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Drosophila peroxidasin is an extracellular matrix-associated peroxidase (Horikoshi et al., 1999 [PubMed 10441517]). Additionally we are shipping PXDN Antibodies (18) and PXDN Kits (11) and many more products for this protein.
Showing 7 out of 12 products:
PXDN expression is significantly upregulated in human masticatory mucosa during wound healing
Novel mutations in PXDN cause microphthalmia and anterior segment dysgenesis
Despite sequence homology at the active site and biophysical properties similar to human peroxidases, the catalytic efficiency of bromide oxidation (kcat/KM(app (show APP Proteins))) of full-length hsPxd01 is rather low but increased upon truncation.
MiR (show MLXIP Proteins)-4782-3p inhibited cell proliferation in NSCLC by targeting USP14 (show USP14 Proteins), ZEB2 and XIAP (show XIAP Proteins).
studies demonstrate the enzymatic properties and substrate specificity of VPO1 are similar to MPO (show MPO Proteins); however, significantly lower catalytic rate constants of VPO1 relative to MPO (show MPO Proteins) suggest the possibility of other physiologic roles for this peroxidase
VPO1 is likely to participate in host defense, with bactericidal activity mediated through the generation of HOCl.
Results from this study indicate that the 2p25.3 duplication disrupting PXDN and MYT1L is a potential autism-causing variant in the pedigree reported here and should receive further consideration as a candidate for autism
Vascular peroxidase-1 is rapidly secreted, circulates in plasma, and supports dityrosine cross-linking reactions.
Homozygous mutations in PXDN cause congenital cataract, corneal opacity, and developmental glaucoma.
Cdkn1b (show CDKN1B Proteins) exert its effects via the inhibition of proliferation and is mediated by miR (show MLXIP Proteins)-24 and targeted by the transcription factors FOXO4 (show FOXO4 Proteins) and AP4 (show REPIN1 Proteins) in the peroxidasin (Pxdn) mutation-induced eye disorders, such as glaucoma.
Drosophila peroxidasin is an extracellular matrix-associated peroxidase (Horikoshi et al., 1999
melanoma-associated antigen MG50
, p53-responsive gene 2 protein
, peroxidasin homolog
, vascular peroxidase 1