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anti-Peptidase Inhibitor 3, Skin-Derived (PI3) Antibodies

PI3 encodes an elastase-specific inhibitor that functions as an antimicrobial peptide against Gram-positive and Gram-negative bacteria. Additionally we are shipping Peptidase Inhibitor 3, Skin-Derived Kits (35) and Peptidase Inhibitor 3, Skin-Derived Proteins (11) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PI3 5266 P19957
PI3 20702 Q00896
PI3 408230  
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Top anti-Peptidase Inhibitor 3, Skin-Derived Antibodies at antibodies-online.com

Showing 10 out of 58 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-PI3 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: 721_B cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-PI3 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: 721_B cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated EIA, IHC (p), WB   0.1 mg Log in to see 6 to 8 Days
$643.50
Details
Human Mouse Un-conjugated EIA, IHC (p), WB   0.1 mg Log in to see 6 to 8 Days
$643.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Goat Un-conjugated EIA, IHC (p), WB   1 mL Log in to see 10 to 12 Days
$519.75
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Biotin IHC, ELISA, WB 100 μg Log in to see 11 to 13 Days
$424.60
Details
Human Mouse Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Log in to see 9 to 11 Days
$284.90
Details

PI3 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Peptidase Inhibitor 3, Skin-Derived Antibodies

  1. Human Monoclonal PI3 Primary Antibody for EIA, IHC (p) - ABIN1107081 : Vandermeeren, Daneels, Bergers, van Vlijmen-Willems, Pol, Geysen, Schalkwijk: Development and application of monoclonal antibodies against SKALP/elafin and other trappin family members. in Archives of dermatological research 2001 (PubMed)
    Show all 6 references for ABIN1107081

  2. Human Monoclonal PI3 Primary Antibody for EIA, IHC (p) - ABIN1107080 : Alkemade, van Vlijmen-Willems, van Haelst, van de Kerkhof, Schalkwijk: Demonstration of skin-derived antileukoproteinase (SKALP) and its target enzyme human leukocyte elastase in squamous cell carcinoma. in The Journal of pathology 1994 (PubMed)
    Show all 6 references for ABIN1107080

  3. Human Polyclonal PI3 Primary Antibody for EIA, IHC (p) - ABIN1107082 : van Bergen, Andriessen, Spruijt, van de Kerkhof, Schalkwijk: Expression of SKALP/elafin during wound healing in human skin. in Archives of dermatological research 1997 (PubMed)
    Show all 4 references for ABIN1107082

  4. Human Polyclonal PI3 Primary Antibody for WB - ABIN2782186 : Wang, Beach, Su, Zhai, Christiani: A genome-wide expression analysis in blood identifies pre-elafin as a biomarker in ARDS. in American journal of respiratory cell and molecular biology 2008 (PubMed)

More Antibodies against Peptidase Inhibitor 3, Skin-Derived Interaction Partners

Human Peptidase Inhibitor 3, Skin-Derived (PI3) interaction partners

  1. The expression of elafin in fallopian tubes of ectopic pregnancies is reduced.

  2. The elevations in cervical elafin and SLPI (show SLPI Antibodies) expression in the women with preterm delivery might reflect the local response to the pathogen invasion into the cervix preceding preterm labor.

  3. PI3 expression was downregulated in 24% of DCIS and 83% of invasive breast tumors. PI3 was also downregulated in 33% of ovarian cystadenomas, 43% of borderline ovarian tumors, and 86% of invasive ovarian carcinomas.

  4. The imbalance between neutrophil elastase (show ELANE Antibodies) and its inhibitors, such as elafin, presents an important therapeutic target in breast cancer.

  5. Higher urinary elafin levels are associated with an increased risk of micro- and macroalbuminuria, acute kidney injury and chronic kidney disease, and death after hematopoietic stem cell transplantation.

  6. cutaneous elafin does not seem to discriminate acute graft-versus-host disease from drug hypersensitivity rash lesions, but there may be an association between cutaneous elafin expression and poor prognosis for patients with cutaneous GVHD

  7. Data indicate that elafin overexpression is associated with poor overall survival.

  8. Low expression of elafin gene correlated with significantly reduced time to relapse, and when combined with high expression of elastase gene was associated with decreased survival in breast cancer patients

  9. Elafin has important roles in normal homoeostasis and at sites of inflammation. These roles include antiprotease and antimicrobial activity.

  10. Tubal epithelium from women with hydrosalpinx has lower levels of elafin expression.

Mouse (Murine) Peptidase Inhibitor 3, Skin-Derived (PI3) interaction partners

  1. Trappin-2 may therefore play an important role in innate recognition and clearance of pathogens during the very earliest stages of pulmonary infection.

Peptidase Inhibitor 3, Skin-Derived (PI3) Antigen Profile

Protein Summary

This gene encodes an elastase-specific inhibitor that functions as an antimicrobial peptide against Gram-positive and Gram-negative bacteria. The protein contains a WAP-type four-disulfide core (WFDC) domain, and is thus a member of the WFDC domain family. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the centromeric cluster. Expression of this gene is upgulated by bacterial lipopolysaccharides and cytokines.

Gene names and symbols associated with PI3

  • peptidase inhibitor 3, skin-derived (PI3) antibody
  • elafin (TOM) antibody
  • elafin (WAP-1) antibody
  • peptidase inhibitor 3, skin-derived (SKALP) (PI3) antibody
  • serine (or cysteine) peptidase inhibitor, clade A, member 1C (Serpina1c) antibody
  • WAP four-disulfide core domain 15B (Wfdc15b) antibody
  • cementoin antibody
  • elafin antibody
  • ESI antibody
  • Pi3 antibody
  • Pi6 antibody
  • Serpina1c antibody
  • Skalp antibody
  • Spi1-3 antibody
  • Spi1-6 antibody
  • trappin-2 antibody
  • Wap3 antibody
  • Wfdc14 antibody

Protein level used designations for PI3

elafin , elafin preproprotein , peptidase inhibitor 3, skin-derived (SKALP) , TRAPPIN-2 protein , trappin ovine homolog , elastase-specific inhibitor , skin-derived antileukoproteinase , peptidase inhibitor 3, skin-derived , protein WAP-1 , PI-3 , WAP four-disulfide core domain 14 , WAP four-disulfide core domain protein 14 , pre-elafin , protease inhibitor 3, skin-derived (SKALP) , protease inhibitor WAP3 , trappin-2 , alpha-1 protease inhibitor 3 , alpha-1 protease inhibitor 6 , alpha-1-antitrypsin 1-3 , alpha-1-antitrypsin 1-6 , apha-1 protease inhibitor 3 , serine (or cysteine) proteinase inhibitor, clade A, member 1c , serine protease inhibitor 1-3 , serine protease inhibitor 1-6 , serine protease inhibitor A1c , serpin A1c , WAP four-disulfide core domain protein 15B , WAP-type four-disulfide core 14 , protease inhibitor 3, skin-derived

GENE ID SPECIES
458276 Pan troglodytes
574237 Macaca mulatta
641305 Ovis aries
100137037 Pongo abelii
100137495 Papio anubis
100135056 Sus scrofa
5266 Homo sapiens
477241 Canis lupus familiaris
783871 Bos taurus
20702 Mus musculus
408230 Rattus norvegicus
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