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Peroxiredoxin 4 Proteins (PRDX4)

The protein encoded by PRDX4 is an antioxidant enzyme and belongs to the peroxiredoxin family. Additionally we are shipping Peroxiredoxin 4 Antibodies (101) and Peroxiredoxin 4 Kits (14) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PRDX4 10549 Q13162
PRDX4 53381 O08807
Rat PRDX4 PRDX4 85274 Q9Z0V5
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Top Peroxiredoxin 4 Proteins at antibodies-online.com

Showing 10 out of 22 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$286.00
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated 100 μg Log in to see 2 to 3 Days
$357.00
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 11 to 13 Days
$774.40
Details
HOST_Escherichia coli (E. coli) Mouse His tag 100 μg Log in to see 11 to 13 Days
$792.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human His tag   50 μg Log in to see 5 Days
$522.50
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,592.33
Details
HOST_Escherichia coli (E. coli) Human His tag   1 mg Log in to see 3 to 4 Days
$2,524.50
Details

PRDX4 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

Top referenced Peroxiredoxin 4 Proteins

  1. Human Peroxiredoxin 4 Protein expressed in Escherichia coli (E. coli) - ABIN666967 : Jin, Chae, Rhee, Jeang: Regulatory role for a novel human thioredoxin peroxidase in NF-kappaB activation. in The Journal of biological chemistry 1998 (PubMed)
    Show all 2 references for ABIN666967

More Proteins for Peroxiredoxin 4 (PRDX4) Interaction Partners

Human Peroxiredoxin 4 (PRDX4) interaction partners

  1. Positive Prx 4 expression is significantly correlated with recurrence and shorter disease-free survival in patients with early-stage lung squamous cell carcinoma.

  2. An off-pathway reaction in the Prx4-mediated oxidative protein folding.

  3. Findings suggest that elevated serum Prx4 levels are associated with a higher risk of incident type 2 diabetes

  4. Prx4 is a circulating antioxidant and is independently associated with increased risk of cardiovascular and all-cause mortality in T2DM.

  5. these data suggest an important role of Prdx4 in maintaining insulin (show INS Proteins) levels and improving the ER folding capacity also under conditions of a high insulin (show INS Proteins) requirement.

  6. there is a significant difference in concentration of Prx4 between cardiac arrest patients with good and poor outcome

  7. The structure and function of PRDX4 as well as its sensitivity to hyperoxidation. [Review]

  8. expression of PRDX4 in PCOS ovaries appeared to be mediated through oxidative stress in GCs (show GCLC Proteins). We reported that the deficiency of antioxidant PRDX4 was associated with pathophysiological mechanism of PCOS.

  9. peroxiredoxin IV recycling in the endoplasmic reticulum is much less efficient than in the cytosol or mitochondria, leading to the protection of peroxiredoxin IV from hyperoxidation.

  10. Remarkably, the Prx4-dependent formation of native disulfide bonds was accelerated when PDI was combined with ERp46 or P5, suggesting that PDIs work synergistically to increase the rate and fidelity of oxidative protein folding.

Mouse (Murine) Peroxiredoxin 4 (PRDX4) interaction partners

  1. data provide the first evidence of the beneficial effects of PRDX4 on intestinal function in the reduction of the severity of NAFLD, by ameliorating oxidative stress-induced (show SQSTM1 Proteins) local and systemic injury

  2. The ventral signal observed for Prdx4 from early stages colocalized with motor neuron markers Isl1 (show ISL1 Proteins)/2 and FoxP1 (show FOXP1 Proteins) and the strong ventral signal colocalizing with Isl1 (show ISL1 Proteins)/2 was observed in all rostrocaudal segments of the spinal cord.

  3. Prdx4 dimers generated by hydrogen peroxide metabolism oxidize two cysteine residues within the GDE2 (show GDPD5 Proteins) enzymatic domain, which blocks GDE2 (show GDPD5 Proteins) trafficking to the plasma membrane and prevents GDE2 (show GDPD5 Proteins) neurogeneic function.

  4. PRDX4 may protect against nonalcoholic steatohepatitis and type 2 diabetes by ameliorating oxidative stress-induced (show SQSTM1 Proteins) injury.

  5. data suggest that PRDX4 can be a novel target for glioblastoma multiforme therapies in the future

  6. combined loss-of-function mutations in genes encoding the ER thiol oxidases ERO1alpha, ERO1beta, and PRDX4 compromised the extracellular matrix and interfered with the intracellular maturation of procollagen

  7. Prx IV-L functions as an H(2)O(2) sensor that mediates protein thiol oxidation required for the maturation of spermatozoa in placental mammals.

  8. The results indicate that spermatogenic cells lacking Prx4 are more susceptible to cell death via oxidative damage than their wild-type counterparts.

Peroxiredoxin 4 (PRDX4) Protein Profile

Protein Summary

The protein encoded by this gene is an antioxidant enzyme and belongs to the peroxiredoxin family. The protein is localized to the cytoplasm. Peroxidases of the peroxiredoxin family reduce hydrogen peroxide and alkyl hydroperoxides to water and alcohol with the use of reducing equivalents derived from thiol-containing donor molecules. This protein has been found to play a regulatory role in the activation of the transcription factor NF-kappaB.

Gene names and symbols associated with Peroxiredoxin 4 Proteins (PRDX4)

  • peroxiredoxin 4 (PRDX4)
  • peroxiredoxin 4 (prdx4)
  • peroxiredoxin 4 (Prdx4)
  • AOE37-2 protein
  • AOE372 protein
  • fb59c09 protein
  • MGC79732 protein
  • MGC82793 protein
  • PRDX4 protein
  • PRX-4 protein
  • Prx-iv protein
  • Prx4 protein
  • TRANK protein
  • wu:fb59c09 protein
  • zgc:162938 protein

Protein level used designations for Peroxiredoxin 4 Proteins (PRDX4)

peroxiredoxin 4 , thioredoxin peroxidase , antioxidant enzyme AOE372 , peroxiredoxin IV , peroxiredoxin-4 , prx-IV , thioredoxin peroxidase (antioxidant enzyme) , thioredoxin peroxidase AO372 , thioredoxin-dependent peroxide reductase A0372 , Prx IV

GENE ID SPECIES
418601 Gallus gallus
444345 Xenopus laevis
448526 Xenopus (Silurana) tropicalis
491776 Canis lupus familiaris
741562 Pan troglodytes
10549 Homo sapiens
53381 Mus musculus
85274 Rattus norvegicus
570477 Danio rerio
281999 Bos taurus
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