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Phosphodiesterase 12 Proteins (PDE12)

Enzyme that cleaves 2',5'-phosphodiester bond linking adenosines of the 5'-triphosphorylated oligoadenylates, triphosphorylated oligoadenylates referred as 2-5A modulates the 2-5A system. Additionally we are shipping PDE12 Antibodies (31) and PDE12 Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PDE12 201626 Q6L8Q7
PDE12 211948 Q3TIU4
PDE12 306231  
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Top PDE12 Proteins at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Baculovirus infected Insect Cells Human GST tag   50 μg Log in to see 10 to 12 Days
$570.24
Details
HOST_Escherichia coli (E. coli) Rat Un-conjugated   5 applications Log in to see 1 to 2 Days
$312.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

PDE12 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

Rat (Rattus)

More Proteins for Phosphodiesterase 12 (PDE12) Interaction Partners

Human Phosphodiesterase 12 (PDE12) interaction partners

  1. PDE12 is a negative regulator of the antiviral innate immune response.

  2. 2'-phosphodiesterase is a mitochondrial protein (show COX6B2 Proteins) that specifically removes poly(A) extensions from mitochondrial mRNAs both in vitro and in mitochondria of cultured cells.

  3. 2'-PDE locates to the mitochondrial matrix of human cells, and comprise an active 3'-5' exoribonuclease exhibiting a preference for oligo-adenosine RNA like canonical cytoplasmic deadenylases.

  4. crystals of phosphodiesterase 12 belonged to space group P3(1)21 or P3(2)21, with unit-cell parameters a = b = 111.3, c = 192.4 A, and diffracted to 2.5 A resolution.

PDE12 Protein Profile

Protein Summary

Enzyme that cleaves 2',5'-phosphodiester bond linking adenosines of the 5'-triphosphorylated oligoadenylates, triphosphorylated oligoadenylates referred as 2-5A modulates the 2-5A system. This enzyme degraded triphosphorylated 2-5A to produce AMP and ATP. Also cleaves 3',5'-phosphodiester bond of oligoadenylates. Plays a role as a negative regulator of the The 2-5A system that is one of the major pathways for antiviral and antitumor functions induced by interferons (IFNs) (By similarity).

Gene names and symbols associated with Phosphodiesterase 12 Proteins (PDE12)

  • phosphodiesterase 12 (pde12)
  • phosphodiesterase 12 (PDE12)
  • phosphodiesterase 12 (Pde12)
  • 2'-PDE protein
  • E430028B21Rik protein
  • LRRGT00074 protein
  • RGD1310975 protein

Protein level used designations for Phosphodiesterase 12 Proteins (PDE12)

phosphodiesterase 12 , 2'-phosphodiesterase , 2',5'-phosphodiesterase 12-like , 2',5'-phosphodiesterase 12 , 2-PDE , 2'-PDE

GENE ID SPECIES
443670 Xenopus laevis
461027 Pan troglodytes
703552 Macaca mulatta
734133 Xenopus (Silurana) tropicalis
100058532 Equus caballus
100403371 Callithrix jacchus
100439178 Pongo abelii
100600767 Nomascus leucogenys
201626 Homo sapiens
484714 Canis lupus familiaris
538860 Bos taurus
211948 Mus musculus
306231 Rattus norvegicus
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