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Peroxiredoxin 2 Proteins (PRDX2)

PRDX2 encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. Additionally we are shipping Peroxiredoxin 2 Antibodies (138) and Peroxiredoxin 2 Kits (36) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PRDX2 7001 P32119
PRDX2 21672 Q61171
PRDX2 29338 P35704
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Top Peroxiredoxin 2 Proteins at antibodies-online.com

Showing 10 out of 32 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Baculovirus infected Insect Cells Human His tag 100 μg Log in to see 16 Days
$437.80
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated 100 μg Log in to see 2 to 3 Days
$367.50
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated 100 μg Log in to see 7 to 8 Days
$407.00
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated Figure annotation denotes ug of protein loaded and % gel used. 100 μg Log in to see 7 to 9 Days
$467.86
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 11 to 13 Days
$704.00
Details
HOST_Escherichia coli (E. coli) Mouse His tag 100 μg Log in to see 11 to 13 Days
$771.10
Details
HOST_Escherichia coli (E. coli) Rat His tag 100 μg Log in to see 11 to 13 Days
$792.00
Details

PRDX2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, ,
Mouse (Murine)

Rat (Rattus) ,

Top referenced Peroxiredoxin 2 Proteins

  1. Human Peroxiredoxin 2 Protein expressed in Baculovirus infected Insect Cells - ABIN2004159 : Cha, Kim: Thioredoxin-linked peroxidase from human red blood cell: evidence for the existence of thioredoxin and thioredoxin reductase in human red blood cell. in Biochemical and biophysical research communications 1996 (PubMed)
    Show all 4 references for ABIN2004159

  2. Human Peroxiredoxin 2 Protein expressed in Escherichia coli (E. coli) - ABIN667730 : Kim, Yu, Han, Oh, Choi, Kim, Yoon, Jung, Choe: Expression of human peroxiredoxin isoforms in response to cervical carcinogenesis. in Oncology reports 2009 (PubMed)
    Show all 2 references for ABIN667730

  3. Human Peroxiredoxin 2 Protein expressed in Wheat germ - ABIN1316151 : Desmetz, Bascoul-Mollevi, Rochaix, Lamy, Kramar, Rouanet, Maudelonde, Mangé, Solassol: Identification of a new panel of serum autoantibodies associated with the presence of in situ carcinoma of the breast in younger women. in Clinical cancer research : an official journal of the American Association for Cancer Research 2009 (PubMed)

More Proteins for Peroxiredoxin 2 (PRDX2) Interaction Partners

Human Peroxiredoxin 2 (PRDX2) interaction partners

  1. Data show the protein partners of human Prx1 (show PRDX1 Proteins) and Prx2 and identified three sequence motifs, or combination thereof in Prxs partners, namely: CXXC, PXXP, and LXXLL. that can be important for protein localization, function and biological pathways. [review]

  2. Oxidative stress promotes PRX2 and PRX3 (show PRDX3 Proteins) hyperoxidation and attenuates pro-survival signaling in aging chondrocytes.

  3. Prx2 glutathionylation is a favorable reaction that can occur in cells under oxidative stress and may have a role in redox signaling. GSH/Grx1 (show GRX1 Proteins) provide an alternative mechanism to thioredoxin (show TXN Proteins) and thioredoxin reductase (show PRDX5 Proteins) for Prx2 recycling.

  4. the species with one disulfide and one hyperoxidized active site was decameric for Prx2 and dimeric for Prx3 (show PRDX3 Proteins). Reduction and re-oxidation of the hyperoxidized dimer of Prx3 (show PRDX3 Proteins) produced hyperoxidized monomers

  5. Functional roles of catalase (show CAT Proteins), PRDX2 and GPX1 (show GPX1 Proteins) during oxidative stress in human erythrocytes.

  6. Further conclusion showed that Prdx2 regulates VM formation by targeting VEGFR2 (show KDR Proteins) activation, which now represents as a therapeutic target for RC.

  7. Prx (show PRDX6 Proteins) II has an important role in cancer cell survival via the modulation of signaling molecules involved in apoptosis and the phosphorylation of JNK (show MAPK8 Proteins) by the downregulation of reactive oxygen species levels in A549/GR cells.

  8. Reported increased expression of ALDH3A1 (show ALDH3A1 Proteins), PDIA3 (show PDIA3 Proteins), and PRDX2 in pterygia using a proteomic approach. These proteins are presumed to have a protective role against oxidative stress-induced (show SQSTM1 Proteins) apoptosis.

  9. Prx-2 activity is compromised during red blood cell storage.

  10. two placental proteins, Prx3 (show PRDX3 Proteins) and Prx4 (show PRDX4 Proteins), may act as new placental immune targets.

Mouse (Murine) Peroxiredoxin 2 (PRDX2) interaction partners

  1. Oxidative stress promotes PRX2 (show PRRX2 Proteins) and PRX3 (show PRDX3 Proteins) hyperoxidation and attenuates pro-survival signaling in aging chondrocytes.

  2. The ventral signal observed for Prdx2 from early stages colocalized with motor neuron markers Isl1 (show ISL1 Proteins)/2 and FoxP1 (show FOXP1 Proteins) and strong ventral signal colocalizing with Isl1 (show ISL1 Proteins)/2 was observed in all rostrocaudal segments of the spinal cord.

  3. Prx2 (show PRRX2 Proteins) glutathionylation is a favorable reaction that can occur in cells under oxidative stress and may have a role in redox signaling. GSH/Grx1 (show GRX1 Proteins) provide an alternative mechanism to thioredoxin (show TXN Proteins) and thioredoxin reductase for Prx2 (show PRRX2 Proteins) recycling.

  4. elevation in hyperoxidized Prxs, notably Prx2 (show PRRX2 Proteins) and Prx3 (show PRDX3 Proteins), was observed in several organs from SOD1 (show SOD1 Proteins)-deficient mice. However, a SOD1 (show SOD1 Proteins) deficiency had no impact on the wheel-running activity of the mice

  5. PrxII functions as a protective antioxidant enzyme against collagen-stimulated platelet activation and platelet-dependent thrombosis

  6. Prx I and Prx II appear to have a tight association with the mechanism underlying the protection of ESC stemness in developing teratomas.

  7. results suggest that inactivation of PrxII is important for the stability of FoxO1 (show FOXO1 Proteins) protein, which subsequently mediates Foxp3 (show FOXP3 Proteins)( ) Treg cell development, thereby attenuating colonic inflammation

  8. PRDX2 neutralizes hydrogen peroxide generated in vivo under the transient hypoxic conditions experienced as erythrocytes pass through the microcirculation.

  9. PRX2 (show PRRX2 Proteins) battles poly(ADP-ribose) polymerase 1 (show PARP1 Proteins)- and p53 (show TP53 Proteins)-dependent prodeath pathways after ischemic injury

  10. These findings suggest that Prx (show PRX Proteins) II plays an important role in preventing hemolytic anemia from oxidative stress by binding to Hb as a decameric structure to stabilize it.

Peroxiredoxin 2 (PRDX2) Protein Profile

Protein Summary

This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein plays an antioxidant protective role in cells, and it may contribute to the antiviral activity of CD8(+) T-cells. The crystal structure of this protein has been resolved to 2.7 angstroms. This protein prevents hemolytic anemia from oxidative stress by stabilizing hemoglobin, thus making this gene a therapeutic target for patients with hemolytic anemia. This protein may have a proliferative effect and play a role in cancer development or progression. Related pseudogenes have been identified on chromosomes 5, 6, 10 and 13.

Gene names and symbols associated with Peroxiredoxin 2 Proteins (PRDX2)

  • peroxiredoxin-2-like (LOC100063348)
  • peroxiredoxin 2 (PRDX2)
  • peroxiredoxin 2 (Prdx2)
  • peroxiredoxin 2 (prdx2)
  • peroxiredoxin-2-like (LOC100856470)
  • AL022839 protein
  • Band-8 protein
  • NKEF-B protein
  • nkefb protein
  • PRP protein
  • prx-2 protein
  • prx2 protein
  • prxii protein
  • PTX1 protein
  • tdpx1 protein
  • TDX1 protein
  • Torin protein
  • TPx protein
  • TPx-B protein
  • tpx1 protein
  • TR protein
  • TSA protein

Protein level used designations for Peroxiredoxin 2 Proteins (PRDX2)

natural killer cell-enhancing factor B , peroxiredoxin-2 , thiol-specific antioxidant 1 , thioredoxin peroxidase 1 , thioredoxin-dependent peroxide reductase 1 , torin , Calpromotin , Prx II-1 , Trx dependent peroxide reductase 1 , protector protein , thiol specific antioxidant protein , thiol-specific antioxidant protein , thioredoxin dependent peroxide reductase 1 , thioredoxin reductase , TSA

GENE ID SPECIES
100063348 Equus caballus
7001 Homo sapiens
21672 Mus musculus
29338 Rattus norvegicus
443840 Xenopus laevis
100512521 Sus scrofa
286793 Bos taurus
100715787 Cavia porcellus
100307046 Ovis aries
100172251 Pongo abelii
100689349 Cricetulus griseus
100856470 Canis lupus familiaris
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