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Phosphatidylinositol Glycan Anchor Biosynthesis, Class V Proteins (PIGV)

PIGV encodes a mannosyltransferase enzyme involved in the biosynthesis of glycosylphosphatidylinositol (GPI). Additionally we are shipping PIGV Antibodies (25) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PIGV 55650 Q9NUD9
PIGV 230801 Q7TPN3
Rat PIGV PIGV 366478 Q5KR61
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Top PIGV Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details

PIGV Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Phosphatidylinositol Glycan Anchor Biosynthesis, Class V (PIGV) Interaction Partners

Human Phosphatidylinositol Glycan Anchor Biosynthesis, Class V (PIGV) interaction partners

  1. Data indicate that mannosyltransferases PIGV mutations are the major cause of hyperphosphatasia-mental retardation syndrome (HPMRS) which displays a broad clinical variability regarding associated malformations and growth patterns.

  2. PIGV is the rate-limiting enzyme in GPI (show GNPDA1 Proteins) biosynthesis under limited dolicholphosphate mannose availability.

  3. Hyperphosphatasia resulted from secretion of ALP (show ALP Proteins), a GPI (show GNPDA1 Proteins)-anchored protein normally expressed on the cell surface, into serum due to PIGV deficiency.

  4. novel compound heterozygous mutations in the PIGV gene c.467G>A and c.1022C>A and a homozygous mutation c.1022C>A in hyperphosphatasia-mental retardation syndrome

  5. PIGV mutations are associated with hyperphosphatasia mental retardation syndrome.

  6. PIG-V is the second mannosyltransferase in GPI anchor biosynthesis (show PIGA Proteins).

PIGV Protein Profile

Protein Summary

This gene encodes a mannosyltransferase enzyme involved in the biosynthesis of glycosylphosphatidylinositol (GPI). GPI is a complex glycolipid that functions as a membrane anchor for many proteins and plays a role in multiple cellular processes including protein sorting and signal transduction. The encoded protein is localized to the endoplasmic reticulum and transfers the second mannose to the GPI backbone. Mutations in this gene are associated with hyperphosphatasia mental retardation syndrome. Alternatively spliced transcript variants have been observed for this gene.

Gene names and symbols associated with PIGV

  • phosphatidylinositol glycan anchor biosynthesis, class V (PIGV)
  • phosphatidylinositol glycan anchor biosynthesis, class V (Pigv)
  • B330013B03 protein
  • D430024F16Rik protein
  • GPI-MT-II protein
  • HPMRS1 protein
  • PIG-V protein
  • RGD1309526 protein

Protein level used designations for PIGV

GPI mannosyltransferase 2 , GPI mannosyltransferase II , Ybr004c homolog , dol-P-Man dependent GPI mannosyltransferase , GPI-MT-II , PIG-V , phosphatidylinositol glycan class V , phosphatidylinositol glycan, class V , phosphatidylinositol-glycan biosynthesis class V protein

GENE ID SPECIES
55650 Homo sapiens
478172 Canis lupus familiaris
519213 Bos taurus
230801 Mus musculus
366478 Rattus norvegicus
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