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anti-Pellino Homolog 1 (Drosophila) (PELI1) Antibodies

E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Additionally we are shipping Pellino Homolog 1 (Drosophila) Kits (5) and Pellino Homolog 1 (Drosophila) Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PELI1 67245 Q8C669
PELI1 57162 Q96FA3
PELI1 305549  
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Top anti-Pellino Homolog 1 (Drosophila) Antibodies at antibodies-online.com

Showing 10 out of 63 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of Pellino 1 in human liver tissue lysate with Pellino 1 Antibody  at (A) 1 and (B) 2 μg/ml. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-PELI1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: HepG2 cell lysate Host: Rabbit  Target Name: PELI1  Sample Tissue: Human 721_B  Antibody Dilution: 1.0 µg/mL PELI1 is supported by BioGPS gene expression data to be expressed in 721_B 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$330.00
Details
Human Rabbit Un-conjugated IHC (p), WB Anti-PELI1 antibody IHC staining of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN959413 dilution 1:100. 50 μL Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated WB PELI1 Antibody (Center) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the PELI1 antibody detected the PELI1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 8 to 10 Days
$507.83
Details
Human Rabbit Un-conjugated IHC (p), WB Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Mouse Un-conjugated WB   100 μL Log in to see 8 to 10 Days
$493.17
Details
Human Mouse Un-conjugated IHC (p)   100 μL Log in to see 8 to 10 Days
$493.17
Details

PELI1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine)


Human , ,
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Rat (Rattus)


Top referenced anti-Pellino Homolog 1 (Drosophila) Antibodies

  1. Human Polyclonal PELI1 Primary Antibody for EIA, WB - ABIN1450038 : Moynagh: The Pellino family: IRAK E3 ligases with emerging roles in innate immune signalling. in Trends in immunology 2009 (PubMed)

More Antibodies against Pellino Homolog 1 (Drosophila) Interaction Partners

Mouse (Murine) Pellino Homolog 1 (Drosophila) (PELI1) interaction partners

  1. The nonredundant role of Pellino1 in immune receptor signaling is in part due (show IRAK1 Antibodies)to its different substrate specificity.

  2. Pellino1 interacts with the transcription factor Deformed Epidermal Autoregulatory Factor 1 (DEAF1 (show DEAF1 Antibodies)).

  3. Peli1 is a microglia-specific mediator of autoimmune neuroinflammation that works by regulating Traf3 (show TRAF3 Antibodies) degradation

  4. These results demonstrate that the ligands that signal via MyD88 (show MYD88 Antibodies) do not always employ the same protein kinase (show CDK7 Antibodies) to activate Pellino 1 and show that the activiation of NF-kappaB (show NFKB1 Antibodies) and mitogen-activated protein kinases.

  5. Peli1 as a critical factor in the maintenance of peripheral T cell tolerance and demonstrate a previously unknown mechanism of c-Rel (show NFkBP65 Antibodies) regulation.

  6. Pellino-1 protein may have a cellular function distinct from previously identified functions.

  7. IKKepsilon (show IKBKE Antibodies)/TBK1 (show TBK1 Antibodies) mediate the activation of Pellino 1's E3 ligase activity, as well as inducing the transcription of its gene and protein expression in response to TLR3 (show TLR3 Antibodies) and TLR4 (show TLR4 Antibodies) agonists.

  8. miR (show MLXIP Antibodies)-21 expression was upregulated during early stages of liver regeneration. Targeting of Peli1 by miR (show MLXIP Antibodies)-21 could potentially provide the basis for a negative feedback cycle regulating NF-kappaB (show NFKB1 Antibodies) signaling.

  9. Peli1 is a ubiquitin ligase (show RNF123 Antibodies) needed for the transmission of TRIF (show RNF138 Antibodies)-dependent TLR signals.

Human Pellino Homolog 1 (Drosophila) (PELI1) interaction partners

  1. The study results in the Chinese Han population showed that PELI1 is a member of a constellation of genetic factors that may contribute to the pathogenesis of systemic lupus erythematosus.

  2. Increased PELI1 expression and subsequent induction of BCL6 (show BCL6 Antibodies) promotes lymphomagenesis.

  3. Peptide PEL1 derived from the interleukin-1 receptor-associated kinase (IRAK)1 (show IRAK1 Antibodies)-binding motif reveals a distinct phosphothreonine peptide binding preference.

  4. GWAS study found two new SNPs associated with nickel dermatitis; SNPs are located in the NTN4 and PELI1 genes

  5. Pellino1 interacts with the transcription factor Deformed Epidermal Autoregulatory Factor 1 (DEAF1 (show DEAF1 Antibodies)).

  6. incomplete KD, IVIG nonresponsiveness, long febrile days, and the rs7604693 genetic variant in the PELI1 gene are major risk factors for the development of CALs (show CA8 Antibodies)

  7. role in interleukin-1-mediated signalling through interaction with interleukin-1 receptor-associated kinase 4 (show IRAK4 Antibodies)-IRAK (show IRAK1 Antibodies)-tumor necrosis factor (show TNF Antibodies) receptor-associated factor 6 complex

  8. Smad6 (show SMAD6 Antibodies) bound to Pellino-1 promoted TGF-beta (show TGFB1 Antibodies)-mediated anti-inflammatory effects.

  9. kinase-inactive IRAK (show IRAK1 Antibodies) proteins can associate with Pellino proteins, thus excluding the possibility that their inability to regulate Pellino degradation is due to lack of association with the Pellino proteins

Pellino Homolog 1 (Drosophila) (PELI1) Antigen Profile

Protein Summary

E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Involved in the TLR and IL-1 signaling pathways via interaction with the complex containing IRAK kinases and TRAF6. Mediates 'Lys-63'-linked polyubiquitination of IRAK1 allowing subsequent NF-kappa-B activation (By similarity).

Gene names and symbols associated with PELI1

  • pellino 1 (Peli1) antibody
  • pellino E3 ubiquitin protein ligase 1 (PELI1) antibody
  • pellino E3 ubiquitin protein ligase 1 (Peli1) antibody
  • pellino homolog 1 (Drosophila) (PELI1) antibody
  • 2810468L03Rik antibody
  • A930031K15Rik antibody
  • AA409794 antibody
  • AI586297 antibody
  • D11Ertd676e antibody

Protein level used designations for PELI1

E3 ubiquitin-protein ligase pellino homolog 1 , pellino-1 , protein pellino homolog 1 , pellino homolog 1 , pellino-related intracellular-signaling molecule , pellino 1 , pellino protein

GENE ID SPECIES
67245 Mus musculus
57162 Homo sapiens
305549 Rattus norvegicus
421279 Gallus gallus
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