 cell line harbors the I148M mutation in homozygous state it is hypothesized that this should represent an ideal model system for PNPLA3 biology.

Mouse (Murine) Patatin-Like phospholipase Domain Containing 3 (PNPLA3) interaction partners

  1. Neither ablation nor overexpression of wild-type PNPLA3 affects liver fat content in mice, whereas hepatic overexpression of the human 148M transgene causes steatosis.

  2. PNPLA3 plays a role in remodeling TAG in lipid droplets, as they accumulate in response to food intake

  3. adiponutrin/PNPLA3 is regulated by two key factors of the glycolytic and lipogenic pathways, raising the question of its implication in the metabolism of carbohydrates and lipids

  4. data argue against a role for Pnpla3 loss-of-function in fatty liver disease or metabolic syndrome in mice.

  5. Loss of Pnpla3 does not cause fatty liver, liver enzyme elevation, or insulin (show INS Antibodies) resistance in mice.

  6. Microarray-based gene profiling showed that the expression level of PNPLA3 in hepatocytes is correlated with that of genes associated with the lipogenic pathway such as ME1 (show ME1 Antibodies), SPOT14 (show THRSP Antibodies), and SCD1 (show SCD Antibodies).

  7. data suggest that murine ATGL (show PNPLA2 Antibodies) but not adiponutrin contributes to net adipocyte lipolysis and that ATGL (show PNPLA2 Antibodies) and adiponutrin are oppositely regulated by insulin (show INS Antibodies) both in vitro and in vivo

PNPLA3 Antigen Profile

Protein Summary

The protein encoded by this gene is a triacylglycerol lipase that mediates triacylglycerol hydrolysis in adipocytes. The encoded protein, which appears to be membrane bound, may be involved in the balance of energy usage/storage in adipocytes.

Gene names and symbols associated with PNPLA3

  • patatin-like phospholipase domain containing 3 (PNPLA3) antibody
  • patatin-like phospholipase domain containing 3 (Pnpla3) antibody
  • Adpn antibody
  • C22orf20 antibody
  • iPLA(2)epsilon antibody

Protein level used designations for PNPLA3

acylglycerol O-acyltransferase , adiponutrin , calcium-independent phospholipase A2-epsilon , iPLA2-epsilon , iPLA2epsilon , patatin-like phospholipase domain-containing protein 3

GENE ID SPECIES
80339 Homo sapiens
116939 Mus musculus
362972 Rattus norvegicus
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