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Persephin Proteins (PSPN)

The protein encoded by PSPN is a neurotrophic factor, belonging to the GDNF family. Additionally we are shipping Persephin Antibodies (45) and Persephin Kits (35) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PSPN 5623 O60542
PSPN 25525 O70301
PSPN 19197  
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Top Persephin Proteins at antibodies-online.com

Showing 10 out of 18 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated   5 μg Log in to see 10 to 12 Days
$86.96
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 2 to 3 Days
$630.00
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated   50 μg Log in to see 2 to 3 Days
$630.00
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,284.33
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated   0.005 mg Log in to see 2 to 3 Days
$178.75
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   0.005 mg Log in to see 2 to 3 Days
$178.75
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   20 μg Log in to see 7 to 9 Days
$328.21
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated   20 μg Log in to see 15 to 19 Days
$314.16
Details

PSPN Proteins by Origin and Source

Origin Expressed in Conjugate
Human

Rat (Rattus)

Mouse (Murine)

Top referenced Persephin Proteins

  1. Mouse (Murine) Persephin Protein expressed in Escherichia coli (E. coli) - ABIN2667572 : Golden, Milbrandt, Johnson: Neurturin and persephin promote the survival of embryonic basal forebrain cholinergic neurons in vitro. in Experimental neurology 2003 (PubMed)
    Show all 5 references for ABIN2667572

More Proteins for Persephin (PSPN) Interaction Partners

Human Persephin (PSPN) interaction partners

  1. Results suggested that PSPN is a possible key regulator of oral squamous cell carcinoma (OSCC) progression via PSPN-RET (show RET Proteins)-mitogen-activated protein kinase (show MAPK1 Proteins) activation and that PSPN overexpression may have diagnostic potential for OSCC.

  2. Results identify persephin, a GDNF (show GDNF Proteins) family member, as a novel ligand for GFRalpha1 (show GFRA1 Proteins)/RET (show RET Proteins) receptor complex.

  3. Persephin/GFRalpha4 is unable to recruit RET (show RET Proteins) protein into lipid rafts.

  4. The results obtained suggest the involvement of NTN (show NRTN Proteins), PSP (show MSMB Proteins), and ART in processes subserving both the organization of this cortical region during development and the functional activity and maintenance of the mature human hippocampal neurons.

Mouse (Murine) Persephin (PSPN) interaction partners

  1. Mice lacking Pspn by homologous recombination show normal development and behavior, but are hypersensitive to cerebral ischemia.

  2. TGF-beta (show TGFB1 Proteins) with neurturin (show NRTN Proteins) and persephin are required for the induction of dopaminergic neurons, whereas GDNF (show GDNF Proteins) is required for regulating and/or maintaining a differentiated neuronal phenotype

Persephin (PSPN) Protein Profile

Protein Summary

The protein encoded by this gene is a neurotrophic factor, belonging to the GDNF family. Neurotrophic factors are important for the proper development and maintenance of the nervous system. These factors promote neuronal survival and can prevent the neuronal degeneration associated with injury, toxin exposure, or neurodegenerative disease. The encoded protein has amino acid similarity to its other family members, glial cell line-derived neurotrophic factor and neurturin. This gene product promotes the survival of ventral midbrain dopaminergic neurons in culture and prevents their degeneration after 6-hydroxydopamine treatment in vivo.

Gene names and symbols associated with Persephin Proteins (PSPN)

  • persephin (PSPN)
  • persephin (Pspn)
  • persephin (LOC100356774)
  • persephin-like (LOC100518237)
  • PSP protein
  • PSPN protein

Protein level used designations for Persephin Proteins (PSPN)

persephin

GENE ID SPECIES
455638 Pan troglodytes
699480 Macaca mulatta
5623 Homo sapiens
25525 Rattus norvegicus
19197 Mus musculus
100356774 Oryctolagus cuniculus
100717500 Cavia porcellus
611734 Canis lupus familiaris
518266 Bos taurus
101109705 Ovis aries
100518237 Sus scrofa
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