Peroxisomal Biogenesis Factor 19 (PEX19) ELISA Kits

PEX19 is necessary for early peroxisomal biogenesis. Additionally we are shipping PEX19 Antibodies (78) and PEX19 Proteins (13) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human PEX19 PEX19 5824 P40855
Anti-Mouse PEX19 PEX19 19298 Q8VCI5
Anti-Rat PEX19 PEX19 289233  
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More ELISA Kits for PEX19 Interaction Partners

Human Peroxisomal Biogenesis Factor 19 (PEX19) interaction partners

  1. that newly synthesized UBXD8 (show FAF2 ELISA Kits) is post-translationally inserted into discrete ER subdomains by a mechanism requiring cytosolic PEX19 and membrane-integrated PEX3 (show PEX3 ELISA Kits), proteins hitherto exclusively implicated in peroxisome biogenesis

  2. Thus within the cell, PEX3 (show PEX3 ELISA Kits) is stabilized by PEX19 preventing PEX3 (show PEX3 ELISA Kits) aggregation.

  3. PEX19 formed a complex with the peroxisomal tail anchored protein PEX26 (show PEX26 ELISA Kits) in the cytosol and translocated it directly to peroxisomes by a TRC40 (show ASNA1 ELISA Kits)-independent class I pathway.

  4. PEX3 (show PEX3 ELISA Kits)-PEX19 interaction is crucial for de novo formation of peroxisomes in peroxisome-deficient cells.

  5. The crystal structure of the cytosolic domain of PEX3 (show PEX3 ELISA Kits) in complex with a PEX19-derived peptide. PEX3 (show PEX3 ELISA Kits) adopts a novel fold that is best described as a large helical bundle.

  6. a considerable functional diversity of the proteins encoded by two PEX19 splice variants and thereby provide first experimental evidence for specific biological functions of the different predicted domains of the PEX19 protein.

  7. PEX19 binds and stabilizes newly synthesized PMPs in the cytosol, binds to multiple PMP targeting signals (mPTSs), interacts with the hydrophobic domains of PMP targeting signals, and is essential for PMP targeting and import.

  8. Interaction of PEX3 (show PEX3 ELISA Kits) and PEX19 visualized by fluorescence resonance energy transfer (FRET).

  9. Pex19p has a role in assembly of PTS (show PTS ELISA Kits)-receptor docking complexes

  10. Results suggest that PEX3 (show PEX3 ELISA Kits) plays a selective, essential, and direct role in class I peroxisomal membrane protein (show PXMP2 ELISA Kits) import as a docking factor for PEX19.

PEX19 Antigen Profile

Antigen Summary

This gene is necessary for early peroxisomal biogenesis. It acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. These disorders have at least 14 complementation groups, with more than one phenotype being observed for some complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of Zellweger syndrome (ZWS), as well as peroxisome biogenesis disorder complementation group 14 (PBD-CG14), which is also known as PBD-CGJ. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with PEX19

  • Peroxin 19 (Pex19) antibody
  • Peroxisomal farnesylated protein (Bm1_19905) antibody
  • peroxisomal biogenesis factor 19 (PEX19) antibody
  • peroxisomal biogenesis factor 19 (Pex19) antibody
  • BEST:GH03076 antibody
  • CG5325 antibody
  • D1S2223E antibody
  • DmelPex19 antibody
  • Dmel\\CG5325 antibody
  • HK33 antibody
  • PBD12A antibody
  • Peroxin-19 antibody
  • PMP1 antibody
  • PMPI antibody
  • PxF antibody
  • PXMP1 antibody

Protein level used designations for PEX19

CG5325-PA , CG5325-PB , Pex19-PA , Pex19-PB , peroxin 19 , peroxisomal farnesylated protein , Peroxisomal farnesylated protein , 33 kDa housekeeping protein , housekeeping gene, 33kD , peroxin-19 , peroxisome biogenesis factor 19

34630 Drosophila melanogaster
6098885 Brugia malayi
5824 Homo sapiens
19298 Mus musculus
289233 Rattus norvegicus
521522 Bos taurus
100689302 Cricetulus griseus
100173241 Pongo abelii
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