anti-Perilipin 1 (PLIN1) Antibodies

The protein encoded by PLIN1 coats lipid storage droplets in adipocytes, thereby protecting them until they can be broken down by hormone-sensitive lipase. Additionally we are shipping PLIN1 Kits (28) and PLIN1 Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PLIN1 5346 O60240
PLIN1 103968 Q8CGN5
PLIN1 25629 P43884
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Top anti-PLIN1 Antibodies at antibodies-online.com

Showing 10 out of 122 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-PLIN Antibody Titration: 1.25ug/mlPositive Control: Jurkat cell lysate WB Suggested Anti-PLIN  Antibody Titration: 1.25 µg/mL  Positive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Goat Un-conjugated ELISA, WB ABIN190817 (0.01µg/ml) staining of Human Adipose lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. ABIN190817 staining of differentiated 3T3-L1 adipocytes. Data kindly provided by Prof. J. Granneman, Detroit, USA 100 μg Log in to see 6 to 7 Days
$326.89
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB Detection of Perilipin in human liver samples using ABIN258311 (2ug/ml). Western Blot: Perilipin Antibody [ABIN2583110] - Total protein from Human breast (lane 1), Human adipose membrane fraction (lane 2) and Human adipose tissue (lane 3) were separated on a 12% gel by SDS-PAGE. Protein was transferred to PVDF membrane, probed with 2 ug/ml anti-perilipin antibody followed by anti-rabbit HRP conjugated secondary antibody and detected with chemiluminescence. 0.1 mL Log in to see 7 to 9 Days
$408.19
Details
Human Goat Un-conjugated ELISA, WB ABIN190818 (0.01µg/ml) staining of Human Adipose lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 6 to 7 Days
$326.89
Details
Human Goat Un-conjugated ELISA, ICC, IF, IHC, IHC (fro), IHC (p), WB Western Blot: Perilipin (C Terminus) Antibody [ABIN253096] - ABIN253096(0.01ug/ml) staining of Human Adipose lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. ABIN253096 staining of differentiated 3T3-L1 adipocytes. Data kindly provided by Prof. J. Granneman, Detroit, USA 0.1 mg Log in to see 7 to 9 Days
$447.56
Details
Cow Guinea Pig Un-conjugated IHC (fro), IHC (p), WB   0.1 mL Log in to see 6 to 8 Days
$489.50
Details
Cow Guinea Pig Un-conjugated IHC (fro), IHC (p), WB   0.1 mL Log in to see 6 to 8 Days
$500.50
Details
Cow Mouse Un-conjugated IHC (fro), IF, IHC (p), WB   5 mL Log in to see 6 to 8 Days
$368.50
Details
Dog Goat Un-conjugated IF, IHC (fro), IHC (p), WB   0.1 mg Log in to see 12 to 15 Days
$375.38
Details
Dog Goat Un-conjugated EIA, IHC (p), WB Human Colon (formalin-fixed, paraffin-embedded) stained with PLINat 4 µg/ml followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. Antibody (0.01 µg/ml) staining of Human Adipose lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 50 μg Log in to see 6 to 8 Days
$500.50
Details

PLIN1 Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-PLIN1 Antibodies

  1. Cow (Bovine) Polyclonal PLIN1 Primary Antibody for IHC (fro), IHC (p) - ABIN113463 : Heid, Moll, Schwetlick, Rackwitz, Keenan: Adipophilin is a specific marker of lipid accumulation in diverse cell types and diseases. in Cell and tissue research 1998 (PubMed)
    Show all 6 references for 113463

  2. Human Polyclonal PLIN1 Primary Antibody for ELISA, ICC - ABIN253096 : Rigamonti, Brennand, Lau, Cowan: Rapid cellular turnover in adipose tissue. in PLoS ONE 2011 (PubMed)
    Show all 5 references for 253096

  3. Human Polyclonal PLIN1 Primary Antibody for ICC, IF - ABIN258311 : Kadereit, Kumar, Wang, Miranda, Snapp, Severina, Torregroza, Evans, Silver: Evolutionarily conserved gene family important for fat storage. in Proceedings of the National Academy of Sciences of the United States of America 2008 (PubMed)
    Show all 3 references for 258311

  4. Cow (Bovine) Monoclonal PLIN1 Primary Antibody for IHC (fro), IF - ABIN452158 : Blanchette-Mackie, Dwyer, Barber, Coxey, Takeda, Rondinone, Theodorakis, Greenberg, Londos: Perilipin is located on the surface layer of intracellular lipid droplets in adipocytes. in Journal of lipid research 1995 (PubMed)
    Show all 2 references for 452158

  5. Human Polyclonal PLIN1 Primary Antibody for ELISA, WB - ABIN190817 : Wolins, Brasaemle, Bickel: A proposed model of fat packaging by exchangeable lipid droplet proteins. in FEBS letters 2006 (PubMed)

  6. Cow (Bovine) Polyclonal PLIN1 Primary Antibody for WB - ABIN2777126 : Moore, Silver, Mottillo, Bernlohr, Granneman: Perilipin targets a novel pool of lipid droplets for lipolytic attack by hormone-sensitive lipase. in The Journal of biological chemistry 2005 (PubMed)

More Antibodies against PLIN1 Interaction Partners

Human Perilipin 1 (PLIN1) interaction partners

  1. The PLIN 6 polymorphism of the perilipin gene may influence the risk of obesity during adolescence.

  2. Variability at the PLIN1 locus is associated with variability in weight loss. Moreover, eating late is related to lower weight-loss effectiveness among carriers of the AA genotype at the PLIN1 14995A>T variant.

  3. The strong association of PLIN1, CFD (show CFD Antibodies) and ADIPOQ (show ADIPOQ Antibodies) genes with adipogenesis prompted authors to study the influence the bone health status as evaluated by quantitative ultrasound (QUS) bone densitometer in a North Indian cohort. Overall, ADIPOQ (show ADIPOQ Antibodies) (rs1501299 and rs3774261) and combined cluster of PLIN1 rs2304796 and rs2304795) and CFD (show CFD Antibodies) (rs1683563) demonstrated correlation.

  4. Perilipin 1 expression increased with adipocytic differentiation of liposarcoma subtypes showing statistical significance.

  5. Based on the PCR with mismatched primers PLIN1 polymorphisms could be identified effectively in Chinese Han population.

  6. Conserved amphipathic helices mediate lipid droplet targeting of PLIN1, PLIN2 (show PLIN2 Antibodies), and PLIN3 (show PLIN3 Antibodies).

  7. Skeletal muscle PLIN proteins likely play a role in the hydrolysis of triglycerides stored in lipid droplets and the passage of fatty acids to the mitochondria for oxidation.

  8. The functional PLIN1 rs6496589 may influence the risk of central obesity through possible regulation of lipid storage.

  9. After bariatric surgery-induced weight loss, PLIN1 gene/protein expression in SAT increased significantly. Findings suggest a positive functional interaction between PLIN1 & mitochondrial biogenesis-related genes in human adipose tissue.

  10. Use of molecular docking software to design perilipin-1 inhibitors as antiobesity agents.

Cow (Bovine) Perilipin 1 (PLIN1) interaction partners

  1. Perilipin, which was thought to be characteristic for lipid droplets of adipocytes and steroidogenic cells, becomes de novo expressed in hepatocytes of human, mouse, and cattle liver.

Mouse (Murine) Perilipin 1 (PLIN1) interaction partners

  1. ex vivo studies in human primary adipocytes, demonstrate that perilipin 1 binds to AQP7 (show AQP7 Antibodies), and that catecholamine activated protein kinase A phosphorylates the N-terminus of AQP7 (show AQP7 Antibodies), thereby reducing complex formation

  2. Here, we identify synthetic ligands that release ABHD5 (show ABHD5 Antibodies) from PLIN1 or PLIN5 (show PLIN5 Antibodies) without PKA activation and rapidly activate adipocyte and muscle lipolysis.

  3. Heterozygous Plin1+/- SVCs were able to develop lipid droplets, with both the number and size more than in Plin1-/- SVCs but less than in Plin1+/+ SVCs, indicating that Plin1 haploinsufficiency accounts for attenuated adipogenesis.

  4. Plin1 deficiency in bone marrow-derived cells may be responsible for reduced atherosclerotic lesions in the mice

  5. Perilipin+ embryonic preadipocytes actively proliferate along growing vasculatures for adipose expansion.

  6. Data suggest cardiotrophin-1 (show CTF1 Antibodies) up-regulates lipolysis in adipocytes via 1) induction of Plin1, 2) activation of hormone sensitive lipase (show LIPE Antibodies) (via phosphorylation by PKA), and 3) inactivation of adipose triglyceride lipase (show PNPLA2 Antibodies) (via up-regulation of G0S2 (show G0S2 Antibodies)).

  7. Adipocytes of Plin1/ mice showed robust basal lipolysis and fatty acid efflux to the plasma. Such adipose tissue dysfunctions accounted for the ectopic lipid accumulation and enhanced fatty acid transport and oxidation in Plin1/ hearts.

  8. QRFP-43 attenuates lipolysis by preventing the formation of an active complex between perilipin A, caveolin-1 (show CAV1 Antibodies), the catalytic subunit of protein kinase (show CDK7 Antibodies) and hormone-sensitive lipase (show LIPE Antibodies) on lipid droplets.

  9. ESR1 (show ESR1 Antibodies) regulates ATGL (show PNPLA2 Antibodies) and perilipin-mediated lipid metabolism and droplet size in femurs from mice.

  10. Collectively these data suggest that whereas perilipin 1 potently suppresses basal lipolysis in adipocytes, perilipins 2 and 3 facilitate higher rates of basal lipolysis

Pig (Porcine) Perilipin 1 (PLIN1) interaction partners

  1. PLIN1 and PLIN2 (show PLIN2 Antibodies) have been evaluated as candidate genes for growth, carcass and meat quality traits in pigs; two single-nucleotide polymorphisms, one in intron 2 of the PLIN1 gene (JN860199:g.173G>A) and the 3' untranslated region of the PLIN2 (show PLIN2 Antibodies) gene (GU461317:g.98G>A); results obtained indicate that the PLIN2 (show PLIN2 Antibodies) polymorphism could be a useful marker for lean growth.

  2. In pig muscle PLIN1 and PLIN2 (show PLIN2 Antibodies) proteins are localized in correspondence with extra and intra-myocellular lipids, respectively.

  3. This work describes the cloning and sequencing of porcine PLIN and M6PRBP1 (show PLIN3 Antibodies) cDNAs, the chromosome mapping of these two genes, as well as the expression pattern of porcine PAT genes.

PLIN1 Antigen Profile

Protein Summary

The protein encoded by this gene coats lipid storage droplets in adipocytes, thereby protecting them until they can be broken down by hormone-sensitive lipase. The encoded protein is the major cAMP-dependent protein kinase substrate in adipocytes and, when unphosphorylated, may play a role in the inhibition of lipolysis. Alternatively spliced transcript variants varying in the 5' UTR, but encoding the same protein, have been found for this gene.

Gene names and symbols associated with anti-Perilipin 1 (PLIN1) Antibodies

  • perilipin 1 (PLIN1) antibody
  • perilipin 1 (plin1) antibody
  • perilipin (LOC692833) antibody
  • perilipin 1 (Plin1) antibody
  • perilipin-1-like (LOC100856637) antibody
  • 6030432J05Rik antibody
  • FPLD4 antibody
  • LOC692833 antibody
  • Peri antibody
  • PERIA antibody
  • perilipin antibody
  • Plin antibody

Protein level used designations for anti-Perilipin 1 (PLIN1) Antibodies

perilipin , perilipin 1 , perilipin-1-like , lipid droplet-associated protein , perilipin-1 , perilipin A , perilipin B , PERI , adipocyte lipid droplet binding protein

GENE ID SPECIES
467755 Pan troglodytes
594876 Xenopus (Silurana) tropicalis
692833 Bombyx mori
100036810 Xenopus laevis
100407311 Callithrix jacchus
100437952 Pongo abelii
5346 Homo sapiens
520598 Bos taurus
103968 Mus musculus
25629 Rattus norvegicus
654411 Sus scrofa
100135431 Ovis aries
415487 Gallus gallus
488735 Canis lupus familiaris
100728074 Cavia porcellus
100856637 Canis lupus familiaris
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