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PNPLA8 encodes a member of the patatin-like phospholipase domain containing protein family. Additionally we are shipping Patatin-Like phospholipase Domain Containing 8 Antibodies (36) and Patatin-Like phospholipase Domain Containing 8 Proteins (3) and many more products for this protein.
iPLA2gamma plays an important role in in vivo Thromboxane A2 production accompanied by thrombus formation.
iPLA2gamma plays a cardioprotective role during the acute stage of Chagas' disease.
Thus, complement-mediated activation of iPLA(2)gamma is mediated via ERK (show EPHB2 ELISA Kits) and p38 (show CRK ELISA Kits) pathways, and phosphorylation of Ser (show SIGLEC1 ELISA Kits)-511 and/or Ser (show SIGLEC1 ELISA Kits)-515 plays a key role in the catalytic activity and signaling of iPLA(2)gamma.
These results suggest distinct roles for iPLA2beta (show PLA2G6 ELISA Kits) and iPLA2gamma in cellular homeostasis and signaling, a functional link between peroxisomal AA release and eicosanoid generation, and a potential contribution of iPLA2gamma to tumorigenesis.
iPLA2 (show PLA2G6 ELISA Kits) activation is not sufficient for SOCE activation. iPLA2 (show PLA2G6 ELISA Kits) may regulate basal phosphoinositide metabolism
UCP2 (show UCP2 ELISA Kits), functional due to fatty acids released by redox-activated mt-iPLA2gamma, suppresses mitochondrial superoxide production by its uncoupling action.
Mitochondrial dysfunction and reduced prostaglandin synthesis in skeletal muscle of Group VIB (show SEMA6B ELISA Kits) Ca2 (show CA2 ELISA Kits)+-independent phospholipase A2gamma-deficient mice
iPLA(2)beta (show PLA2G6 ELISA Kits) and iPLA(2 (show PLA2G6 ELISA Kits))gamma are required for the adipogenic program that drives resting 3T3-L1 cells into adipocytes after hormone stimulation
iPLA2 (show PLA2G6 ELISA Kits) signaling plays an important role in glucose-stimulated insulin (show INS ELISA Kits) secretion under physiological conditions
iPLA(2 (show PLA2G6 ELISA Kits))gamma is essential for maintaining efficient bioenergetic mitochondrial function through tailoring mitochondrial membrane lipid metabolism and composition
the obligatory role of iPLA(2 (show PLA2G6 ELISA Kits))gamma in neuronal mitochondrial lipid metabolism and membrane structure demonstrating that iPLA(2 (show PLA2G6 ELISA Kits))gamma loss of function results in a mitochondrial neurodegenerative disorder
This gene encodes a member of the patatin-like phospholipase domain containing protein family. Members of this family are phospholipases which catalyze the cleavage of fatty acids from membrane phospholipids. The product of this gene is a calcium-independent phospholipase. A pseudogene of this gene is located on the X chromosome. Multiple transcript variants encoding different isoforms have been found for this gene.
, calcium-independent phospholipase A2-gamma
, iPLA2 gamma
, intracellular membrane-associated calcium-independent phospholipase A2 gamma
, membrane-associated calcium-independent phospholipase A2 gamma
, patatin-like phospholipase domain-containing protein 8
, group VIB calcium-independent phospholipase A2