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Phosphate Cytidylyltransferase 2, Ethanolamine Proteins (PCYT2)

PCYT2 encodes an enzyme that catalyzes the formation of CDP-ethanolamine from CTP and phosphoethanolamine in the Kennedy pathway of phospholipid synthesis. Additionally we are shipping PCYT2 Antibodies (36) and PCYT2 Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PCYT2 5833 Q99447
PCYT2 68671 Q922E4
PCYT2 89841 O88637
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Top PCYT2 Proteins at antibodies-online.com

Showing 8 out of 9 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 10 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$3,072.67
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,120.33
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   10 μg Log in to see 3 to 4 Days
$382.86
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

PCYT2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

Rat (Rattus)

Top referenced PCYT2 Proteins

  1. Human PCYT2 Protein expressed in Escherichia coli (E. coli) - ABIN667642 : Bakovic, Fullerton, Michel: Metabolic and molecular aspects of ethanolamine phospholipid biosynthesis: the role of CTP:phosphoethanolamine cytidylyltransferase (Pcyt2). in Biochemistry and cell biology = Biochimie et biologie cellulaire 2007 (PubMed)
    Show all 2 references for ABIN667642

More Proteins for Phosphate Cytidylyltransferase 2, Ethanolamine (PCYT2) Interaction Partners

Human Phosphate Cytidylyltransferase 2, Ethanolamine (PCYT2) interaction partners

  1. differences in phosphorylation between Pcyt2 isoforms

  2. Pcyt2 expression is responsive to tumor nutritional micro-environment, up-regulated in response to metabolic stress under conditions of serum deprivation.

  3. The Pcyt2 promoter is driven by a functional CAAT box (-90/-73) and by negative (-385/-255) and positive regulatory elements (-255/-153) in the upstream regions.

  4. EGR1 (show EGR1 Proteins) is an important transcriptional stimulator of the human PCYT2 and that conditions that modify EGR1 (show EGR1 Proteins) also affect the function of ECT and consequently PE synthesis

Mouse (Murine) Phosphate Cytidylyltransferase 2, Ethanolamine (PCYT2) interaction partners

  1. we conclude that NF-Y and YY1 (show YY1 Proteins) are important for the basal transcription of Pcyt2 and that NF-Y is involved in the inhibitory effects of 25-HC on Pcyt2 transcription.

  2. The data identify Pcyt2 and membrane Phosphatidylethanolamine biogenesis as important determinants of gender-specific differences in cardiac lipids and heart function.

  3. differences in phosphorylation between Pcyt2 isoforms

  4. hypertriglyceridemia that accompanies Pcyt2 deficiency is the result of multiple metabolic adaptations

  5. data unambiguously establish that the TAG accumulation present in Pcyt2-deficient hepatocytes is a direct consequence of Pcyt2 gene deficiency and reduced functioning of the de novo Kennedy pathway

  6. single Pcyt2 allele in heterozygotes can maintain phospholipid homeostasis

  7. PE phospholipids, Pcyt2 deficiency generates compensatory changes in triglyceride and energy substrate metabolism, resulting in a progressive development of liver steatosis, hypertriglyceridemia, obesity, and insulin (show INS Proteins) resistance

  8. Regulation of the mouse CTP (show PCYT1A Proteins): phosphoethanolamine cytidylyltransferase gene Pcyt2 during myogenesis

  9. study of the importance of the CDP (show CUX1 Proteins)-ethanolamine pathway in controlling the molecular species composition of phosphatidylethanolamine via Phosphoethanolamine cytidylyltransferase knock-out

PCYT2 Protein Profile

Protein Summary

This gene encodes an enzyme that catalyzes the formation of CDP-ethanolamine from CTP and phosphoethanolamine in the Kennedy pathway of phospholipid synthesis. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with PCYT2

  • ethanolamine-phosphate cytidylyltransferase (Tc00.1047053511727.120)
  • ethanolamine-phosphate cytidylyltransferase (Tb11.01.5730)
  • ethanolamine-phosphate cytidylyltransferase (LINJ_32_0940)
  • ethanolamine-phosphate cytidylyltransferase (AaeL_AAEL005651)
  • ethanolamine-phosphate cytidylyltransferase (LmjF32.0890)
  • ethanolamine-phosphate cytidylyltransferase (EDI_013070)
  • ethanolamine-phosphate cytidylyltransferase (EDI_204270)
  • ethanolamine-phosphate cytidylyltransferase (CpipJ_CPIJ009320)
  • ethanolamine-phosphate cytidylyltransferase (Bm1_01855)
  • Ethanolamine-phosphate cytidylyltransferase (pcy2)
  • phosphate cytidylyltransferase 2, ethanolamine (PCYT2)
  • phosphate cytidylyltransferase 2, ethanolamine (Pcyt2)
  • phosphate cytidylyltransferase 2, ethanolamine (pcyt2)
  • 1110033E03Rik protein
  • ET protein

Protein level used designations for PCYT2

ethanolamine-phosphate cytidylyltransferase , putative ethanolamine-phosphate cytidylyltransferase , Ethanolamine-phosphate cytidylyltransferase , CTP:phosphoethanolamine cytidylyltransferase , phosphorylethanolamine transferase , CTP:phopshoethanolamine cytidylyltransferase

GENE ID SPECIES
3551699 Trypanosoma cruzi strain CL Brener
3665178 Trypanosoma brucei brucei strain 927/4 GUTat10.1
5071833 Leishmania infantum JPCM5
5566800 Aedes aegypti
5656202 Leishmania major strain Friedlin
5880432 Entamoeba dispar SAW760
5886247 Entamoeba dispar SAW760
6042098 Culex quinquefasciatus
6095325 Brugia malayi
100380284 Salmo salar
5833 Homo sapiens
68671 Mus musculus
444649 Xenopus laevis
510274 Bos taurus
89841 Rattus norvegicus
607608 Canis lupus familiaris
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