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PNPLA8 encodes a member of the patatin-like phospholipase domain containing protein family. Additionally we are shipping Patatin-Like phospholipase Domain Containing 8 Proteins (3) and many more products for this protein.
Showing 10 out of 38 products:
Human Polyclonal PNPLA8 Primary Antibody for ICC, IF - ABIN4346574
Pattabiraman, Lih, Tomer, Rao: The role of calcium-independent phospholipase A2γ in modulation of aqueous humor drainage and Ca2+ sensitization of trabecular meshwork contraction. in American journal of physiology. Cell physiology 2012
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Cow (Bovine) Polyclonal PNPLA8 Primary Antibody for WB - ABIN2786886
Mungall, Palmer, Sims, Edwards, Ashurst, Wilming, Jones, Horton, Hunt, Scott, Gilbert, Clamp, Bethel, Milne, Ainscough, Almeida, Ambrose, Andrews, Ashwell, Babbage, Bagguley, Bailey, Banerjee, Barker et al.: The DNA sequence and analysis of human chromosome 6. ... in Nature 2003
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iPLA2gamma plays an important role in in vivo Thromboxane A2 production accompanied by thrombus formation.
iPLA2gamma plays a cardioprotective role during the acute stage of Chagas' disease.
Thus, complement-mediated activation of iPLA(2)gamma is mediated via ERK (show EPHB2 Antibodies) and p38 (show CRK Antibodies) pathways, and phosphorylation of Ser (show SIGLEC1 Antibodies)-511 and/or Ser (show SIGLEC1 Antibodies)-515 plays a key role in the catalytic activity and signaling of iPLA(2)gamma.
These results suggest distinct roles for iPLA2beta (show PLA2G6 Antibodies) and iPLA2gamma in cellular homeostasis and signaling, a functional link between peroxisomal AA release and eicosanoid generation, and a potential contribution of iPLA2gamma to tumorigenesis.
iPLA2 (show PLA2G6 Antibodies) activation is not sufficient for SOCE activation. iPLA2 (show PLA2G6 Antibodies) may regulate basal phosphoinositide metabolism
these results demonstrate the integrated roles of Cardiolipin and iPLA2gamma in lipid second-messenger production and mitochondrial bioenergetics during oxidative stress.
Because mitochondrial membrane depolarization and calcium are known to activate iPLA2gamma, these results are consistent with salvage of myocardium after Ischemia/Reperfusion by iPLA2gamma loss of function through decreasing mPTP (show PTPN2 Antibodies) opening, diminishing production of proinflammatory oxidized fatty acids
UCP2 (show UCP2 Antibodies), functional due to fatty acids released by redox-activated mt-iPLA2gamma, suppresses mitochondrial superoxide production by its uncoupling action.
Mitochondrial dysfunction and reduced prostaglandin synthesis in skeletal muscle of Group VIB (show SEMA6B Antibodies) Ca2 (show CA2 Antibodies)+-independent phospholipase A2gamma-deficient mice
iPLA(2)beta (show PLA2G6 Antibodies) and iPLA(2 (show PLA2G6 Antibodies))gamma are required for the adipogenic program that drives resting 3T3-L1 cells into adipocytes after hormone stimulation
iPLA2 (show PLA2G6 Antibodies) signaling plays an important role in glucose-stimulated insulin (show INS Antibodies) secretion under physiological conditions
iPLA(2 (show PLA2G6 Antibodies))gamma is essential for maintaining efficient bioenergetic mitochondrial function through tailoring mitochondrial membrane lipid metabolism and composition
the obligatory role of iPLA(2 (show PLA2G6 Antibodies))gamma in neuronal mitochondrial lipid metabolism and membrane structure demonstrating that iPLA(2 (show PLA2G6 Antibodies))gamma loss of function results in a mitochondrial neurodegenerative disorder
This gene encodes a member of the patatin-like phospholipase domain containing protein family. Members of this family are phospholipases which catalyze the cleavage of fatty acids from membrane phospholipids. The product of this gene is a calcium-independent phospholipase. A pseudogene of this gene is located on the X chromosome. Multiple transcript variants encoding different isoforms have been found for this gene.
, calcium-independent phospholipase A2-gamma
, iPLA2 gamma
, intracellular membrane-associated calcium-independent phospholipase A2 gamma
, membrane-associated calcium-independent phospholipase A2 gamma
, patatin-like phospholipase domain-containing protein 8
, group VIB calcium-independent phospholipase A2