anti-Patatin-Like phospholipase Domain Containing 3 (PNPLA3) Antibodies

The protein encoded by PNPLA3 is a triacylglycerol lipase that mediates triacylglycerol hydrolysis in adipocytes. Additionally we are shipping PNPLA3 Kits (14) and PNPLA3 Proteins (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PNPLA3 80339 Q9NST1
PNPLA3 116939 Q91WW7
PNPLA3 362972  
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Top anti-PNPLA3 Antibodies at antibodies-online.com

Showing 10 out of 93 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC, WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis in K562 cell line lysates (35ug/lane) using PNPLA3 Antibody (N-term) Cat.-No AP53370PU-N. This demonstrates the PNPLA3 antibody detected the PNPLA3 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$401.50
Details
Human Goat Un-conjugated IHC, ELISA, WB Antibody (0.05µg/ml) staining of Mouse Heart lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Antibody (0.01µg/ml) staining of Mouse (A) and Rat (B) Adrenal gland lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 6 to 7 Days
$326.89
Details
Human Goat Un-conjugated ELISA, IHC, IHC (p), WB Western Blot: Adiponutrin/PNPLA3 Antibody [NBP1-00227] - Staining of Mouse (A) and Rat (B) Adrenal gland lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Western Blot: Adiponutrin/PNPLA3 Antibody [NBP1-00227] - Staining of Mouse Heart lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 7 to 9 Days
$447.56
Details
Human Rabbit Un-conjugated WB PNPLA3 Antibody (N-term)  western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the PNPLA3 antibody detected the PNPLA3 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Dog Goat Un-conjugated EIA, IHC (p), WB   0.1 mg Log in to see 12 to 15 Days
$375.38
Details
Bat Goat Un-conjugated IHC (p), ELISA, WB 50 μg Log in to see 7 to 9 Days
$451.00
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$481.25
Details
Human Rabbit Un-conjugated IHC (p), WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Mouse Rabbit Un-conjugated WB Mouse Pnpla3 Antibody (C-term)  western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the Pnpla3 antibody detected the Pnpla3 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details

PNPLA3 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-PNPLA3 Antibodies

  1. Human Polyclonal PNPLA3 Primary Antibody for EIA, WB - ABIN954228 : Santoro, Kursawe, DAdamo, Dykas, Zhang, Bale, Calí, Narayan, Shaw, Pierpont, Savoye, Lartaud, Eldrich, Cushman, Zhao, Shulman, Caprio: A common variant in the patatin-like phospholipase 3 gene (PNPLA3) is associated with fatty liver disease in obese children and adolescents. in Hepatology (Baltimore, Md.) 2010 (PubMed)
    Show all 3 references for 954228

  2. Human Polyclonal PNPLA3 Primary Antibody for IHC, ELISA - ABIN361184 : Kumari, Schoiswohl, Chitraju, Paar, Cornaciu, Rangrez, Wongsiriroj, Nagy, Ivanova, Scott, Knittelfelder, Rechberger, Birner-Gruenberger, Eder, Brown, Haemmerle, Oberer, Lass, Kershaw, Zimmermann et al.: Adiponutrin functions as a nutritionally regulated lysophosphatidic acid acyltransferase. ... in Cell metabolism 2012 (PubMed)
    Show all 2 references for 361184

  3. Human Polyclonal PNPLA3 Primary Antibody for IHC, WB - ABIN2783569 : Wilson, Gardner, Lambie, Commans, Crowther: Characterization of the human patatin-like phospholipase family. in Journal of lipid research 2006 (PubMed)

  4. Human Polyclonal PNPLA3 Primary Antibody for ELISA, IHC - ABIN4278479 : Steinberg, Kemp, Watt: Adipocyte triglyceride lipase expression in human obesity. in American journal of physiology. Endocrinology and metabolism 2007 (PubMed)

More Antibodies against PNPLA3 Interaction Partners

Human Patatin-Like phospholipase Domain Containing 3 (PNPLA3) interaction partners

  1. The PNPLA3 rs738409 GG genotype is positively associated with hepatic steatosis in Asian patients with chronic hepatitis C.

  2. The study proposes that polymorphisms in the PNPLA3 gene have highly predictive value in the development of nonalcoholic fatty liver disease and are independently associated with the severity of liver histology in patients with NAFLD (show TSC2 Antibodies).

  3. PNPLA3 association with adiposity and the risk of the nonalcoholic fatty liver disease

  4. PNPLA3 gene variant is associated with the risk of developing liver fibrosis and cirrhosis in an Eastern European population.

  5. PNPLA3 acts as a positive modulator of activated human hepatic stellate cells, affecting cytokines secretion.

  6. The results show that in obese patients, the presence of the PNPLA3 p.I148M allele might be associated with greater improvement of hepatic steatosis after bariatric surgery in comparison to carriers of PNPLA3 wild-type alleles. The also lost more weight and had reduced liver fat content.

  7. Fibrosis stages were affected by the PNPLA3 (P = 0.042) and MBOAT7 (show MBOAT7 Antibodies) (P = 0.021) but not by the TM6SF2 polymorphism (P > 0.05). The PNPLA3, TM6SF2, and MBOAT7 (show MBOAT7 Antibodies) variants are associated with increased liver injury. The TM6SF2 variant seems to modulate predominantly hepatic fat accumulation, whereas the MBOAT7 (show MBOAT7 Antibodies) polymorphism is linked to fibrosis. The PNPLA3 polymorphism confers risk of both increased steatosis and fibrosis

  8. PNPLA3 rs738409 (C>G) was associated with the risk of both advanced liver fibrosis and steatosis in patients with chronic hepatitis C, especially among Caucasian populations

  9. we provide evidence to indicate that PNPLA3-mediated retinol release may protect against liver fibrosis by inducing a specific signature of proteins involved in extracellular matrix remodelling

  10. The percentage of the PNPLA3 rs738409 GG genotype in NAFLD (show TSC2 Antibodies) patients was also significantly higher than that in the controls.

Mouse (Murine) Patatin-Like phospholipase Domain Containing 3 (PNPLA3) interaction partners

  1. Neither ablation nor overexpression of wild-type PNPLA3 affects liver fat content in mice, whereas hepatic overexpression of the human 148M transgene causes steatosis.

  2. PNPLA3 plays a role in remodeling TAG in lipid droplets, as they accumulate in response to food intake

  3. adiponutrin/PNPLA3 is regulated by two key factors of the glycolytic and lipogenic pathways, raising the question of its implication in the metabolism of carbohydrates and lipids

  4. data argue against a role for Pnpla3 loss-of-function in fatty liver disease or metabolic syndrome in mice.

  5. Loss of Pnpla3 does not cause fatty liver, liver enzyme elevation, or insulin (show INS Antibodies) resistance in mice.

  6. Microarray-based gene profiling showed that the expression level of PNPLA3 in hepatocytes is correlated with that of genes associated with the lipogenic pathway such as ME1 (show ME1 Antibodies), SPOT14 (show THRSP Antibodies), and SCD1 (show SCD Antibodies).

  7. data suggest that murine ATGL (show PNPLA2 Antibodies) but not adiponutrin contributes to net adipocyte lipolysis and that ATGL (show PNPLA2 Antibodies) and adiponutrin are oppositely regulated by insulin (show INS Antibodies) both in vitro and in vivo

PNPLA3 Antigen Profile

Protein Summary

The protein encoded by this gene is a triacylglycerol lipase that mediates triacylglycerol hydrolysis in adipocytes. The encoded protein, which appears to be membrane bound, may be involved in the balance of energy usage/storage in adipocytes.

Gene names and symbols associated with PNPLA3

  • patatin-like phospholipase domain containing 3 (PNPLA3) antibody
  • patatin-like phospholipase domain containing 3 (Pnpla3) antibody
  • Adpn antibody
  • C22orf20 antibody
  • iPLA(2)epsilon antibody

Protein level used designations for PNPLA3

acylglycerol O-acyltransferase , adiponutrin , calcium-independent phospholipase A2-epsilon , iPLA2-epsilon , iPLA2epsilon , patatin-like phospholipase domain-containing protein 3

GENE ID SPECIES
80339 Homo sapiens
116939 Mus musculus
362972 Rattus norvegicus
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