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anti-Periplakin (PPL) Antibodies

The protein encoded by PPL is a component of desmosomes and of the epidermal cornified envelope in keratinocytes. Additionally we are shipping Periplakin Kits (7) and Periplakin Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PPL 5493 O60437
PPL 302934  
PPL 19041 Q9R269
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Top anti-Periplakin Antibodies at antibodies-online.com

Showing 10 out of 44 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-PPL Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62... 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), WB PPL Antibody (C-term) (ABIN658092) western blot analysis in T47D cell ... 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated WB Periplakin antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 3 to 4 Days
$473.93
Details
Cow Guinea Pig Un-conjugated IHC (fro), IF, IP, WB   0.1 mL Log in to see 6 to 8 Days
$478.50
Details
Human Rabbit Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Log in to see 9 to 11 Days
$385.00
Details
Mouse Rabbit Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Log in to see 9 to 11 Days
$396.00
Details
Human Rabbit APC IHC, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated IHC, WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit Un-conjugated IHC, ELISA, WB   200 μL Log in to see 11 to 16 Days
$532.71
Details

PPL Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , , , ,
,
Rat (Rattus)
Mouse (Murine) , , , ,

Top referenced anti-Periplakin Antibodies

  1. Human Polyclonal PPL Primary Antibody for WB - ABIN2777127 : Boczonadi, McInroy, Määttä: Cytolinker cross-talk: periplakin N-terminus interacts with plectin to regulate keratin organisation and epithelial migration. in Experimental cell research 2007 (PubMed)

  2. Cow (Bovine) Polyclonal PPL Primary Antibody for IHC (fro), IF - ABIN401679 : Straub, Boda, Kuhn, Schnoelzer, Korf, Kempf, Spring, Hatzfeld, Franke: A novel cell-cell junction system: the cortex adhaerens mosaic of lens fiber cells. in Journal of cell science 2003 (PubMed)

More Antibodies against Periplakin Interaction Partners

Human Periplakin (PPL) interaction partners

  1. Low serum periplakin is associated with urothelial carcinoma.

  2. Human gamma-delta T cells are activated by cytosolic interactions of BTN3A1 (show BTN3A1 Antibodies) with soluble phosphoantigens and the cytoskeletal adaptor periplakin.

  3. Loss of periplakin expression is associated with pathological stage and cancer-specific survival in patients with urothelial carcinoma of the urinary bladder.

  4. Annexin A9 (show ANXA9 Antibodies) and periplakin co-localise in the epidermis and annexin A9 (show ANXA9 Antibodies) is up-regulated in differentiating keratinocytes, but the epidermal annexin A9 (show ANXA9 Antibodies) expression does not require periplakin.

  5. Sciellin (show SCEL Antibodies), SPRR3 (show SPRR3 Antibodies), and periplakin transcripts were all upregulated (4.67-, 4.95-, 2.77-fold, respectively) by prolonged exposure to cyclic strain (24-72 h), but not at earlier time points.

  6. autoantibodies are detected in patients with paraneoplastic pemphigus

  7. This protein binds to protein kinase B (show AKT1 Antibodies).

  8. in spite of its high homology and structural similarity with envoplakin (show EVPL Antibodies), periplakin is functionally closer to the plakin proteins plectin (show PLEC Antibodies) and desmoplakin (show DSP Antibodies), and may function tissue-wide as a scaffolding protein in intermediate filament assembly

  9. interactions between helix VIII of the human mu-opioid receptors and the C terminus of periplakin disrupt G protein activation

  10. envoplakin (show EVPL Antibodies) and periplakin bind to the plasma membrane upon elevation of intracellular [Ca(2 (show CA2 Antibodies)+)] in differentiating keratinocytes, where they serve as a scaffold for cornified cell envelope assembly

Mouse (Murine) Periplakin (PPL) interaction partners

  1. Data suggest that the primary role of periplakin may not relate to the physiology of the cornified cell envelope in epidermal keratinocytes but may reside in the challenges, which normal laboratory mice do not encounter.

  2. Periplakin interferes with G protein activation by the melanin-concentrating hormone receptor-1 (show MCHR1 Antibodies) by binding to the proximal segment of the receptor C-terminal tail

Periplakin (PPL) Antigen Profile

Protein Summary

The protein encoded by this gene is a component of desmosomes and of the epidermal cornified envelope in keratinocytes. The N-terminal domain of this protein interacts with the plasma membrane and its C-terminus interacts with intermediate filaments. Through its rod domain, this protein forms complexes with envoplakin. This protein may serve as a link between the cornified envelope and desmosomes as well as intermediate filaments. AKT1/PKB, a protein kinase mediating a variety of cell growth and survival signaling processes, is reported to interact with this protein, suggesting a possible role for this protein as a localization signal in AKT1-mediated signaling.

Gene names and symbols associated with anti-Periplakin (PPL) Antibodies

  • periplakin (PPL) antibody
  • periplakin (ppl) antibody
  • periplakin (LOC100343940) antibody
  • periplakin (Ppl) antibody
  • AW553870 antibody
  • cb180 antibody
  • im:7140067 antibody
  • im:7149519 antibody
  • sb:cb180 antibody

Protein level used designations for anti-Periplakin (PPL) Antibodies

periplakin , periplakin-like , 190 kDa paraneoplastic pemphigus antigen , 195 kDa cornified envelope precursor protein , 195kDa protein

GENE ID SPECIES
408044 Gallus gallus
449936 Danio rerio
453893 Pan troglodytes
490021 Canis lupus familiaris
495053 Xenopus laevis
710266 Macaca mulatta
100069951 Equus caballus
100343940 Oryctolagus cuniculus
100407595 Callithrix jacchus
100460826 Pongo abelii
100512773 Sus scrofa
100547953 Meleagris gallopavo
100563033 Anolis carolinensis
100602203 Nomascus leucogenys
5493 Homo sapiens
522886 Bos taurus
302934 Rattus norvegicus
19041 Mus musculus
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