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anti-Periaxin (PRX) Antibodies

PRX encodes a protein involved in peripheral nerve myelin upkeep. Additionally we are shipping Periaxin Kits (4) and Periaxin Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PRX 57716 Q9BXM0
PRX 19153 O55103
PRX 78960 Q63425
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Top anti-Periaxin Antibodies at antibodies-online.com

Showing 10 out of 26 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat brain tissue labeled with Anti-PRX Polyclonal Antibody, Cy3 Conjugated  at 1:100 for 40 minutes at 37°C. DAPI dye is used to highlight the nuclei. 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Alexa Fluor 594 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Biotin IHC (p), WB   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit FITC IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 647 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 488 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 350 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 555 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Cy3 IF (p)   100 μL Log in to see 14 to 21 Days
$379.50
Details
Human Rabbit Cy5.5 IF (p)   100 μL Log in to see 14 to 21 Days
$379.50
Details

PRX Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Mouse (Murine) ,


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Rat (Rattus) ,


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More Antibodies against Periaxin Interaction Partners

Human Periaxin (PRX) interaction partners

  1. we were able to simplify this complex phenotype and identified a causative mutation (p.R1070*) in the gene periaxin (PRX), a gene previously shown to cause peripheral neuropathy (Dejerine-Sottas syndrome) when this mutation is present

  2. Study of the periaxin gene should be considered in patients with severe demyelinating neuropathy associated with early infantile scoliosis.

  3. a variation of clinical phenotypes for CMT4F caused by a novel, nonsense PRX (show PRDX6 Antibodies) mutation, was shown.

  4. Novel mutations in the PRX (show PRDX6 Antibodies) and the MTMR2 (show MTMR2 Antibodies) genes are responsible for unusual Charcot-Marie-Tooth disease phenotypes.

  5. In this review, periaxin protein is required for the maintenance of peripheral nerve myelin; however, patients with PRX (show PRDX6 Antibodies) mutations have early-onset autosomal recessive demyelinating Charcot-Marie-Tooth disease or Dejerine-Sottas neuropathy.

  6. Results indicate a prominent sensory neuropathy resulting from periaxin gene mutations and suggests a role for the carboxyl terminal domain of the periaxin protein.

  7. Periaxin mutation causes early-onset but slow-progressive Charcot-Marie-Tooth disease

  8. S399fsX410 mutation in the PRX (show PRDX6 Antibodies) gene and its effects at the protein level, which was identified in an 8-year-old patient with early-onsetCharcot-Marie-Tooth type 4F disease.

  9. A PRX (show PRDX6 Antibodies) mutation in Japanese patients is presented.

  10. Data show that the mutations in the periaxin (PRX) gene is associated with early-onset demyelinating AR-CMT and severe sensory loss.

Mouse (Murine) Periaxin (PRX) interaction partners

  1. Taken together, these observations reveal that AnkB (show ANKH Antibodies) is required for Prx membrane anchoring and for maintenance of lens fiber cell hexagonal geometry, membrane skeleton organization, and biomechanics.

  2. Cajal band appositions contain a dystroglycan (show DAG1 Antibodies) complex that includes periaxin and dystrophin (show DMD Antibodies)-related protein (Drp)2 (show DRP2 Antibodies).

  3. Periaxin is required for hexagonal geometry and membrane organization of mature lens fibers

  4. dual mechanism for periaxin regulation and suggest that the role of Krox-20 (show EGR2 Antibodies) is to amplify an earlier Krox-20 (show EGR2 Antibodies)-independent activation of the periaxin genein schwann cells

  5. Preterminal branching due to segmental demyelination near the neuromuscular synapse in Periaxin KO mice may underlie some characteristics of disabilities, including coordination deficits, present in this mouse model of CMT disease.

Periaxin (PRX) Antigen Profile

Protein Summary

This gene encodes a protein involved in peripheral nerve myelin upkeep. The encoded protein contains 2 PDZ domains which were named after PSD95 (post synaptic density protein), DlgA (Drosophila disc large tumor suppressor), and ZO1 (a mammalian tight junction protein). Two alternatively spliced transcript variants have been described for this gene which encode different protein isoforms and which are targeted differently in the Schwann cell. Mutations in this gene cause Charcot-Marie-Tooth neuoropathy, type 4F and Dejerine-Sottas neuropathy.

Gene names and symbols associated with anti-Periaxin (PRX) Antibodies

  • periaxin (prx) antibody
  • periaxin (PRX) antibody
  • periaxin (Prx) antibody
  • CMT4F antibody
  • L-Periaxin antibody
  • MGC89167 antibody
  • xprx antibody

Protein level used designations for anti-Periaxin (PRX) Antibodies

periaxin

GENE ID SPECIES
448336 Xenopus (Silurana) tropicalis
484501 Canis lupus familiaris
737729 Pan troglodytes
100017743 Monodelphis domestica
100389887 Callithrix jacchus
100445415 Pongo abelii
57716 Homo sapiens
19153 Mus musculus
78960 Rattus norvegicus
100626438 Sus scrofa
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