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Peroxiredoxin 6 Proteins (PRDX6)

The protein encoded by PRDX6 is a member of the thiol-specific antioxidant protein family. Additionally we are shipping Peroxiredoxin 6 Antibodies (144) and Peroxiredoxin 6 Kits (17) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PRDX6 54683 P99029
PRDX6 9588 P30041
PRDX6 94167 O35244
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Top Peroxiredoxin 6 Proteins at antibodies-online.com

Showing 10 out of 29 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 16 Days
$437.80
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated 100 μg Log in to see 2 to 3 Days
$357.00
Details
HOST_Escherichia coli (E. coli) Rat His tag 100 μg Log in to see 11 to 13 Days
$422.40
Details
HOST_Escherichia coli (E. coli) Human His tag   100 μg Log in to see 11 to 13 Days
$492.80
Details
Yeast Mesocricetus auratus His tag   1 mg Log in to see 56 to 66 Days
$2,020.33
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,557.50
Details

PRDX6 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
,
Rat (Rattus) ,
,

Top referenced Peroxiredoxin 6 Proteins

  1. Human Peroxiredoxin 6 Protein expressed in Escherichia coli (E. coli) - ABIN2004161 : Kang, Baines, Rhee: Characterization of a mammalian peroxiredoxin that contains one conserved cysteine. in The Journal of biological chemistry 1998 (PubMed)
    Show all 3 references for ABIN2004161

  2. Human Peroxiredoxin 6 Protein expressed in Escherichia coli (E. coli) - ABIN667123 : Davison, Pennington, Hung, Peng, Rafiq, Ostareck-Lederer, Ostareck, Ardley, Banks, Robinson: Proteomic analysis of increased Parkin expression and its interactants provides evidence for a role in modulation of mitochondrial function. in Proteomics 2009 (PubMed)
    Show all 2 references for ABIN667123

  3. Human Peroxiredoxin 6 Protein expressed in Wheat germ - ABIN1316165 : Jo, Yun, Park, Park, Lee, Cho, Yoo, Lee, Jeong, Kim, Jung, Hwang, Lee, Kim, Han, Hong: Anti-cancer effect of thiacremonone through down regulation of peroxiredoxin 6. in PLoS ONE 2014 (PubMed)

More Proteins for Peroxiredoxin 6 (PRDX6) Interaction Partners

Xenopus laevis Peroxiredoxin 6 (PRDX6) interaction partners

  1. Gene expressionof Prx6 increased during development, especially at stages 33-43 during formation of the lungs.

Mouse (Murine) Peroxiredoxin 6 (PRDX6) interaction partners

  1. AP-3 (show AP3B1 Proteins)-dependent LB targeting is facilitated by protein/protein interaction between LIMP-2/SCARB2 (show SCARB2 Proteins) and PRDX6 in vitro and in vivo

  2. Prdx6 plays a critical role in the repair of peroxidized phospholipids in cell membranes and the recovery of lung cells from peroxidative stress; the peroxidase and PLA(2 (show PLA2G5 Proteins)) activity each contribute to the recovery process.

  3. The ventral signal observed from E12.5 on colocalized with motor neuron markers Isl1 (show ISL1 Proteins)/2 and FoxP1 (show FOXP1 Proteins) and The strong ventral signal colocalizing wtth Isl1 (show ISL1 Proteins)/2 was observed in all rostrocaudal segments of the spinal cord.

  4. PRDX6 has a role in controlling multiple sclerosis by suppressing inflammation and blood brain barrier disruption

  5. PRDX6 has an important role in dopaminergic neurodegeneration of Parkinson's disease.

  6. Our findings suggest that overexpression of peroxiredoxin 6 might promote development of rheumatoid arthritis through NF-kappaB (show NFKB1 Proteins) and AP-1 (show JUN Proteins) activity via the JNK (show MAPK8 Proteins) pathway.

  7. AA (arachidonic acid) as a crucial effector of PRDX6-dependent proliferation and inducer of Src (show SRC Proteins) family kinase activation.

  8. PRDX6 promotes lung tumor development via its mediated and CCL5 (show CCL5 Proteins)-associated activation of the JAK2 (show JAK2 Proteins)/STAT3 (show STAT3 Proteins) pathway.

  9. results suggest that PrdxV is a key mediator contributing to the regulation of LPS/TLR4 (show TLR4 Proteins)-induced immune responses

  10. Data show that adduction of peroxiredoxin-6 sensitizes male C57BL/6 mice to toxicity by acetaminophen.

Human Peroxiredoxin 6 (PRDX6) interaction partners

  1. Prdx6 and its PLA2 (show YWHAZ Proteins) activity have a protective role in donors after brain death livers.

  2. PRDX6 may serve as a biomarker for traumatic brain injury and that autoimmune profiling is a viable strategy for the discovery of novel biomarkers

  3. PRDX6 protects ARPE-19 cells from hydrogen peroxide-induced oxidative stress and apoptosis.

  4. Delivery of a protein transduction domain-mediated Prdx6 protein protected against oxidative stress-evoked neuronal cell death.

  5. AA (arachidonic acid) as a crucial effector of PRDX6-dependent proliferation and inducer of Src (show SRC Proteins) family kinase activation.

  6. High intensity of cytoplasmic Prx VI expression in pretreatment diffuse large B-cell lymphoma samples predicts worse outcome.

  7. overexpression of PRDX6 promotes lung tumor growth via increased glutathione peroxidase (show GPX1 Proteins) and iPLA2 (show PLA2G6 Proteins) activities through the upregulation of the AP-1 (show FOSB Proteins) and JNK (show MAPK8 Proteins) pathways.

  8. Several regions of reduced PRDX6 are in a substantially different conformation from that of the crystal structure of the peroxidase catalytic intermediate. The differences between the two structures likely reflect catalysis-related conformational changes.

  9. our findings indicate that PRDX6 promotes lung tumor growth via increased glutathione peroxidase (show GPX1 Proteins) and iPLA2 (show PLA2G6 Proteins) activities.

  10. decreased levels, combined with higher thiol oxidation (and probable inhibition) of PRDXs (particularly PRDX6), are noted when human sperm function is altered.

Pig (Porcine) Peroxiredoxin 6 (PRDX6) interaction partners

  1. The expression of porcine Prdx6 gene is up-regulated by C/EBPbeta (show CEBPB Proteins) and CREB (show CREB1 Proteins).

  2. The SNP of PRDX6 gene was significantly associated with the intramuscular fat and water moisture.

Cow (Bovine) Peroxiredoxin 6 (PRDX6) interaction partners

  1. study demonstrated involvement of cytosolic and calcium-independent phospholipase A (show HRASLS Proteins)(2) and the contribution of cyclooxygenase-2 (show PTGS2 Proteins) products in E. coli invasion of brain microvascular endothelial cells

  2. dsRNA as well as other agonists of endothelial cells elicit signaling mechanisms that include in part CREB (show CREB1 Proteins) phosphorylation mediated by iPLA2 (show PLA2G6 Proteins).

  3. PRDX6 upregulation in cumulus-oocyte complexes during in vitro maturation is mutually regulated by both cell types.

Peroxiredoxin 6 (PRDX6) Protein Profile

Protein Summary

The protein encoded by this gene is a member of the thiol-specific antioxidant protein family. This protein is a bifunctional enzyme with two distinct active sites. It is involved in redox regulation of the cell\; it can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. It may play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury.

Gene names and symbols associated with Peroxiredoxin 6 Proteins (PRDX6)

  • peroxiredoxin 6 (prdx6)
  • peroxiredoxin 5 (Prdx5)
  • peroxiredoxin 6 (PRDX6)
  • peroxiredoxin 6 (Prdx6)
  • 1-Cys protein
  • 1-cysPrx protein
  • 9430088D19Rik protein
  • AA690119 protein
  • aiPLA2 protein
  • AOEB166 protein
  • Aop2 protein
  • Aop2-rs3 protein
  • AOPP protein
  • Brp-12 protein
  • CC26 protein
  • CP-3 protein
  • GPx protein
  • Ltw-4 protein
  • Ltw4 protein
  • Lvtw-4 protein
  • mKIAA0106 protein
  • NSGP protein
  • NSGPx protein
  • ORF06 protein
  • p29 protein
  • PHGPX protein
  • Pmp20 protein
  • Prdx5 protein
  • Prdx6 protein
  • Prdx6-rs3 protein
  • PRX protein
  • prx-6 protein
  • prx6 protein
  • PrxV protein
  • zgc:73360 protein

Protein level used designations for Peroxiredoxin 6 Proteins (PRDX6)

peroxiredoxin 6 , PLP , antioxidant enzyme B166 , liver tissue 2D-page spot 2D-0014IV , peroxiredoxin V , peroxiredoxin-5, mitochondrial , peroxisomal antioxidant enzyme , peroxisomal membrane protein 20 , prx-V , thioredoxin peroxidase PMP20 , thioredoxin reductase , 1-Cys PRX , 1-Cys peroxiredoxin , 24 kDa protein , acidic calcium-independent phospholipase A2 , antioxidant protein 2 , liver 2D page spot 40 , non-selenium glutathione peroxidase , peroxiredoxin-6 , red blood cells page spot 12 , 1-Cys Prx , anti-oxidant protein 2, related sequence 3 , peroxiredoxin 5, related sequence 3 , peroxiredoxin 6, related sequence 3 , NSGPx , aiPLA2 , thiol-specific antioxidant protein , non-selenium glutathione phospholipid hydroperoxide peroxidase , PHGPx , anti-oxidant protein 2 (non-selenium glutathione peroxidase, acidic calcium-independent phospholipase A2) , calcium-independent phospholipase A2 , ciliary body glutathione peroxidase

GENE ID SPECIES
394706 Xenopus (Silurana) tropicalis
398641 Xenopus laevis
496787 Xenopus (Silurana) tropicalis
100304983 Ictalurus punctatus
54683 Mus musculus
9588 Homo sapiens
11758 Mus musculus
94167 Rattus norvegicus
393778 Danio rerio
399434 Xenopus laevis
429062 Gallus gallus
399538 Sus scrofa
282438 Bos taurus
100173342 Pongo abelii
101842872 Mesocricetus auratus
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