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Periphilin 1 Proteins (PPHLN1)

The protein encoded by PPHLN1 is one of the several proteins that become sequentially incorporated into the cornified cell envelope during the terminal differentiation of keratinocyte at the outer layers of epidermis. Additionally we are shipping PPHLN1 Antibodies (47) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PPHLN1 51535 Q8NEY8
PPHLN1 223828 Q8K2H1
Rat PPHLN1 PPHLN1 366975  
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Top PPHLN1 Proteins at antibodies-online.com

Showing 4 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

PPHLN1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for Periphilin 1 (PPHLN1) Interaction Partners

Human Periphilin 1 (PPHLN1) interaction partners

  1. analysis of FGFR2 (show FGFR2 Proteins)-PPHLN1 fusion and ARAF (show ARAF Proteins) mutations in intrahepatic cholangiocarcinoma

  2. this study identified the HUSH (human silencing hub) complex, comprising three poorly characterized proteins, TASOR, MPP8 (show MPHOSPH8 Proteins), and periphilin; this complex is absent from Drosophila but is conserved from fish to humans.

  3. Data show that periphilin displays an overlapping expression pattern with synphilin-1 (show SNCAIP Proteins) in cellular and animal models and in Lewy bodies of Parkinson's disease (PD) patients, and support involvement of periphilin in PD.

  4. periphilin is potentially involved in epithelial differentiation and contributes to epidermal integrity and barrier formation

  5. CR (periphilin) retards S-phase progression by modifying expression of Cdc7 (show CDC7 Proteins) and other genes involved in progression of DNA replication

Mouse (Murine) Periphilin 1 (PPHLN1) interaction partners

  1. results point to an indispensable function of periphilin during murine development and an important role in the nervous system, reflected by a strong and tightly regulated expression in the murine brain.

PPHLN1 Protein Profile

Protein Summary

The protein encoded by this gene is one of the several proteins that become sequentially incorporated into the cornified cell envelope during the terminal differentiation of keratinocyte at the outer layers of epidermis. This protein interacts with periplakin, which is known as a precursor of the cornified cell envelope. The cellular localization pattern and insolubility of this protein suggest that it may play a role in epithelial differentiation and contribute to epidermal integrity and barrier formation. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.

Gene names and symbols associated with Periphilin 1 Proteins (PPHLN1)

  • periphilin 1 (PPHLN1)
  • periphilin 1 (pphln1)
  • periphilin 1 (LOC100354943)
  • periphilin 1 (Pphln1)
  • 1110063K05Rik protein
  • 1600022A19Rik protein
  • CR protein
  • HSPC206 protein
  • HSPC232 protein
  • MGC75908 protein
  • MGC81987 protein
  • si:ch211-155a11.2 protein
  • wu:fb83c09 protein
  • zgc:158246 protein

Protein level used designations for Periphilin 1 Proteins (PPHLN1)

periphilin 1 , periphilin-1 , periphilin-1-like , gastric cancer antigen Ga50

GENE ID SPECIES
100054208 Equus caballus
394576 Xenopus (Silurana) tropicalis
417792 Gallus gallus
444783 Xenopus laevis
451837 Pan troglodytes
790935 Danio rerio
100409397 Callithrix jacchus
100354943 Oryctolagus cuniculus
51535 Homo sapiens
223828 Mus musculus
366975 Rattus norvegicus
477639 Canis lupus familiaris
532695 Bos taurus
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