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anti-Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1) Antibodies

Peptidyl-prolyl cis/trans isomerases (PPIases) catalyze the cis/trans isomerization of peptidyl-prolyl peptide bonds. Additionally we are shipping Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 Proteins (21) and Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 Kits (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PIN1 241593  
PIN1 5300 Q13526
PIN1 298696  
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Top anti-Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 Antibodies at antibodies-online.com

Showing 10 out of 174 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC, ELISA, WB Western blot analysis of extracts from COS7 cells treated with insulin... Immunohistochemistry analysis of paraffin-embedded human heart, using ... 100 μg Log in to see 2 to 3 Days
$275.00
Details
Human Rabbit Un-conjugated FACS, IF, IHC (p), WB Western blot analysis of PIN1 Antibody (Center) (ABIN652906) in HL-60 ... Formalin-fixed and paraffin-embedded human lung carcinoma reacted with... 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IF, ELISA Immunofluorescence analysis of NIH-3T3 cells, using Pin1 (Ab-1619) Ant... 100 μg Log in to see 2 to 3 Days
$275.00
Details
Cow Rabbit Un-conjugated EIA, WB 0.1 mg Log in to see 6 to 8 Days
$500.50
Details
Rat Goat Un-conjugated ELISA, WB ABIN185726 (0.2µg/ml) staining of Rat Brain lysate (35µg protein in RI... 100 μg Log in to see 4 to 5 Days
$318.20
Details
Dog Goat Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Mouse Un-conjugated WB PIN1 Antibody (ABIN1882275) western blot analysis in Hela,293,mouse NI... 400 μL Log in to see 10 to 11 Days
$324.50
Details
Mouse Rabbit Un-conjugated EIA, WB   0.1 mg Log in to see 6 to 8 Days
$456.50
Details
Human Rabbit Un-conjugated EIA, WB   0.1 mg Log in to see 6 to 8 Days
$456.50
Details
Dog Mouse Un-conjugated EIA, WB 0.1 mg Log in to see 6 to 8 Days
$533.50
Details

PIN1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Mouse (Murine) , , , ,
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Human , , , ,
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Rat (Rattus) , , , ,
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Top referenced anti-Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 Antibodies

  1. Mouse (Murine) Polyclonal PIN1 Primary Antibody for EIA, WB - ABIN493366 : Campaner, Kaldis, Izraeli, Kirsch: Sil phosphorylation in a Pin1 binding domain affects the duration of the spindle checkpoint. in Molecular and cellular biology 2005 (PubMed)
    Show all 5 references for ABIN493366

  2. Human Polyclonal PIN1 Primary Antibody for EIA, WB - ABIN493364 : Lim, Balastik, Lee, Nakamura, Liou, Sun, Finn, Pastorino, Lee, Lu: Pin1 has opposite effects on wild-type and P301L tau stability and tauopathy. in The Journal of clinical investigation 2008 (PubMed)
    Show all 5 references for ABIN493364

  3. Cow (Bovine) Polyclonal PIN1 Primary Antibody for EIA, WB - ABIN401395 : Esnault, Shen, Whitesel, Malter: The peptidyl-prolyl isomerase Pin1 regulates granulocyte-macrophage colony-stimulating factor mRNA stability in T lymphocytes. in Journal of immunology (Baltimore, Md. : 1950) 2006 (PubMed)
    Show all 2 references for ABIN401395

  4. Human Polyclonal PIN1 Primary Antibody for IF, ELISA - ABIN1532476 : Lu, Hanes, Hunter: A human peptidyl-prolyl isomerase essential for regulation of mitosis. in Nature 1996 (PubMed)
    Show all 2 references for ABIN1532476

  5. Human Monoclonal PIN1 Primary Antibody for WB - ABIN1882275 : Ota, Suzuki, Nishikawa, Otsuki, Sugiyama, Irie, Wakamatsu, Hayashi, Sato, Nagai, Kimura, Makita, Sekine, Obayashi, Nishi, Shibahara, Tanaka, Ishii, Yamamoto, Saito, Kawai, Isono, Nakamura, Nagahari et al.: Complete sequencing and characterization of 21,243 full-length human cDNAs. ... in Nature genetics 2003 (PubMed)

  6. Rat (Rattus) Polyclonal PIN1 Primary Antibody for ELISA, WB - ABIN185726 : Pastorino, Sun, Lu, Zhou, Balastik, Finn, Wulf, Lim, Li, Li, Xia, Nicholson, Lu: The prolyl isomerase Pin1 regulates amyloid precursor protein processing and amyloid-beta production. in Nature 2006 (PubMed)

More Antibodies against Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 Interaction Partners

Mouse (Murine) Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1) interaction partners

  1. diet containing high phosphate induces rapid renal fibrosis before a significant impact on renal function and Pin1 plays an important role in the fibrotic process.

  2. Pin1 is indispensable for Wnt3a (show WNT3A Antibodies)-induced osteoblast differentiation.

  3. Pin1 regulates the osteogenic activity of Osterix (show SP7 Antibodies).

  4. Pin1-dependent signaling represents a mechanism to modulate GABAergic transmission by regulating NL2 (show MMEL1 Antibodies)/gephyrin (show GPHN Antibodies) interaction.

  5. PIN1 regulates pulmonary effects of endotoxin and tumor necrosis factor-alpha (show TNF Antibodies) in mice.

  6. Thus, Pin1 could be developed as a major therapeutic target in many skeletal diseases

  7. Results show that DLX5 (show DLX5 Antibodies), p63 (show CKAP4 Antibodies), Pin1 and FGF8 (show FGF8 Antibodies) participate to the same time- and location-restricted regulatory loop essential for apical ectodermal ridge stratification, hence for normal patterning and skeletal morphogenesis of the limb buds.

  8. Pin1 induction during liver fibrosis is involved in hepatic stellate cell activation, TGFbeta1 (show TGFB1 Antibodies) expression, and TGFbeta1 (show TGFB1 Antibodies)-mediated fibrogenesis signalling.

  9. The identification of Pin1 as a factor involved in cell fusion contributes to the understanding of osteoclast-associated diseases, including osteoporosis, and opens new avenues for therapeutic targets.

  10. Studied genome-wide mRNA expression microarray using the RNA isolation from Pin1 (+/+) and Pin1 (-/-) mouse embryonic fibroblast (MEF) cells. Signaling pathways regulated by Pin1 were analyzed with the utility of KEGG pathway and GO annotation.

Xenopus laevis Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1) interaction partners

  1. Pin1 is an essential factor regulating CPEB degradation

  2. Pin1 binding is required for the inactivation of XeWee1B at M phase, presumably causing isomerization of the phospho-TP motif and thereby impairing the function of the Wee (show WEE1 Antibodies)-box

Human Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1) interaction partners

  1. Structural Analysis of the Pin1-CPEB1 (show CPEB1 Antibodies) interaction and its potential role in CPEB1 (show CPEB1 Antibodies) degradation has been described.

  2. Data show that Prolyl isomerase Pin1 is expressed in an epidermal growth factor receptor (EGFR (show EGFR Antibodies))-mutant lung cancer tissue that has undergone partial epithelial-mesenchymal transition (EMT (show ITK Antibodies)) and acquired resistance to EGFR (show EGFR Antibodies) tyrosine kinase (show TXK Antibodies) inhibitors (TKIs).

  3. Report shows that PIN1 binds to and stabilizes HIF-1alpha (show HIF1A Antibodies), consequently enhancing the angiogenesis.

  4. This shows that Pin1 is implemented in maintaining the susceptibility to the genotoxic drugs by controlling P-gp (show ABCB4 Antibodies) level as well as p53 (show TP53 Antibodies)-dependent apoptosis and cell cycle signaling pathways.

  5. Activation of BAX (show BAX Antibodies) through the concerted action of cytosolic p53 (show TP53 Antibodies) and Pin1 may integrate cell stress signals to induce a direct apoptotic response.

  6. The roles of the three tryptophan residues (W11, W34 and W73)in maintaining the structure and the function of Pin1

  7. Expression of Pin1 was decreased at or above the Cd IC50 value and was inversely correlated with the level of phospho-Ser (show SIGLEC1 Antibodies)-GSK3alphabeta in oral squamous cell carcinoma.

  8. ZBP-89 (show ZNF148 Antibodies) attenuates HDAC3 (show HDAC3 Antibodies) by increasing IkappaB degradation, dependent on Pin1 but independent of NF-Kappab (show NFKB1 Antibodies)

  9. Peptidyl-Prolyl cis/trans Isomerase NIMA-Interacting 1 as a Therapeutic Target in Hepatocellular Carcinoma

  10. These findings suggest the potential effectiveness of Pin1 inhibitors as therapeutic agents for prostate cancers, regardless of their androgen sensitivity.

Cow (Bovine) Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1) interaction partners

  1. The data provide the first evidence that Pin 1 expression in the granulosa cells but not the theca cells changes during follicular development, and that FSH (show BRD2 Antibodies) stimulate the expression of the Pin 1 gene.

Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1) Antigen Profile

Protein Summary

Peptidyl-prolyl cis/trans isomerases (PPIases) catalyze the cis/trans isomerization of peptidyl-prolyl peptide bonds. This gene encodes one of the PPIases, which specifically binds to phosphorylated ser/thr-pro motifs to catalytically regulate the post-phosphorylation conformation of its substrates. The conformational regulation catalyzed by this PPIase has a profound impact on key proteins involved in the regulation of cell growth, genotoxic and other stress responses, the immune response, induction and maintenance of pluripotency, germ cell development, neuronal differentiation, and survival. This enzyme also plays a key role in the pathogenesis of Alzheimer's disease and many cancers. Multiple alternatively spliced transcript variants have been found for this gene.

Gene names and symbols associated with PIN1

  • protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1, retrogene 1 (Pin1rt1) antibody
  • peptidylprolyl cis/trans isomerase, NIMA-interacting 1 (pin1-b) antibody
  • peptidylprolyl cis/trans isomerase, NIMA-interacting 1 (pin1) antibody
  • peptidylprolyl cis/trans isomerase, NIMA-interacting 1 (pin1-a) antibody
  • peptidylprolyl cis/trans isomerase, NIMA-interacting 1 (PIN1) antibody
  • peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (ppiD) antibody
  • peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PITG_11123) antibody
  • peptidylprolyl cis/trans isomerase, NIMA-interacting 1 (Pin1) antibody
  • protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1 (Pin1) antibody
  • 0610025L01Rik antibody
  • D9Bwg1161e antibody
  • DOD antibody
  • OTTMUSG00000014964 antibody
  • pin1 antibody
  • Pin1-ps1 antibody
  • pin1a antibody
  • pin1b antibody
  • Pin1l antibody
  • UBL5 antibody

Protein level used designations for PIN1

peptidylprolyl cis/trans isomerase, NIMA-interacting 1 , peptidylprolyl cis/trans isomerase, NIMA-interacting 1, pseudogene 1 , prolyl isomerase Pin1 b , prolyl isomerase Pin1 , peptidylprolyl cis/trans isomerase, NIMA-interacting 1 b , protein (peptidylprolyl cis/trans isomerase) NIMA-interacting 1 , peptidylprolyl cis/trans isomerase, NIMA-interacting 1 a , peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 , PPIase Pin1 , protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1 , rotamase Pin1 , peptidyl-prolyl cis-trans isomerase Pin1

GENE ID SPECIES
241593 Mus musculus
399385 Xenopus laevis
493472 Xenopus (Silurana) tropicalis
503670 Xenopus laevis
711095 Macaca mulatta
745021 Pan troglodytes
5807350 Sorangium cellulosum So ce56
9476290 Phytophthora infestans T30-4
5300 Homo sapiens
484963 Canis lupus familiaris
298696 Rattus norvegicus
535470 Bos taurus
100512827 Sus scrofa
23988 Mus musculus
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