Phosphate Regulating Endopeptidase Homolog, X-Linked (PHEX) ELISA Kits

The protein encoded by PHEX is a transmembrane endopeptidase that belongs to the type II integral membrane zinc-dependent endopeptidase family. Additionally we are shipping PHEX Antibodies (48) and PHEX Proteins (5) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human PHEX PHEX 5251 P78562
PHEX 25512  
PHEX 18675 P70669
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Top PHEX ELISA Kits at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
General 62.5 96 Tests Log in to see 15 to 18 Days
$946.00
Details
General
62.5   96 Tests Log in to see 2 to 3 Days
$779.90
Details
Rat 4.688 ng/mL 7.8-500 ng/mL   96 Tests Log in to see 13 to 16 Days
$475.20
Details
Cow 4.688 ng/mL 7.8-500 ng/mL   96 Tests Log in to see 13 to 16 Days
$475.20
Details
Mouse 4.688 ng/mL 7.813-500 ng/mL   96 Tests Log in to see 13 to 16 Days
$475.20
Details

More ELISA Kits for PHEX Interaction Partners

Human Phosphate Regulating Endopeptidase Homolog, X-Linked (PHEX) interaction partners

  1. Expression and inactivation of osteopontin (show SPP1 ELISA Kits)-degrading PHEX enzyme in squamous cell carcinoma

  2. The novel splicing mutation IVS21+2T>G of the PHEX geneis associated with X-linked hypophosphatemia.

  3. c.931dupC and IVS14+1G>A are two novel mutations of the PHEX gene and might be the new pathogenic mutations of X-linked hypophosphatemic rickets

  4. Herpes simplex virus 1 blocks MAVS (show MAVS ELISA Kits)-Pex mediated early interferon (show IFNA ELISA Kits)-stimulated gene activation through VP16 to dampen the immediate early (show JUN ELISA Kits) antiviral innate immunity signaling from peroxisomes.

  5. Mutation in the PHEX gene is associated with type 1 diabetes.

  6. the findings of this study provide new insight into the spectrum of PHEX mutations and provide potential evidence of a critical domain in PHEX protein.

  7. This report that mutations in PHEX are the most frequent cause of hypophosphatemic rickets

  8. Downregulation of PHEX may constitute an important early component of bone loss and joint damage in leprosy

  9. PHEX c.*231A > G can masquerade as sporadic or X-linked recessive HR.

  10. A novel de novo nonsense mutation of the PHEX gene has been identified in Chinese family expanding the mutation spectrum of PHEX leading to X-linked hypophosphatemic rickets.

Mouse (Murine) Phosphate Regulating Endopeptidase Homolog, X-Linked (PHEX) interaction partners

  1. the phex mutation may create the lower set point for extracellular phosphate concentrations in a murine model of X-linked hypophosphatemia

  2. Hyp/Lrp6 (show LRP6 ELISA Kits) double mutants developed the same reduced bone mineralization,hypophosphatemia & high FGF23 (show FGF23 ELISA Kits) levels as Hyp(-) mice, showing that WNT (show WNT2 ELISA Kits) signaling does not affect the FGF23 (show FGF23 ELISA Kits)-induced phosphate wasting.

  3. demonstrates a previously unknown impact of retinol on the cell-autonomous mineralization defect of Phex-deficient osteoblasts

  4. results identify full-length OPN (show SPP1 ELISA Kits) as novel, physiologically relevant substrates for PHEX, suggesting accumulation of mineralization-inhibiting OPN (show SPP1 ELISA Kits) fragments may contribute to the mineralization defect seen in the osteomalacic bone characteristic of XLH/HYP

  5. Mutation in Phex gene predisposes BALB/c-Phex(Hyp-Duk)/Y mice to otitis media.

  6. These data suggest that Phex mutations alter the responsiveness of bone cells to extracellular phosphate concentrations and may create a lower set point for "normal" phosphate levels.

  7. PHEX and DMP1 (show DMP1 ELISA Kits) control a common pathway regulating bone mineralization and FGF23 (show FGF23 ELISA Kits) production, the latter involving activation of the FGFR (show FGFR2 ELISA Kits) signaling in osteocytes.

  8. ASARM peptides likely play a bone PHEX-dependent role in renal phosphate regulation and FGF23 (show FGF23 ELISA Kits) expression.

  9. Cooperative role of NF-{kappa}B (show NFKB1 ELISA Kits) and poly(ADP-ribose) polymerase 1 (PARP-1 (show PARP1 ELISA Kits)) in the TNF (show TNF ELISA Kits)-induced inhibition of PHEX expression in osteoblasts.

  10. OPN (show SPP1 ELISA Kits) ASARM inhibits mineralization by binding to hydroxyapatite in a phosphorylation-dependent manner and can be cleaved by PHEX.

PHEX Antigen Profile

Antigen Summary

The protein encoded by this gene is a transmembrane endopeptidase that belongs to the type II integral membrane zinc-dependent endopeptidase family. The protein is thought to be involved in bone and dentin mineralization and renal phosphate reabsorption. Mutations in this gene cause X-linked hypophosphatemic rickets.

Gene names and symbols associated with PHEX

  • phosphate regulating endopeptidase homolog, X-linked (PHEX) antibody
  • phosphate regulating endopeptidase homolog, X-linked (Phex) antibody
  • phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets) (Phex) antibody
  • Gy antibody
  • HPDR antibody
  • HPDR1 antibody
  • Hyp antibody
  • HYP1 antibody
  • LXHR antibody
  • PEX antibody
  • XLH antibody

Protein level used designations for PHEX

X-linked hypophosphatemia protein , metalloendopeptidase homolog PEX , phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets) , phosphate-regulating neutral endopeptidase , vitamin D-resistant hypophosphatemic rickets protein , phosphate regulating endopeptidase homolog, X-linked (hypophosphatemia, vitamin D resistant rickets) , Phosphate regulating neutral endopeptidase on the X chromosome (X-linked hypophosphatemia XLH) , Metalloendopeptidase homolog PEX (Phosphate regulating neutral endopeptidase) (X-linked hypophosphatemia protein) (HYP) (Vitamin D-resistant hypophosphatemic rickets protein) , X-linked phosphate regulating endopeptidase , phosphate regulating neutral endopeptidase

GENE ID SPECIES
5251 Homo sapiens
480862 Canis lupus familiaris
100154258 Sus scrofa
536029 Bos taurus
25512 Rattus norvegicus
18675 Mus musculus
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