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Phosphatase and Actin Regulator 4 Proteins (PHACTR4)

PHACTR4 encodes a member of the phosphatase and actin regulator (PHACTR) family. Additionally we are shipping PHACTR4 Antibodies (29) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PHACTR4 65979 Q8IZ21
PHACTR4 100169 Q501J7
Rat PHACTR4 PHACTR4 682920  
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Top PHACTR4 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details

PHACTR4 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Phosphatase and Actin Regulator 4 (PHACTR4) Interaction Partners

Human Phosphatase and Actin Regulator 4 (PHACTR4) interaction partners

  1. Data indicate that Phactr4 acts as a tumor suppressor that is deleted and mutant in several cancers.

  2. The authors show that rat Phactr1 inhibits PP1 (show PPA1 Proteins) activity in vitro, and mouse Phactr4 coimmunoprecipitates with actin and PP1 (show PPA1 Proteins) in human cells.

Mouse (Murine) Phosphatase and Actin Regulator 4 (PHACTR4) interaction partners

  1. The Phactr4 forms functional associations with intermediate filament networks in adult neural stem cells.

  2. Data discloses the central role of Phactr4 in a feedback loop, where actin monomers regulate their own number via the activation of a key regulator of actin dynamics.

  3. This study demonistrated that the mRNA expression of phactr4 was progressively increased in the injury penumbra (show TSPAN33 Proteins).

  4. hactr4 negatively regulates integrin signaling through the RHO/ROCK pathway and coordinates protein phosphatase 1 (show PPP1CB Proteins) (PP1 (show PPP1CC Proteins)) with cofilin (show CFL1 Proteins) activity to regulate cytoskeletal dynamics

  5. Phactr4 is critical for the spatially and temporally regulated transition in proliferation through differential regulation of PP1 (show PPP1CC Proteins) and the cell cycle during neurulation and eye development

PHACTR4 Protein Profile

Protein Summary

This gene encodes a member of the phosphatase and actin regulator (PHACTR) family. Other PHACTR family members have been shown to inhibit protein phosphatase 1 (PP1) activity, and the homolog of this gene in the mouse has been shown to interact with actin and PP1. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with PHACTR4

  • phosphatase and actin regulator 4b (phactr4b)
  • phosphatase and actin regulator 4 (PHACTR4)
  • phosphatase and actin regulator 4 (Tsp_08786)
  • phosphatase and actin regulator 4 (phactr4)
  • phosphatase and actin regulator 4 (Phactr4)
  • 3110001B12Rik protein
  • AI527228 protein
  • AW495572 protein
  • C330013F19Rik protein
  • mKIAA4120 protein
  • N28169 protein
  • phactr4 protein
  • zgc:63484 protein

Protein level used designations for PHACTR4

phosphatase and actin regulator 4 , phosphatase and actin regulator 4B , humdy , protein Humpty dumpty

GENE ID SPECIES
393643 Danio rerio
456684 Pan troglodytes
487333 Canis lupus familiaris
10897802 Trichinella spiralis
100145319 Xenopus (Silurana) tropicalis
100480469 Ailuropoda melanoleuca
100622686 Sus scrofa
65979 Homo sapiens
100169 Mus musculus
682920 Rattus norvegicus
425087 Gallus gallus
514644 Bos taurus
100172574 Pongo abelii
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