You are viewing an incomplete version of our website. Please click to reload the website as full version.

Peptidyl Arginine Deiminase, Type II (PADI2) ELISA Kits

PADI2 encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. Additionally we are shipping Peptidyl Arginine Deiminase, Type II Antibodies (59) and Peptidyl Arginine Deiminase, Type II Proteins (10) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
PADI2 11240 Q9Y2J8
PADI2 18600 Q08642
PADI2 29511 P20717
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top Peptidyl Arginine Deiminase, Type II ELISA Kits at antibodies-online.com

Showing 3 out of 10 products:

Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Human 4.68 pg/ml 18.75-1200 pg/mL 96 Tests Log in to see 11 to 13 Days
$910.56
Details
Mouse 11.75 pg/ml 47-3000 pg/mL 96 Tests Log in to see 11 to 13 Days
$910.56
Details
Rat
96 Tests Log in to see 11 to 13 Days
$946.00
Details

More ELISA Kits for Peptidyl Arginine Deiminase, Type II Interaction Partners

Human Peptidyl Arginine Deiminase, Type II (PADI2) interaction partners

  1. We identified the presence of PADI3 (show PADI3 ELISA Kits) mRNA expression in synovial tissue and PADI2 and PADI4 (show PADI4 ELISA Kits) mRNA expressions in fibroblast-like synoviocytes from patients with rheumatoid arthritis.

  2. Protein arginine deiminase 2 binds six calcium ions in an ordered fashion.

  3. PAD2 activity was significantly higher in cell-free synovial fluid of rheumatoid arthritis patients compared to osteoarthritis patients.

  4. PAD2 activity was detected in synovial fluid samples from patients with rheumatoid arthritis.

  5. Report increased levels of extracellular PAD2 in the lungs of smokers.

  6. PADI2 and vimentin (show VIM ELISA Kits) participate in the apoptotic mechanisms of activated T lymphocytes.

  7. these studies provide the first genetic evidence that PAD2 functions as an oncogene and suggest that PAD2 may promote tumor progression by enhancing inflammation within the tumor microenvironment.

  8. PAD2 appears to use a substrate-assisted mechanism of catalysis in which the positively charged substrate guanidinium depresses the pKa of the nucleophilic cysteine

  9. Data suggest peptidylarginine deiminase 2 (PAD2) as a possible biomarker in various inflammatory diseases.

  10. PAD2 and PAD4 (show PADI4 ELISA Kits) have distinct substrate specificities.

Cow (Bovine) Peptidyl Arginine Deiminase, Type II (PADI2) interaction partners

Mouse (Murine) Peptidyl Arginine Deiminase, Type II (PADI2) interaction partners

  1. GPx7 (show GPX7 ELISA Kits) is an unusual CysGPx catalyzing the peroxidatic cycle by a one Cys (show DNAJC5 ELISA Kits) mechanism in which GSH and PDI (show PDIA3 ELISA Kits) are alternative substrates.

  2. Results suggest that PADI2 may function as an important new biomarker for HER2/ERBB2 (show ERBB2 ELISA Kits)+ tumors and that Cl-amidine represents a new candidate for breast cancer therapy.

  3. Activation of the P2X7 purinergic receptor (P2X7 (show P2RX7 ELISA Kits)) by the inflammatory danger signal ATP induces PAD2 activity and robust protein citrullination in mast cells.

  4. different subcellular compartmentalization of PADi2 and citrullinated proteins may have different physiological roles in normal and neurodegenerative conditions

  5. PAD2 interacts with IKKgamma (show IKBKG ELISA Kits) and suppresses NF-kappaB (show NFKB1 ELISA Kits) activity.

  6. Results suggest that peptidylarginine deiminase 2-catalyzed citrullination is not essential to the development of experimental autoimmune encephalomyelitis.

  7. An increase in citrullinated proteins resulting from increased PAD2 and 4 is an important change in the pathogenesis of multiple sclerosis.

  8. This study suggests that accumulated citrullinated proteins and abnormal activation of PAD2 may function in the pathogenesis of prion (show PRNP ELISA Kits) diseases and serve as potential therapeutic targets.

  9. elevated levels of the pro-inflammatory cytokine TNF-alpha and nuclear histone deimination support initiation of demyelination by increased PAD activity

Peptidyl Arginine Deiminase, Type II (PADI2) Antigen Profile

Antigen Summary

This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type II enzyme is the most widely expressed family member. Known substrates for this enzyme include myelin basic protein in the central nervous system and vimentin in skeletal muscle and macrophages. This enzyme is thought to play a role in the onset and progression of neurodegenerative human disorders, including Alzheimer disease and multiple sclerosis, and it has also been implicated in glaucoma pathogenesis. This gene exists in a cluster with four other paralogous genes.

Gene names and symbols associated with PADI2

  • peptidyl arginine deiminase, type II (PADI2) antibody
  • peptidyl arginine deiminase, type II (padi2) antibody
  • peptidyl arginine deiminase, type II (LOC100357368) antibody
  • peptidyl arginine deiminase, type II (Padi2) antibody
  • mKIAA0994 antibody
  • PAD-H19 antibody
  • PAD2 antibody
  • PADI2 antibody
  • Pdi antibody
  • Pdi2 antibody

Protein level used designations for PADI2

peptidyl arginine deiminase, type II , protein-arginine deiminase type-2-like , peptidlyarginine deiminase type II , peptidylarginine deiminase II , protein arginine deiminase , protein-arginine deiminase type II , protein-arginine deiminase type-2 , peptidyl arginine deiminase, type 2 , PAD type II , peptidyl arginine deiminase, type II; PAD type II

GENE ID SPECIES
456527 Pan troglodytes
711044 Macaca mulatta
100050025 Equus caballus
100125112 Xenopus (Silurana) tropicalis
100357368 Oryctolagus cuniculus
100437331 Pongo abelii
100473552 Ailuropoda melanoleuca
11240 Homo sapiens
380061 Xenopus laevis
428172 Gallus gallus
617851 Bos taurus
18600 Mus musculus
29511 Rattus norvegicus
487414 Canis lupus familiaris
100621356 Sus scrofa
Selected quality suppliers for Peptidyl Arginine Deiminase, Type II (PADI2) ELISA Kits
Did you look for something else?