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PES1 encodes a nuclear protein that contains a breast cancer associated gene 1 (BRCA1) C-terminal interaction domain. Additionally we are shipping PES1 Antibodies (41) and PES1 Proteins (5) and many more products for this protein.
These data suggest that PES1 is a marker of neuroblastoma (show ARHGEF16 ELISA Kits) outcome, that it regulates neuroblastoma (show ARHGEF16 ELISA Kits) cell proliferation, and is associated with neuroblastoma (show ARHGEF16 ELISA Kits) differentiation.
Data show that pescadillo associates with several structures that are associated with nucleogenesis, and that loss of function results in embryonic lethality due to disrupted ribosome biosynthesis.
effects of PES1 and UBF1 (show UBTF ELISA Kits) expression on the growth and differentiation of cell lines derived from 32D cells, an interleukin-3 (IL-3 (show Il3 ELISA Kits))-dependent murine myeloid cell line
Interaction with Bop1 (show BOP1 ELISA Kits) is essential for the efficient incorporation of Pes1 into nucleolar preribosomal complexes.
Mechanisms for the ability of Pes1 to transform cells, and its failure to immortalize them.
Mtap1b (show MAP1B ELISA Kits)-Light chain 1 has the potential to repress cell proliferation by modulating the nucleolar levels of Pes1
The DDX27 (show DDX27 ELISA Kits) can interact specifically with the Pes1 and Bop1 (show BOP1 ELISA Kits) but fulfils critical function(s) for proper 3' end formation of 47S rRNA independently of the PeBoW-complex.
PES1 may play important role in the progression of ovarian cancer by inversely regulating the ERalpha (show ESR1 ELISA Kits) and ERbeta (show ESR2 ELISA Kits) expression.
these results uncover a potential role of PES1 in chemoresistance by regulating DNA damage response in colorectal cancer cells.
Upstream of c-Jun (show JUN ELISA Kits), it was revealed that c-Jun (show JUN ELISA Kits) NH2-terminal kinases (JNK (show MAPK8 ELISA Kits)) is essential for controlling PES1 expression
expression of PES1 correlated positively with ERalpha (show ESR1 ELISA Kits) expression and negatively with ERbeta (show ESR2 ELISA Kits) expression and predicted good clinical outcome in breast cancer
The physical interaction between B23 (show NPM1 ELISA Kits) and PES1 implies that they may participate in ribosome biogenesis in a protein complex.
pescadillo might play a role in promoting the proliferation and carcinogenesis of human breast cancer, and thereby might be a potential target for human breast cancer treatment.
RRB1 (show GRWD1 ELISA Kits) interacts with YPH1 (yeast pescadillo homologue 1) and other members of the Yph1 complex
Pes1 and Bop1 (show BOP1 ELISA Kits) form a stable complex with a novel member, WDR12 (show WDR12 ELISA Kits) (PeBoW complex).
pes1 and ppan (show PPAN ELISA Kits) are required for Xenopus pronephros development and indicate that their function in the pronephros is independent of their role in ribosome biosynthesis
pescadillo has multiple important functions during X. laevis development; pescadillo is required for eye development and neural crest migration
This gene encodes a nuclear protein that contains a breast cancer associated gene 1 (BRCA1) C-terminal interaction domain. The encoded protein interacts with BOP1 and WDR12 to form the PeBoW complex, which plays a critical role in cell proliferation via pre-rRNA processing and 60S ribosomal subunit maturation. Expression of this gene may play an important role in breast cancer proliferation and tumorigenicity. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Pseudogenes of this gene are located on the long arm of chromosome 4 and the short arm of chromosome 9.
, pescadillo homolog 1, containing BRCT domain