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Peptidyl Arginine Deiminase, Type IV Proteins (PADI4)

PADI4 is a member of a gene family which encodes enzymes responsible for the conversion of arginine residues to citrulline residues. Additionally we are shipping PADI4 Antibodies (101) and PADI4 Kits (11) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PADI4 23569 Q9UM07
PADI4 18602 Q9Z183
PADI4 29512 O88807
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Top PADI4 Proteins at antibodies-online.com

Showing 10 out of 12 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Baculovirus infected Insect Cells Human His tag,GST tag,GST tag 10 μg Log in to see 16 Days
$301.88
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,934.33
Details
HOST_Escherichia coli (E. coli) Human His tag   50 μg Log in to see 5 Days
$522.50
Details
HOST_Baculovirus infected Insect Cells Human GST tag   50 μg Log in to see 10 to 12 Days
$570.24
Details
Insect Cells Mouse GST tag   100 μg Log in to see 24 to 29 Days
$594.83
Details
Insect Cells Human GST tag   100 μg Log in to see 24 to 29 Days
$410.03
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

PADI4 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , ,
, ,
Mouse (Murine) ,
,
Rat (Rattus)

Top referenced PADI4 Proteins

  1. Human PADI4 Protein expressed in Baculovirus infected Insect Cells - ABIN2003903 : Nakashima, Hagiwara, Ishigami, Nagata, Asaga, Kuramoto, Senshu, Yamada: Molecular characterization of peptidylarginine deiminase in HL-60 cells induced by retinoic acid and 1alpha,25-dihydroxyvitamin D(3). in The Journal of biological chemistry 1999 (PubMed)
    Show all 3 references for ABIN2003903

More Proteins for Peptidyl Arginine Deiminase, Type IV (PADI4) Interaction Partners

Human Peptidyl Arginine Deiminase, Type IV (PADI4) interaction partners

  1. We identified the presence of PADI3 (show PADI3 Proteins) mRNA expression in synovial tissue and PADI2 (show PADI2 Proteins) and PADI4 mRNA expressions in fibroblast-like synoviocytes from patients with rheumatoid arthritis.

  2. Polymorphism in exon-4 of PADI4 gene showed significant association with rheumatoid arthritis (RA)and polymorphism in exon-3 exhibited moderate association with RA.

  3. PADI4 rs1748033 gene polymorphism increased the risk of RA in a sample of the Iranian population.

  4. Silencing of PADI4 attenuates the TNF-alpha (show TNF Proteins)-induced osteogenic differentiation of human mesenchymal stem cells.

  5. Data show that peptidylarginine deiminase type 4, mutated citrullinated vimentin (show VIM Proteins) and cyclic citrullinated peptides autoantibodies were detected in 24, 61 and 74% of rheumatoid arthritis (RA) patients, respectively.

  6. PAD4 activity was significantly higher in cell-free synovial fluid of rheumatoid arthritis patients compared to osteoarthritis patients.

  7. Data show that peptidyl arginine deiminase type IV (PADI4) polymorphisms and a functional haplotype are associated with rheumatoid arthritis.

  8. PAD-4 is inhibited by PTPN22 (show PTPN22 Proteins).

  9. PADI4-94G/A polymorphism is associated with susceptibility to rheumatoid arthritis in the overall population and in the Asian population.

  10. We propose that the influence of PADI4 on IL6ST (show IL6ST Proteins) transcription plays a role in the control of IL6ST (show IL6ST Proteins) expression during lineage differentiation of hematopoietic stem/progenitor cells.

Mouse (Murine) Peptidyl Arginine Deiminase, Type IV (PADI4) interaction partners

  1. PADI4 exacerbates arthritis with diverse immunological modifications.

  2. Selective inhibition of peptidylarginine deiminase IV with Cl-amidine blocked NET formation, reduced atherosclerotic lesion area, and delayed time to carotid artery thrombosis in a photochemical injury model.

  3. Padi4 is part of the pluripotency transcriptional network, binding to regulatory elements of key stem-cell genes and activating their expression

  4. PAD4 regulates the proliferation of multipotent progenitors in the bone marrow by controlling c-myc (show MYC Proteins) expression.

  5. PAD4-mediated chromatin decondensation in the neutrophil is crucial for pathological venous thrombosis and present neutrophil activation and PAD4 as potential drug targets for deep vein thrombosis.

  6. PAD4 is dispensable in this effector phase model of arthritis

  7. analysis of regulation of histone modification and chromatin structure by the p53 (show TP53 Proteins)-PADI4 pathway

  8. An increase in citrullinated proteins resulting from increased PAD2 and 4 is an important change in the pathogenesis of multiple sclerosis.

PADI4 Protein Profile

Protein Summary

This gene is a member of a gene family which encodes enzymes responsible for the conversion of arginine residues to citrulline residues. This gene may play a role in granulocyte and macrophage development leading to inflammation and immune response.

Gene names and symbols associated with PADI4

  • peptidyl arginine deiminase, type IV (PADI4)
  • peptidyl arginine deiminase, type IV (Padi4)
  • PAD protein
  • Pad4 protein
  • PADI5 protein
  • Pdi4 protein
  • PDI5 protein

Protein level used designations for PADI4

peptidyl arginine deiminase, type IV , protein-arginine deiminase type-4-like , HL-60 PAD , PADI-H protein , peptidyl arginine deiminase, type V , protein-arginine deiminase type IV , protein-arginine deiminase type-4 , PAD type IV , peptidylarginine deiminase IV , PAD-R4 , peptidyl arginine deiminase, type 4 , peptidylarginine deiminase type alpha

GENE ID SPECIES
100026011 Monodelphis domestica
100049826 Equus caballus
100415489 Callithrix jacchus
100471129 Ailuropoda melanoleuca
100592291 Nomascus leucogenys
23569 Homo sapiens
18602 Mus musculus
456530 Pan troglodytes
29512 Rattus norvegicus
606921 Canis lupus familiaris
508161 Bos taurus
100524749 Sus scrofa
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