You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Phosphatidylinositol Glycan Anchor Biosynthesis, Class A (PIGA) Antibodies

PIGA encodes a protein required for synthesis of N-acetylglucosaminyl phosphatidylinositol (GlcNAc-PI), the first intermediate in the biosynthetic pathway of GPI anchor. Additionally we are shipping PIGA Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PIGA 5277 P37287
PIGA 18700 Q64323
PIGA 363464  
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top anti-PIGA Antibodies at antibodies-online.com

Showing 10 out of 50 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Immunohistochemistry analysis in human brain tissue using PIGA  Antibody  (C-term), followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of PIGA antibody for IHC. Clinical relevance has not been evaluated. Western blot analysis in MDA-MB435 cell line lysates (35ug/lane) using PIGA  Antibody . This demonstrates the PIGA antibody detected the PIGA protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-PIGA Antibody Titration: 0.2-1 ug/mlPositive Control: OVCAR-3 cell lysate WB Suggested Anti-PIGA  Antibody Titration: 0.2-1 µg/mL  Positive Control: OVCAR-3 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), WB PIGA Antibody (C-term)  western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the PIGA antibody detected the PIGA protein (arrow). PIGA Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PIGA Antibody (C-term) for immunohistochemistry.  Clinical relevance has not been evaluated. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB WB Image Sample (30 ug of whole cell lysate) A: NIH-3T3 10% SDS PAGE antibody diluted at 1:1000 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated IHC, WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit APC IHC, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Alexa Fluor 350 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 488 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details

PIGA Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , , ,


, , , , , , , , , , , , , ,
Mouse (Murine) ,


, , , , , , , , , , ,
Rat (Rattus) ,


, , , , , , , , , , ,

Top referenced anti-PIGA Antibodies

  1. Human Polyclonal PIGA Primary Antibody for EIA, IHC (p) - ABIN954134 : Borowitz, Craig, Digiuseppe, Illingworth, Rosse, Sutherland, Wittwer, Richards: Guidelines for the diagnosis and monitoring of paroxysmal nocturnal hemoglobinuria and related disorders by flow cytometry. in Cytometry. Part B, Clinical cytometry 2010 (PubMed)
    Show all 3 references for ABIN954134

  2. Cow (Bovine) Polyclonal PIGA Primary Antibody for WB - ABIN2782189 : Traulsen, Pacheco, Dingli: On the origin of multiple mutant clones in paroxysmal nocturnal hemoglobinuria. in Stem cells (Dayton, Ohio) 2007 (PubMed)

More Antibodies against PIGA Interaction Partners

Human Phosphatidylinositol Glycan Anchor Biosynthesis, Class A (PIGA) interaction partners

  1. A recurrent germline mutation in the PIGA gene causes Simpson-Golabi-Behmel syndrome type 2.

  2. This case reports on a new missense PIGA germline mutation in a Chinese male infant presenting with developmental arrest and multisystemic disorders.

  3. the PIGA mutation in this family likely causes a reduction in GPI (show GNPDA1 Antibodies) anchor protein (show CELSR3 Antibodies) cell surface expression in various cell types, resulting in the observed pleiotropic phenotype involving central nervous system, skin, and iron metabolism.

  4. Our data strongly suggest that the early frameshift mutation in PIGA produces a truncated hypomorph, which is sufficient to rescue the lethality in males but not the MCAHS2-like phenotype.

  5. The results of this study confirmed that PIGA mutations are one genetic cause of early-onset epileptic encephalopathies, suggesting that GPI (show GNPDA1 Antibodies)-anchor deficiencies may be an underlying cause of EOEE.

  6. The small population of PIG-A mutant cells in myelodysplastic syndromes do not arise from multipotent hematopoietic stem cells.

  7. An X chromosome exome next-generation sequencing screen identified a single nonsense PIGA mutation.

  8. loss of PIG-A or a combination of genes within the 0.5 Mb commonly deleted region leads to a phenotype capable of avoiding immune surveillance, but is not inherently malignant.

  9. the PIG-A mutations in paroxysmal nocturnal hemoglobinuria patients

  10. Molecular testing for mutations in the PIG-A gene can serve as a confirmation test of paroxysmal nocturnal hemoglobinuria.

Mouse (Murine) Phosphatidylinositol Glycan Anchor Biosynthesis, Class A (PIGA) interaction partners

  1. Single cell gel electrophoresis (SCGE (show SGCE Antibodies)) and Pig-a mutation assay in vivo-tools for genotoxicity testing from a regulatory perspective: a study of benzo[a]pyrene in Ogg1 (show OGG1 Antibodies)(-/-) mice.

  2. Reduced IgE/antigen-mediated passive cutaneous anaphylaxis is detected in mice with Piga-deficient mast cells.

  3. Deletion of the Pig-a gene in hematopoietic cells does not cause frank marrow failure but leads to the appearance of clonally-restricted, inactive yet functionally competent CD8 (show CD8A Antibodies) T cells.

  4. Piga gene mutation does not alter susceptibility to cell death in thymocytes, granulocytes, and hematopoietic progenitor cells.

  5. Pig-a-knockout females are infertile, and eggs recovered from the females after mating are unfertilized.

  6. processing profilaggrin (show FLG Antibodies) to its monomeric form was impaired in Pig-a null mouse epidermis

  7. Piga expression is required to properly orient hair cells in the inner ear, a process regulated by the planar cell polarity pathway.

PIGA Antigen Profile

Protein Summary

This gene encodes a protein required for synthesis of N-acetylglucosaminyl phosphatidylinositol (GlcNAc-PI), the first intermediate in the biosynthetic pathway of GPI anchor. The GPI anchor is a glycolipid found on many blood cells and which serves to anchor proteins to the cell surface. Paroxysmal nocturnal hemoglobinuria, an acquired hematologic disorder, has been shown to result from mutations in this gene. Alternate splice variants have been characterized. A related pseudogene is located on chromosome 12.

Gene names and symbols associated with PIGA

  • phosphatidylinositol glycan anchor biosynthesis, class A (PIGA) antibody
  • phosphatidylinositol glycan anchor biosynthesis, class A (Piga) antibody
  • AI194334 antibody
  • GPI3 antibody
  • MCAHS2 antibody
  • Pig-a antibody

Protein level used designations for PIGA

N-acetylglucosaminyl-phosphatidylinositol biosynthetic protein , phosphatidylinositol glycan anchor biosynthesis, class A (paroxysmal nocturnal hemoglobinuria) , phosphatidylinositol glycan, class A (paroxysmal nocturnal hemoglobinuria) , GLCNAC-PI synthesis protein , GPI anchor biosynthesis , class A GlcNAc-inositol phospholipid assembly protein , phosphatidylinositol N-acetylglucosaminyltransferase subunit A , phosphatidylinositol-glycan biosynthesis, class A protein , glcNAc-PI synthesis protein , phosphatidylinositol glycan, class A , phosphatidylinositol-glycan biosynthesis class A protein , phosphatidylinositolglycan class A

GENE ID SPECIES
418624 Gallus gallus
100055827 Equus caballus
100156880 Sus scrofa
5277 Homo sapiens
491748 Canis lupus familiaris
100139601 Bos taurus
18700 Mus musculus
363464 Rattus norvegicus
Selected quality suppliers for anti-PIGA (PIGA) Antibodies
Did you look for something else?