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anti-Peptidylprolyl Isomerase A (Cyclophilin A) (PPIA) Antibodies

PPIA encodes a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. Additionally we are shipping PPIA Proteins (52) and PPIA Kits (51) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PPIA 268373 P17742
PPIA 5478 P62937
PPIA 25518 P10111
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Top anti-PPIA Antibodies at antibodies-online.com

Showing 10 out of 155 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-PPIA Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Human brain 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Goat Un-conjugated EIA, WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of PPIA Antibody 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Dog Rabbit Un-conjugated IHC, WB WB Suggested Anti-PPIA Antibody Titration: 2.5ug/mlPositive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Goat Un-conjugated ELISA, WB ABIN185542 (2µg/ml) staining of human lymph node lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Rabbit Un-conjugated IF (p), IHC (p) Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti-CYPA Polyclonal Antibody, Unconjugated (ABIN759716) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of PPIA Antibody (N-term) (ABIN389487) in T47D cell line and mouse brain,bladder tissue lysates (35 µg/lane). PPIA (arrow) was detected using the purified polyclonal antibody.(2 µg/mL) Formalin-fixed and paraffin-embedded human brain tissue reacted with PPIA Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated ICC, IF, IHC (p), WB WB Image Cyclophilin A antibody detects Cyclophilin A protein by western blot analysis. Raji whole cell extracts and cytoplasma+membrane and nuclear extracts (30 μg) were separated by 12% SDS-PAGE, and the membrane was blotted with Cyclophilin A antibody , at a dilution of 1:5000. IHC-P Image Immunohistochemical analysis of paraffin-embedded MDA-MB-468 xenograft, using Cyclophilin A, antibody at 1:500 dilution. 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Rabbit Un-conjugated IHC (p), WB Anti-Cyclophilin A antibody, IHC(P) IHC(P): Human Placenta Tissue Anti-Cyclophilin A antibody, Western blotting Lane 1: CEM Cell Lysate Lane 2: RAJI Cell Lysate 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Mouse Un-conjugated ELISA, WB PPIA monoclonal antibody (M01), clone 1F4-1B5 Western Blot analysis of PPIA expression in Jurkat . Detection limit for recombinant GST tagged PPIA is approximately 0.03ng/ml as a capture antibody. 100 μg Log in to see 9 Days
$430.00
Details

PPIA Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-PPIA Antibodies

  1. Human Monoclonal PPIA Primary Antibody for ELISA, WB - ABIN562340 : Rho, Roehrl, Wang: Tissue proteomics reveals differential and compartment-specific expression of the homologs transgelin and transgelin-2 in lung adenocarcinoma and its stroma. in Journal of proteome research 2009 (PubMed)
    Show all 3 references for ABIN562340

  2. Human Polyclonal PPIA Primary Antibody for IF (p), IHC (p) - ABIN759716 : Kang, Kim, Hong, Park, Heinsen, Lee, Ravid, Ferrer, Yoo, Kwon, Park: Large-scale analysis of posttranslational modifications in the hippocampus of patients with Alzheimer's disease using pI shift and label-free quantification without enrichment. in Analytical and bioanalytical chemistry 2014 (PubMed)

  3. Human Polyclonal PPIA Primary Antibody for WB - ABIN2784531 : Yang, Robotham, Nelson, Irsigler, Kenworthy, Tang: Cyclophilin A is an essential cofactor for hepatitis C virus infection and the principal mediator of cyclosporine resistance in vitro. in Journal of virology 2008 (PubMed)

  4. Human Polyclonal PPIA Primary Antibody for ELISA, WB - ABIN185542 : Berthoux, Sebastian, Sokolskaja, Luban: Cyclophilin A is required for TRIM5{alpha}-mediated resistance to HIV-1 in Old World monkey cells. in Proceedings of the National Academy of Sciences of the United States of America 2005 (PubMed)

  5. Dog (Canine) Polyclonal PPIA Primary Antibody for IHC, WB - ABIN2784530 : Sokolskaja, Berthoux, Luban: Cyclophilin A and TRIM5alpha independently regulate human immunodeficiency virus type 1 infectivity in human cells. in Journal of virology 2006 (PubMed)

  6. Human Polyclonal PPIA Primary Antibody for EIA, WB - ABIN453288 : Braaten, Ansari, Luban: The hydrophobic pocket of cyclophilin is the binding site for the human immunodeficiency virus type 1 Gag polyprotein. in Journal of virology 1997 (PubMed)

More Antibodies against PPIA Interaction Partners

Xenopus laevis Peptidylprolyl Isomerase A (Cyclophilin A) (PPIA) interaction partners

Mouse (Murine) Peptidylprolyl Isomerase A (Cyclophilin A) (PPIA) interaction partners

  1. Extracellular CyPA activates platelets via cluster of differentiation 147-mediated phosphoinositid-3-kinase/Akt (show AKT1 Antibodies)-signaling, leading to enhanced adhesion and thrombus formation independently of intracellular CyPA.

  2. CypA provided stability for NF-kappaB (show NFKB1 Antibodies) p65 (show NFkBP65 Antibodies) and promoted NF-kappaB (show NFKB1 Antibodies) p65 (show NFkBP65 Antibodies) nuclear translocation, resulting in increased nuclear accumulation and enhanced NF-kappaB (show NFKB1 Antibodies) activity.

  3. Newborn CypA-deficient pups exhibited generalized, pronounced skeletal defects, while high-resolution micro-computed tomography analyses of the femurs and lumbar vertebrae revealed delayed or incomplete endochondral ossification.

  4. Cyclophilin A secretion was increased in lymphocytes from atherogenic mice.

  5. CD137 (show TNFRSF9 Antibodies)-CD137L (show TNFSF9 Antibodies) interactions mediated via regulation of CyPA contribute to the progression of atherosclerosis.

  6. Reactive oxygen species-dependent CypA secretion by endothelial cells is an important signaling mechanism through which endothelial cell reactive oxygen species regulate susceptibility of structural components of the aortic wall to aortic dissection.

  7. CyPA is an important regulator for AngII-induced ROS (show ROS1 Antibodies) generation in VSMC through interaction with p47phox (show NCF1 Antibodies) and cell cytoskeleton, which enhances the translocation of p47phox (show NCF1 Antibodies) to caveolae.

  8. CYPA was identified as a novel host restriction factor that confered protection against rotavirus infection.

  9. CyPA expression increases and may modulate inflammatory cell adhesion and interleukin-6 (show IL6 Antibodies) expression inducing vascular smooth muscle cell migration and inflammatory cell extravasation in a time-dependent manner

  10. How does oxidative stress contribute to vascular disease? Data from vascular smooth muscle suggest that reduced glutathione peroxidase 1 (show GPX1 Antibodies) (i.e., oxidative stress) promotes secretion of CypA which mediates paracrine inflammation of vasculature.

Human Peptidylprolyl Isomerase A (Cyclophilin A) (PPIA) interaction partners

  1. the states of phosphorylation of Cyp (show PPIG Antibodies) A by Akt (show AKT1 Antibodies) can influence the progress of the cell cycle in multiple myeloma.

  2. review of PPIA polymorphisms and what is known about their impact on the replication cycle and course of disease for different viral infections

  3. The present knowledge on the role of cyclophilin A during coronavirus replication is summarized (Review)

  4. CsA (show ERCC8 Antibodies) and FK506 might interfere with selected effector T cell functions via a CrkII (show CRK Antibodies)-, but not CrkI-dependent mechanisms.

  5. Extracellular CyPA activates platelets via cluster of differentiation 147-mediated phosphoinositid-3-kinase/Akt (show AKT1 Antibodies)-signaling, leading to enhanced adhesion and thrombus formation independently of intracellular CyPA.

  6. Overexpression of CypA/WT protected the cells against cisplatin or H2O2-induced oxidative damage, however, the CypA/P16S mutant had no effect. These findings suggested that CypA exhibits a protective antioxidant effect

  7. The poor prognosis of esophageal cancer patients was associated with high expression of CypA.

  8. These results indicate a special function mode for CypA of playing more important roles in the early stage of gastric tumorigenesis.

  9. Cyclophilin A regulates HIV-1 replication kinetics and infectivity, modulates sensitivity to host restriction factors, and cooperates in the transit of the pre-integration complex into the nucleus of infected cells.

  10. The frequency of immunihistochemistry detected cyclophilin A protein expression was found to be equal in tumor of both histotypes.

PPIA Antigen Profile

Protein Summary

This gene encodes a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. The encoded protein is a cyclosporin binding-protein and may play a role in cyclosporin A-mediated immunosuppression. The protein can also interact with several HIV proteins, including p55 gag, Vpr, and capsid protein, and has been shown to be necessary for the formation of infectious HIV virions. Multiple pseudogenes that map to different chromosomes have been reported.

Gene names and symbols associated with PPIA

  • peptidylprolyl isomerase A (cyclophilin A) (PPIA) antibody
  • peptidylprolyl isomerase Aa (cyclophilin A) (ppiaa) antibody
  • peptidylprolyl isomerase A (cyclophilin A) (ppia) antibody
  • cyclophilin A (CypA) antibody
  • cyclophilin A (Cypa) antibody
  • cyclophilin A (CNB01230) antibody
  • cyclophilin A (CNB01290) antibody
  • cyclophilin A (Tc00.1047053506925.300) antibody
  • cyclophilin A (Tb11.03.0250) antibody
  • cyclophilin a (LmjF25.0910) antibody
  • olfactory receptor, family 4, subfamily L, member 1-like (LOC788146) antibody
  • peptidyl-prolyl cis-trans isomerase A-like (LOC100773511) antibody
  • peptidylprolyl isomerase A (Ppia) antibody
  • peptidylprolyl isomerase A (cyclophilin A) (Ppia) antibody
  • 2700098C05 antibody
  • Cphn antibody
  • CYCA antibody
  • CyP-18 antibody
  • CyP-A antibody
  • Cyp1 antibody
  • cypA antibody
  • CYPH antibody
  • fa93g09 antibody
  • MGC75715 antibody
  • MT-ND1 antibody
  • MTND1 antibody
  • NADH1 antibody
  • ND1 antibody
  • PPIA antibody
  • PPIA-2 antibody
  • wu:fa93g09 antibody
  • wu:fb05e11 antibody
  • wu:fb13h02 antibody
  • wu:fb15a05 antibody

Protein level used designations for PPIA

peptidyl-prolyl cis-trans isomerase A , 2-peptidylprolyl isomerase A , peptidylprolyl isomerase A (cyclophilin A) , cyclophilin A , immunophilin , PPIase A , cyclosporin A-binding protein , rotamase A , cyclophilin-like , cyclophilin a , Cyclophilin A , Cyclosporin A-binding protein , Rotamase A , Peptidyl-prolyl cis-trans isomerase A , SP18 , T cell cyclophilin , cyclophilin , p1B15 , p31 , cyclophilin T , cyclophilin T-cell , cyclophilin 18 , NADH dehydrogenase subunit 1 , NADH-ubiquinone oxidoreductase chain 1

GENE ID SPECIES
100173012 Pongo abelii
336612 Danio rerio
394470 Xenopus (Silurana) tropicalis
398630 Xenopus laevis
403581 Canis lupus familiaris
463386 Pan troglodytes
606861 Canis lupus familiaris
692737 Bombyx mori
786614 Bos taurus
3255869 Cryptococcus neoformans var. neoformans JEC21
3255972 Cryptococcus neoformans var. neoformans JEC21
3554513 Trypanosoma cruzi strain CL Brener
3664945 Trypanosoma brucei brucei strain 927/4 GUTat10.1
5652501 Leishmania major strain Friedlin
100594480 Nomascus leucogenys
788146 Bos taurus
100773511 Cricetulus griseus
268373 Mus musculus
5478 Homo sapiens
608151 Canis lupus familiaris
25518 Rattus norvegicus
397637 Sus scrofa
281418 Bos taurus
100008724 Oryctolagus cuniculus
493966 Felis catus
776282 Gallus gallus
443258 Ovis aries
574102 Macaca mulatta
473924 Pan troglodytes
100973085 Pan paniscus
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