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Phosphatidylinositol 4-Kinase Type 2 beta Proteins (PI4K2B)

Phosphatidylinositol 4-kinases (PI4Ks) phosphorylate phosphatidylinositol to generate phosphatidylinositol 4-phosphate (PIP), an immediate precursor of several important signaling and scaffolding molecules. Additionally we are shipping Phosphatidylinositol 4-Kinase Type 2 beta Antibodies (28) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PI4K2B 55300 Q8TCG2
PI4K2B 67073 Q8CBQ5
Rat PI4K2B PI4K2B 305419 Q5XIL2
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Top Phosphatidylinositol 4-Kinase Type 2 beta Proteins at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Yeast Xenopus tropicalis His tag   1 mg Log in to see 56 to 66 Days
$3,393.50
Details
HOST_Baculovirus infected Insect Cells Human GST tag   5 μg Log in to see 10 to 12 Days
$322.08
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

PI4K2B Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for Phosphatidylinositol 4-Kinase Type 2 beta (PI4K2B) Interaction Partners

Human Phosphatidylinositol 4-Kinase Type 2 beta (PI4K2B) interaction partners

  1. Here two crystal structures are presented: the structure of human PIK42A (show PI4K2A Proteins) and the structure of PIK42B containing a nucleoside analogue.

  2. Results provide evidence that type II PtdIns 4-kinase b was indeed recruited to CD4 (show CD4 Proteins)- p56lck (show LCK Proteins) complex upon CD4 receptor cross linking, suggests a mechanism for its association and a role for it in CD4 (show CD4 Proteins)-mediated intracellular calcium release.

  3. type II PtdIns 4-kinase beta (show PI4KB Proteins) is a key component in early T cell activation signaling cascades

  4. There is no evidence to suggest that PI4K2B is contributing to bipolar disorder in this family but a role for this gene in schizophrenia has not been excluded.

  5. Type II PtdIns 4-kinase beta (show PI4KB Proteins) interacts with TCR-CD3 zeta (show CD247 Proteins) chain. The C-terminal ITAM is critical for enzyme docking on the zeta chain. The association is tyrosyl phosphorylation dependent. Mutation of Y-151 & Y-142 disrupts interaction of the 2 proteins.

  6. LB-PI4K2B-1S-specific CD4 (show CD4 Proteins)(+) T cells contributed to the antitumor response by both directly eliminating malignant cells as effector cells and stimulating CD8 (show CD8A Proteins)(+) T cell immunity as helper cells.

Mouse (Murine) Phosphatidylinositol 4-Kinase Type 2 beta (PI4K2B) interaction partners

  1. PI 4-kinase functions to negatively regulate GLUT4 (show SLC2A4 Proteins) translocation through its interaction with NCS-1 (show NCS1 Proteins).

Zebrafish Phosphatidylinositol 4-Kinase Type 2 beta (PI4K2B) interaction partners

  1. PI4-kinase type 2beta (PI4K2beta) is identified as a regulator of the trans-Golgi network (TGN (show TG Proteins))/endosomal sorting and Wnt (show WNT2 Proteins) signaling. PI4K2beta and AP-1 (show JUN Proteins) interact directly and are required for efficient sorting between endosomes and the TGN (show TG Proteins).

Phosphatidylinositol 4-Kinase Type 2 beta (PI4K2B) Protein Profile

Protein Summary

Phosphatidylinositol 4-kinases (PI4Ks) phosphorylate phosphatidylinositol to generate phosphatidylinositol 4-phosphate (PIP), an immediate precursor of several important signaling and scaffolding molecules. PIP itself may also have direct functional and structural roles. PI4K2B is a primarily cytosolic PI4K that is recruited to membranes, where it stimulates phosphatidylinositol 4,5-bisphosphate synthesis (Wei et al., 2002

Gene names and symbols associated with PI4K2B

  • phosphatidylinositol 4-kinase II beta (Pi4k2b)
  • phosphatidylinositol 4-kinase type 2 beta (pi4k2b)
  • phosphatidylinositol 4-kinase type 2 beta (PI4K2B)
  • phosphatidylinositol 4-kinase type 2 beta (LOC100345479)
  • phosphatidylinositol 4-kinase type 2 beta (Pi4k2b)
  • 2610042N09Rik protein
  • 4933409G22Rik protein
  • GB16449 protein
  • PI4KIIB protein
  • PIK42B protein
  • zgc:158305 protein

Protein level used designations for PI4K2B

phosphatidylinositol 4-kinase type 2-beta , phosphatidylinositol 4-kinase type II-beta , phosphatidylinositol 4-kinase type 2 beta , phosphatidylinositol 4-kinase type 2-beta-like , PI4KII-BETA , phosphatidylinositol 4-kinase type-II beta , type II phosphatidylinositol 4-kinase beta , PI4KII-beta , phosphatidylinositol 4-kinase II beta , pi4kII beta

GENE ID SPECIES
725812 Apis mellifera
446885 Xenopus laevis
521790 Bos taurus
549707 Xenopus (Silurana) tropicalis
100345479 Oryctolagus cuniculus
100408979 Callithrix jacchus
100591265 Nomascus leucogenys
100623115 Sus scrofa
55300 Homo sapiens
67073 Mus musculus
305419 Rattus norvegicus
422807 Gallus gallus
564750 Danio rerio
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