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Phosphatidylcholine Transfer Protein Proteins (PCTP)

Catalyzes the transfer of phosphatidylcholine between membranes. Additionally we are shipping PCTP Antibodies (53) and PCTP Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PCTP 58488 Q9UKL6
PCTP 18559 P53808
PCTP 29510 P53809
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Top PCTP Proteins at antibodies-online.com

Showing 6 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,526.33
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,530.00
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

PCTP Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

Rat (Rattus)

More Proteins for Phosphatidylcholine Transfer Protein (PCTP) Interaction Partners

Human Phosphatidylcholine Transfer Protein (PCTP) interaction partners

  1. PC-TP contributes to the racial difference in PAR4 (show PAWR Proteins)-mediated platelet activation.

  2. crystal structures of human PC-TP in complex with dilinoleoyl-PtdCho or palmitoyl-linoleoyl-PtdCho reveal that a single well-ordered PtdCho molecule occupies a centrally located tunnel

  3. phosphatidylcholine transfer protein gene variants are associated with LDL-peak particle size

  4. Yeast two-hybrid screening using libraries prepared from mouse liver and embryo identified Them2 (thioesterase superfamily member 2 (show ACOT13 Proteins)) and the homeodomain transcription factor Pax3 (paired box gene 3 (show PAX3 Proteins)), respectively, as PC-TP-interacting proteins.

Mouse (Murine) Phosphatidylcholine Transfer Protein (PCTP) interaction partners

  1. Them2 (show ACOT13 Proteins) and phosphatidylcholine transfer protein regulate lipid and glucose metabolism

  2. PC-TP-THEM2 complex reduces phosphorylation and stability of IRS2 and increases stability of the TSC1-TSC2 complex

  3. Findings support a key role for Pctp in limiting mitochondrial oxidation of fatty acids and thus regulating adaptive thermogenesis in BAT (show BAAT Proteins).

  4. regulation of cholesterol homeostasis is a physiological function of PC-TP in liver, which can be overcome with a cholesterol-rich lithogenic diet

  5. In Pctp(-/-) mice, there was an accumulation of small alpha-migrating HDL (show HSD11B1 Proteins) particles. PC-TP participates in HDL (show HSD11B1 Proteins) reverse cholesterol transport.

  6. PC-TP modulates the development of atherosclerosis, in part by regulating plasma lipid concentrations

  7. NZO-derived PC-TP contained a non-synonymous point mutation that resulted in an Arg120His substitution, which was shared by the related NZB/BlNJ and NZW/LacJ mouse strains.

  8. Yeast two-hybrid screening using libraries prepared from mouse liver and embryo identified Them2 (thioesterase superfamily member 2 (show ACOT13 Proteins)) and the homeodomain transcription factor Pax3 (paired box gene 3 (show PAX3 Proteins)), respectively, as PC-TP-interacting proteins.

  9. data support a key biological role for PCTP in the regulation of energy substrate utilization, reflecting increased hepatic triglyceride production in knockout mice.

PCTP Protein Profile

Protein Summary

Catalyzes the transfer of phosphatidylcholine between membranes. Binds a single lipid molecule.

Gene names and symbols associated with PCTP

  • phosphatidylcholine transfer protein (PCTP)
  • phosphatidylcholine transfer protein (Pctp)
  • PC-TP protein
  • StarD2 protein

Protein level used designations for PCTP

START domain-containing protein 2 , StAR-related lipid transfer (START) domain containing 2 , stAR-related lipid transfer protein 2 , PC-TP , stARD2

GENE ID SPECIES
58488 Homo sapiens
18559 Mus musculus
29510 Rattus norvegicus
317656 Bos taurus
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