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Paternally Expressed 3 (PEG3) ELISA Kits

In human, ZIM2 and PEG3 are treated as two distinct genes though they share multiple 5' exons and a common promoter and both genes are paternally expressed (PMID:15203203). Additionally we are shipping PEG3 Antibodies (30) and and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human PEG3 PEG3 5178 Q9GZU2
Anti-Mouse PEG3 PEG3 18616 Q3URU2
Anti-Rat PEG3 PEG3 246361  
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More ELISA Kits for PEG3 Interaction Partners

Pig (Porcine) Paternally Expressed 3 (PEG3) interaction partners

  1. Porcine skeletal muscle-derived PW1(pos)/Pax7(neg) interstitial cells are a source of stem/progenitor cells.

  2. The PEG3 gene expression was not affected by day of pregnancy or breed.

  3. For PEG3, pigs expressed the paternal allele in skeletal muscle, liver, spleen, kidney, and uterus, but biallele in heart, lung, fat, stomach, small intestine, and ovary.

Human Paternally Expressed 3 (PEG3) interaction partners

  1. In the current study, the authors have identified three alternative promoters for mouse Peg3 and one alternative promoter for human PEG3.

  2. A resident population of resident smooth muscle progenitor cells expressing PW1 was identified in pulmonary hypertension-associated vascular remodeling.

  3. PW1/Peg3 function is essential for conferring proper mesoangioblast competence and it's level in human mesoangioblasts may serve as a biomarker to identify donor populations for therapeutic application in muscular dystrophies.

  4. The PEG3-SCAN domain appears to constitute an assembly block, enabling PEG3 homo- or heterodimerization to control gene expression in a combinatorial fashion.

  5. Genetic translocations involving PEG3 gene is associated with mesenchymal hamartoma of the liver.

  6. we have unveiled a mechanism for a secreted proteoglycan (show Vcan ELISA Kits) in inducing Peg3, a master regulator of macroautophagy in endothelial cells

  7. Results show that a five percent increase in DNA methylation (show HELLS ELISA Kits) of PEG3 is associated with a 1.6-fold increase invasive cervical cancer (ICC) risk.

  8. None of the folate cycle genotypes in the mother or infant were related to the methylation of IGF2, PEG3, or LINE-1.

  9. PEG3 gene is imprinted, with preferential expression from the paternal allele in human placenta.

  10. mammalian imprinting utilizes Peg3/Pw1 to co-opt (show OPTC ELISA Kits) the Wnt (show WNT2 ELISA Kits) pathway, thereby regulating development and glioma growth

Cow (Bovine) Paternally Expressed 3 (PEG3) interaction partners

  1. the expression of PEG3 domain genes within the maternal placenta is not significantly affected by the MIMT1Del mutation and alterations in PEG3 domain gene expression on the fetal side

  2. Data show that a 110 kb microdeletion in the maternally imprinted PEG3 domain that results in a loss of paternal MIMT1 expression and causes late term abortion and stillbirth.

  3. Peg3 was seriously demethylated or showed aberrant methylation patterns in four aborted clones.

  4. PEG3 imprinted domain of humans, cows, and mice contains differing numbers of differentially methylated regions (DMR (show WDR20 ELISA Kits)), but the PEG3-CpG island is the only DMR (show WDR20 ELISA Kits) that is conserved among these three species.

Mouse (Murine) Paternally Expressed 3 (PEG3) interaction partners

  1. Data show that bisperoxovanadium (BpV) treatment induces specific epigenetic modifications at the promoter regions of genes associated with stem cell fate, including Sca-1 (show Ly6a ELISA Kits) and Pw1.

  2. 5'-GTGGCAGT-3'is a DNA-binding motif of PEG3.

  3. the milk letdown process was impaired in nursing females with the Peg3 mutation in the mammary gland, but not in the hypothalamus suggesting that Peg3's roles in the milk letdown process are more critical in the mammary gland than in the hypothalamus.

  4. Study reports, for the first time, the bi-allelic expression of Peg3 in specific areas of mouse brain.

  5. these results demonstrated that paternally expressed Peg3 controls maternally expressed Zim1 as a trans factor.

  6. Oocytes vitrification could lead to the loss of DNA methylation (show HELLS ELISA Kits) of imprinted genes (H19 (show NCKAP1 ELISA Kits), Peg3, and Snrpn (show SNRPN ELISA Kits)) in mouse blastocysts, which is mainly caused by the reductions of DNMTs after vitrification of oocytes.

  7. The down-regulation of Igf2 and Peg3 imprinted genes in adipocytes may be involved in the paternal transmission of high-fat diet-induced obesity.

  8. Mutant model revealed potential roles of Peg3 in reproduction. Female heterozygotes produced a much smaller number of mature oocytes than the wild-type littermates, resulting in reduced litter sizes.

  9. we have unveiled a mechanism for a secreted proteoglycan (show Vcan ELISA Kits) in inducing Peg3, a master regulator of macroautophagy in endothelial cells

  10. these results confirm PEG3 as a DNA-binding protein (show HSF4 ELISA Kits) controlling specific target genes that are involved in distinct cellular functions.

PEG3 Antigen Profile

Antigen Summary

In human, ZIM2 and PEG3 are treated as two distinct genes though they share multiple 5' exons and a common promoter and both genes are paternally expressed (PMID:15203203). Alternative splicing events connect their shared 5' exons either with the remaining 4 exons unique to ZIM2, or with the remaining 2 exons unique to PEG3. In contrast, in other mammals ZIM2 does not undergo imprinting and, in mouse, cow, and likely other mammals as well, the ZIM2 and PEG3 genes do not share exons. Human PEG3 protein belongs to the Kruppel C2H2-type zinc finger protein family. PEG3 may play a role in cell proliferation and p53-mediated apoptosis. PEG3 has also shown tumor suppressor activity and tumorigenesis in glioma and ovarian cells. Alternative splicing of this PEG3 gene results in multiple transcript variants encoding distinct isoforms.

Gene names and symbols associated with PEG3

  • paternally expressed 3 (PEG3) antibody
  • paternally expressed 3 (Peg3) antibody
  • AL022617 antibody
  • ASF-1 antibody
  • End4 antibody
  • Gcap4 antibody
  • mKIAA0287 antibody
  • PEG3 antibody
  • Pw1 antibody
  • Zfp102 antibody
  • ZKSCAN22 antibody
  • ZNF904 antibody
  • ZSCAN24 antibody

Protein level used designations for PEG3

paternally expressed 3 , paternally-expressed gene 3 protein-like , Kruppel-type zinc finger protein , paternally-expressed gene 3 protein , zinc finger and SCAN domain-containing protein 24 , paternally expressed gene 3 , zinc-finger protein , granule cell antiserum positive 4

707825 Macaca mulatta
100233196 Sus scrofa
100448879 Pongo abelii
100505405 Ovis aries
100510800 Felis catus
5178 Homo sapiens
476371 Canis lupus familiaris
100522552 Sus scrofa
444864 Bos taurus
18616 Mus musculus
469030 Pan troglodytes
246361 Rattus norvegicus
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