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PIGL encodes an enzyme that catalyzes the second step of glycosylphosphatidylinositol (GPI) biosynthesis, which is the de-N-acetylation of N-acetylglucosaminylphosphatidylinositol (GlcNAc-PI). Additionally we are shipping PIGL Proteins (9) and PIGL Kits (1) and many more products for this protein.
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Human Polyclonal PIGL Primary Antibody for EIA, WB - ABIN954136
Pottekat, Menon: Subcellular localization and targeting of N-acetylglucosaminyl phosphatidylinositol de-N-acetylase, the second enzyme in the glycosylphosphatidylinositol biosynthetic pathway. in The Journal of biological chemistry 2004
Show all 5 references for ABIN954136
Whole-exome sequencing on five previously reported CHIME cases identified PIGL (N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase) as required for glycosylphosphatidylinositol anchor formation.
This gene encodes an enzyme that catalyzes the second step of glycosylphosphatidylinositol (GPI) biosynthesis, which is the de-N-acetylation of N-acetylglucosaminylphosphatidylinositol (GlcNAc-PI). Study of a similar rat enzyme suggests that this protein localizes to the endoplasmic reticulum.
, N-acetylglucosaminylphosphatidylinositol deacetylase
, phosphatidylinositol glycan, class L
, phosphatidylinositol-glycan biosynthesis class L protein
, ortholog of human and rat phosphatidylinositol glycan class L PIGL