anti-Peripherin (PRPH) Antibodies

PRPH encodes a cytoskeletal protein found in neurons of the peripheral nervous system. Additionally we are shipping Peripherin Kits (13) and Peripherin Proteins (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PRPH 5630 P41219
PRPH 19132  
PRPH 24688  
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Top anti-Peripherin Antibodies at

Showing 10 out of 128 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB <b>WB Suggested Anti-PRPH Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>Human heart 100 μL Log in to see 2 to 3 Days
Cow Rabbit Un-conjugated WB <b>WB Suggested Anti-PRPH Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:1562500<br><b>Positive Control: </b>HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
Human Rabbit Un-conjugated IHC, ELISA, WB Western blot analysis of extracts from HepG2 cells, using Peripherin Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human brain tissue, using Peripherin Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
Human Rabbit Un-conjugated ICC, IHC (fro), IF, IHC (p), IHC, ELISA, WB Detection of the 57 kDa peripherin protein in whole rat brain stem homogenate using ABIN152483 (1:20,000).  The faint 48 kDa band is a peripherin molecule. 0.1 mL Log in to see 7 to 9 Days
Bat Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
Human Mouse Un-conjugated ICC, IF, ELISA, WB   0.5 mL Log in to see 7 to 9 Days
Human Rabbit Un-conjugated WB WB Image Sample (30 ug of whole cell lysate) A: Hela 10% SDS PAGE Peripherin antibody antibody diluted at 1:1000 100 μL Log in to see 1 to 2 Days
Dog Chicken Un-conjugated IF, WB Rat mixed neuron/glial cultures stained with Peripherin antibody (Green channel) and Neurofilament alpha-internexin/NF66 antibody (green channel). These cultures contain mostly neurons which are rich in alpha-internexin, and a subgroup which have a large amount of peripherin also, such as the prominent cell in the middle of the micrograph. Since this cell expresses large amounts of peripherin and alpha-internexin, the green and red signals superimpose to produce a golden cell. Blue is a DNA stain. 0.1 mL Log in to see 6 to 8 Days
Bat Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
Human Rabbit Un-conjugated IHC, WB Western blot analysis of extracts of various cells, using PRPH antibody. Immunohistochemistry of paraffin-embedded rat heart using PRPH antibody at dilution of 1:100 (x40 lens). 100 μL Log in to see 16 Days

PRPH Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , , ,
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Mouse (Murine) , ,
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Rat (Rattus) ,
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Top referenced anti-Peripherin Antibodies

  1. Human Polyclonal Peripherin Primary Antibody for ICC, IHC (fro) - ABIN152483 : Burgess, Jucius, Ackerman: Motor axon guidance of the mammalian trochlear and phrenic nerves: dependence on the netrin receptor Unc5c and modifier loci. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2006 (PubMed)
    Show all 5 Pubmed References

  2. Polyclonal Peripherin Primary Antibody for IHC (fro), IF - ABIN540386 : Arvanian, Bowers, Petruska, Motin, Manuzon, Narrow, Federoff, Mendell: Viral delivery of NR2D subunits reduces Mg2+ block of NMDA receptor and restores NT-3-induced potentiation of AMPA-kainate responses in maturing rat motoneurons. in Journal of neurophysiology 2004 (PubMed)
    Show all 3 Pubmed References

  3. Human Monoclonal Peripherin Primary Antibody for ICC, IF - ABIN152484 : Errante, Wiche, Shaw: Distribution of plectin, an intermediate filament-associated protein, in the adult rat central nervous system. in Journal of neuroscience research 1994 (PubMed)

  4. Human Polyclonal Peripherin Primary Antibody for IHC, ELISA - ABIN1533379 : Sekino, Nakano, Hamaue, Chuganji, Sakamoto, Yoshimura, Origuchi, Okita: Sensory hyperinnervation and increase in NGF, TRPV1 and P2X3 expression in the epidermis following cast immobilization in rats. in European journal of pain (London, England) 2014 (PubMed)

More Antibodies against Peripherin Interaction Partners

Human Peripherin (PRPH) interaction partners

  1. To discover of Phosphorylated autoantigens Peripherin as a Major Humoral Autoantigen in Type 1 Diabetes Mellitus.

  2. In patients with HD, a panel using calretinin and peripherin with or without MAP-2 may be most helpful in identifying transition zones

  3. interaction between disease-causing RAB7A (show RAB7A Antibodies) mutants and peripherin could play an important role in Charcot-Marie-Tooth type 2B neuropathy

  4. This work contributes to determine the role of PRPH gene variants in ALS. Further studies are necessary to define the mechanisms through which the mutant peripherin could cause ALS phenotype.

  5. study analyzed expression of peripherin(PP) in the cochlea; in organ of Corti, PP seems to be specifically expressed in outer hair cell afferents; small or type II spiral ganglion cell bodies also intensely express PP

  6. although the mechanisms underlying peripherin co-localization in Bunina bodies are unknown, peripherin could be involved in forming these inclusions

  7. Transgenic peripherin isoform expression reveals post-transcriptional changes to the normal expression pattern associated with malformed filaments and intracellular inclusions underlying a role in the pathogenesis of amyotrophic lateral sclerosis.

  8. The data of this experiment document the expression of peripherin in Lewy body-like inclusions , which may provide a clue to the pathogenesis of neurodegeneration in ALS.

  9. Peripherin overexpression in transgenic mice can cause defective transport of type IV neurofilament proteins, a phenomenon that may account for the progressive formation of amyotrophic lateral sclerosis-like spheroids in axons.

  10. peripherin is a novel substrate for Akt (show AKT1 Antibodies) in vivo and its phosphorylation may play a role in motor nerve regeneration

Mouse (Murine) Peripherin (PRPH) interaction partners

  1. ablation of Rom1 (show ROM1 Antibodies) results in the conversion of an MD/PD phenotype characterized by cone functional defects and the formation of abnormal Prph2 (show PRPH2 Antibodies)/Rom1 (show ROM1 Antibodies) complexes to an RP phenotype characterized by rod-dominant functional defects and reductions in total Prph2 (show PRPH2 Antibodies) protein. Thus one method by which ROM1 (show ROM1 Antibodies) may act as a disease modifier is by contributing to the large variability in PRPH2 (show PRPH2 Antibodies)-associated disease phenotype

  2. quantitative FRET analysis in acutely isolated cone OS revealed that the cone degeneration-causing V268I mutation in peripherin-2 (show PRPH2 Antibodies) selectively reduced binding to M-opsin without affecting the peripherin-2 (show PRPH2 Antibodies) interaction to S-opsin (show OPN1SW Antibodies) or rhodopsin (show RHO Antibodies)

  3. These results support the idea that mutations may differentially affect Prph2 (show PRPH2 Antibodies)'s role as a structural component, and its role as a functional protein key for organizing membrane domains for cellular signalling. These roles may be different in rods and cones, thus contributing to the phenotypic heterogeneity that characterizes diseases associated with Prph2 (show PRPH2 Antibodies) mutations.

  4. Data suggest that the underlying molecular mechanisms in amyotrophic lateral sclerosis pathogenesis involve peripherin mis (show AMH Antibodies)-splicing and altered homeostasis of nerve fibers.

  5. Eliminating Cngb1 (show CNGB1 Antibodies) and reducing RDS (show PRPH2 Antibodies) leads to additive defects in RDS (show PRPH2 Antibodies) expression levels and rod electroretinogram (ERG (show ERG Antibodies)) function, (e.g., Cngb1 (show CNGB1 Antibodies)-/-/rds (show PRPH2 Antibodies)+/- versus rds (show PRPH2 Antibodies)+/- or Cngb1 (show CNGB1 Antibodies)-/-) but not to additive defects in rod ultrastructure.

  6. In the group of mice manifesting homozygous mutation in the PRPH2 (show PRPH2 Antibodies) gene.

  7. Our data suggest that upregulation of PRPH2 (show PRPH2 Antibodies) levels in combination with defects in the PRPH2 (show PRPH2 Antibodies) function caused by the mutation might be an important mechanism leading to cone degeneration.

  8. Contralateral and ipsilateral olivocochlear efferent-mediated suppression of the cochlear amplifier were absent in Prph null mice.

  9. These data suggest that glycosylation of RDS (show PRPH2 Antibodies) is required for RDS (show PRPH2 Antibodies) function or stability in cones, a difference that may be due to extracellular versus intradiscal localization of the RDS (show PRPH2 Antibodies) glycan in cones versus rods.

  10. Peripherin-2 (show PRPH2 Antibodies) links CNGB1 (show CNGB1 Antibodies) to the light-detector rhodopsin (show RHO Antibodies) in outer segments of rod photoreceptors.

Peripherin (PRPH) Antigen Profile

Protein Summary

This gene encodes a cytoskeletal protein found in neurons of the peripheral nervous system. The encoded protein is a type III intermediate filament protein with homology to other cytoskeletal proteins such as desmin, and is a different protein that the peripherin found in photoreceptors. Mutations in this gene have been associated with susceptibility to amyotrophic lateral sclerosis.

Gene names and symbols associated with anti-Peripherin (PRPH) Antibodies

  • peripherin (PRPH) antibody
  • peripherin (prph) antibody
  • peripherin (Prph) antibody
  • peripherin L homeolog (prph.L) antibody
  • peripherin 2 (Prph2) antibody
  • AOFMD antibody
  • AVMD antibody
  • if3 antibody
  • MGC69454 antibody
  • NEF4 antibody
  • Nmf193 antibody
  • Perf antibody
  • plasticin antibody
  • PRPH antibody
  • Prph1 antibody
  • Rd-2 antibody
  • Rd2 antibody
  • rds antibody
  • RP7 antibody
  • Tspan22 antibody

Protein level used designations for anti-Peripherin (PRPH) Antibodies

peripherin , peripherin 1 , neurofilament 4 (57kD) , neuronal intermediate filament IF3 , peripherin-2 , retinal degeneration 2 , retinal degeneration slow protein , retinal degeneration, slow (retinitis pigmentosa 7)

100059208 Equus caballus
407916 Xenopus (Silurana) tropicalis
5630 Homo sapiens
510082 Bos taurus
19132 Mus musculus
24688 Rattus norvegicus
477618 Canis lupus familiaris
100152434 Sus scrofa
380221 Xenopus laevis
100357822 Oryctolagus cuniculus
101082247 Felis catus
19133 Mus musculus
Selected quality suppliers for anti-Peripherin (PRPH) Antibodies
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