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Phosphatidylinositol Glycan Anchor Biosynthesis, Class V (PIGV) ELISA Kits

PIGV encodes a mannosyltransferase enzyme involved in the biosynthesis of glycosylphosphatidylinositol (GPI). Additionally we are shipping PIGV Antibodies (23) and PIGV Proteins (3) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human PIGV PIGV 55650 Q9NUD9
Anti-Mouse PIGV PIGV 230801 Q7TPN3
Anti-Rat PIGV PIGV 366478 Q5KR61
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More ELISA Kits for PIGV Interaction Partners

Human Phosphatidylinositol Glycan Anchor Biosynthesis, Class V (PIGV) interaction partners

  1. Data indicate that mannosyltransferases PIGV mutations are the major cause of hyperphosphatasia-mental retardation syndrome (HPMRS) which displays a broad clinical variability regarding associated malformations and growth patterns.

  2. PIGV is the rate-limiting enzyme in GPI (show GNPDA1 ELISA Kits) biosynthesis under limited dolicholphosphate mannose availability.

  3. Hyperphosphatasia resulted from secretion of ALP (show ALP ELISA Kits), a GPI (show GNPDA1 ELISA Kits)-anchored protein normally expressed on the cell surface, into serum due to PIGV deficiency.

  4. novel compound heterozygous mutations in the PIGV gene c.467G>A and c.1022C>A and a homozygous mutation c.1022C>A in hyperphosphatasia-mental retardation syndrome

  5. PIGV mutations are associated with hyperphosphatasia mental retardation syndrome.

  6. PIG-V is the second mannosyltransferase in GPI anchor biosynthesis (show PIGA ELISA Kits).

PIGV Antigen Profile

Antigen Summary

This gene encodes a mannosyltransferase enzyme involved in the biosynthesis of glycosylphosphatidylinositol (GPI). GPI is a complex glycolipid that functions as a membrane anchor for many proteins and plays a role in multiple cellular processes including protein sorting and signal transduction. The encoded protein is localized to the endoplasmic reticulum and transfers the second mannose to the GPI backbone. Mutations in this gene are associated with hyperphosphatasia mental retardation syndrome. Alternatively spliced transcript variants have been observed for this gene.

Gene names and symbols associated with PIGV

  • phosphatidylinositol glycan anchor biosynthesis, class V (PIGV) antibody
  • phosphatidylinositol glycan anchor biosynthesis, class V (Pigv) antibody
  • B330013B03 antibody
  • D430024F16Rik antibody
  • GPI-MT-II antibody
  • HPMRS1 antibody
  • PIG-V antibody
  • RGD1309526 antibody

Protein level used designations for PIGV

GPI mannosyltransferase 2 , GPI mannosyltransferase II , Ybr004c homolog , dol-P-Man dependent GPI mannosyltransferase , GPI-MT-II , PIG-V , phosphatidylinositol glycan class V , phosphatidylinositol glycan, class V , phosphatidylinositol-glycan biosynthesis class V protein

GENE ID SPECIES
55650 Homo sapiens
478172 Canis lupus familiaris
519213 Bos taurus
230801 Mus musculus
366478 Rattus norvegicus
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