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anti-Patatin-Like phospholipase Domain Containing 6 (PNPLA6) Antibodies

PNPLA6 encodes a phospholipase that deacetylates intracellular phosphatidylcholine to produce glycerophosphocholine. Additionally we are shipping Patatin-Like phospholipase Domain Containing 6 Kits (7) and Patatin-Like phospholipase Domain Containing 6 Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PNPLA6 4907 P21589
PNPLA6 50767 Q3TRM4
PNPLA6 360753  
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Top anti-Patatin-Like phospholipase Domain Containing 6 Antibodies at antibodies-online.com

Showing 10 out of 67 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of NTE Antibody (C-term) in HepG2 cell line lysates (35ug/lane).This demonstrates the NTE antibody detected the PNPLA6 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated ELISA, WB   100 μg Log in to see 2 to 3 Days
$302.50
Details
Zebrafish Rabbit Un-conjugated IHC (fro), IHC (p), WB Western blot: PNPLA6 Polyclonal Antibody 0.1 mg Log in to see 6 to 8 Days
$313.50
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB PNPLA6 Antibody (C-term)  western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the PNPLA6 antibody detected the PNPLA6 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB Western blot analysis of PNPLA6 expression in SHSY5Y (A) whole cell lysates. 200 μL Log in to see 9 Days
$487.50
Details
Mouse Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Goat Un-conjugated ELISA, WB   0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Fish Rabbit Un-conjugated IHC (fro), IHC (p), WB 100 μg Log in to see 8 to 10 Days
$449.17
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 14 Days
$201.19
Details

PNPLA6 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Patatin-Like phospholipase Domain Containing 6 Antibodies

  1. Human Polyclonal PNPLA6 Primary Antibody for EIA, WB - ABIN953768 : Hein, Rainier, Richardson, Fink: Motor neuron disease due to neuropathy target esterase mutation: enzyme analysis of fibroblasts from human subjects yields insights into pathogenesis. in Toxicology letters 2010 (PubMed)
    Show all 4 references for ABIN953768

  2. Human Polyclonal PNPLA6 Primary Antibody for ELISA, WB - ABIN1451394 : Grimwood, Gordon, Olsen, Terry, Schmutz, Lamerdin, Hellsten, Goodstein, Couronne, Tran-Gyamfi, Aerts, Altherr, Ashworth, Bajorek, Black, Branscomb, Caenepeel, Carrano, Caoile, Chan, Christensen et al.: The DNA sequence and biology of human chromosome 19. ... in Nature 2004 (PubMed)

More Antibodies against Patatin-Like phospholipase Domain Containing 6 Interaction Partners

Fruit Fly (Drosophila melanogaster) Patatin-Like phospholipase Domain Containing 6 (PNPLA6) interaction partners

  1. inducible, neuron-specific expression of full-length human wildtype NTE reduces vacuole formation and substantially rescues mobility.

  2. OP-modified SWS cannot release PKA-C3 and the resulting loss of PKA-C3 activity plays a crucial role in developing the delayed symptoms of organophosphate-induced delayed neuropathy but not in the acute toxicity

Human Patatin-Like phospholipase Domain Containing 6 (PNPLA6) interaction partners

  1. CD73 promotes the growth of human colorectal cancer cells through EGFR (show EGFR Antibodies) and the b-catenin/cyclin D1 (show CCND1 Antibodies) signaling pathway. CD73 may be used as a valuable biomarker of colorectal cancer.

  2. The NT5E (show NT5E Antibodies) gene is involved in both intrinsic and acquired resistance to platinum-based drugs in ovarian cancer. [meta-analysis]

  3. report on a Chinese family with CALJA and novel compound heterozygous mutations (c.1360G>A (p.Gly454Arg) and c.1387C>T (p.Arg463X)) in NT5E (show NT5E Antibodies)

  4. inducible, neuron-specific expression of full-length human wildtype NTE reduces vacuole formation and substantially rescues mobility.

  5. Eight mutations in six families with Oliver-McFarlane or Laurence-Moon syndrome were identified in the PNPLA6 gene, which encodes neuropathy target esterase.

  6. role of CD73 and CD39 (show ENTPD1 Antibodies) ectonucleotidases in T cell differentiation

  7. PNPLA6 has a role in photoreceptor survival; its mutations are linked to photoreceptor degeneration and various forms of childhood blindness

  8. Expression of NPP1 (show ENPP1 Antibodies) and 5'-nucleotidase (show NT5E Antibodies) by valve interstitial cells promotes the mineralization of the aortic valve through A2aR (show ADORA2A Antibodies) and a cAMP/PKA/CREB (show CREB1 Antibodies) pathway.

  9. we found a novel compound heterozygous mutation and a novel homozygous one in the PNPLA6 gene in two Japanese patients with BNS.

  10. Data confirm PNPLA6 mutations as the leading cause of Boucher-Neuhauser syndrome and suggest inquiring about a history of hypogonadism or visual changes in patients presenting with late-onset gait ataxia (show USP14 Antibodies).

Mouse (Murine) Patatin-Like phospholipase Domain Containing 6 (PNPLA6) interaction partners

  1. the expression of CaMKIIalpha (show CAMK2 Antibodies) and pCREB exhibits a significant increase in cortex and hippocampus after treatment with PFOS, compared with the control.

  2. NTE has a role in neural development and in the neurodegeneration induced by organophosphate compounds in mice

  3. mouse brain neuropathy target esterase is a lysophospholipase (show ASPG Antibodies)

  4. impairment of vasculogenesis in the yolk sacs and embryos of null mutant conceptuses suggested that NTE is required for normal blood vessel development

  5. Increase of neuropathy target esterase (NTE) expression contributes to increased production and accumulation of glycerophosphocholine in mammalian renal cells in tissue culture and in vivo.

  6. We conclude that spongiform pathology in conditional NTE knockout mice is not mediated by PrPc (show PRNP Antibodies), and that tubulovesicular inclusions can be seen in spongiform encephalopathy of other etiologies and are not pathognomonic of prion (show PRNP Antibodies) disease

Patatin-Like phospholipase Domain Containing 6 (PNPLA6) Antigen Profile

Protein Summary

This gene encodes a phospholipase that deacetylates intracellular phosphatidylcholine to produce glycerophosphocholine. It is thought to function in neurite outgrowth and process elongation during neuronal differentiation. The protein is anchored to the cytoplasmic face of the endoplasmic reticulum in both neurons and non-neuronal cells. Mutations in this gene result in autosomal recessive spastic paraplegia, and the protein is the target for neurodegeneration induced by organophosphorus compounds and chemical warfare agents. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with PNPLA6

  • swiss cheese (sws) antibody
  • 5'-nucleotidase, ecto (CD73) (NT5E) antibody
  • patatin-like phospholipase domain containing 6 (pnpla6) antibody
  • patatin-like phospholipase domain containing 6 (PNPLA6) antibody
  • patatin-like phospholipase domain containing 6 (Pnpla6) antibody
  • AI661849 antibody
  • CALJA antibody
  • CD73 antibody
  • CG2212 antibody
  • Dmel\\CG2212 antibody
  • E5NT antibody
  • eN antibody
  • eNT antibody
  • iPLA2delta antibody
  • MSws antibody
  • NT antibody
  • NT5 antibody
  • Nte antibody
  • NTEMND antibody
  • olfE antibody
  • RGD1564611 antibody
  • SPG39 antibody
  • sws antibody
  • wu:fy20f06 antibody

Protein level used designations for PNPLA6

CG2212-PA , CG2212-PB , CG2212-PC , olfactory E , olfactory-E , swiss-cheese , swisscheese , sws-PA , sws-PB , sws-PC , 5'-NT , 5'-nucleotidase , Purine 5-Prime-Nucleotidase , ecto-5'-nucleotidase , nte , neuropathy target esterase , patatin-like phospholipase domain-containing protein 6 , Swiss cheese , Swiss-cheese

GENE ID SPECIES
31716 Drosophila melanogaster
4907 Homo sapiens
386860 Danio rerio
10908 Homo sapiens
50767 Mus musculus
425396 Gallus gallus
484993 Canis lupus familiaris
100524423 Sus scrofa
767822 Bos taurus
360753 Rattus norvegicus
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