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Phosphodiesterase 4B Proteins (PDE4B)

contains four isoforms expressed from the same gene\; isoform Pde4b4 has cAMP specific phosphdiesterase activity and is inhibited by rolipram [RGD, Feb 2006].. Additionally we are shipping Phosphodiesterase 4B Antibodies (22) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PDE4B 18578  
PDE4B 24626 P14646
PDE4B    
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Top Phosphodiesterase 4B Proteins at antibodies-online.com

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Catalog No. Origin Source Conjugate Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human Un-conjugated 5 applications Log in to see 1 to 2 Days
$344.14
Details

PDE4B Proteins by Origin and Source

Origin Expressed in
Mouse (Murine)
Rat (Rattus)
Human

More Proteins for Phosphodiesterase 4B (PDE4B) Interaction Partners

Mouse (Murine) Phosphodiesterase 4B (PDE4B) interaction partners

  1. PDE4B phosphorylated by AMPK (show PRKAA1 Proteins) at Ser304 is important for activation.

  2. Lymphomas developing in a Pde4b-null background display significantly lower microvessel density in association with lower VEGF (show VEGFA Proteins) levels and PI3K/AKT (show AKT1 Proteins) activity.

  3. Genetic variations in DISC1 influence formation of biochemical complex with PDE4 and GSK-3 and strengthen the possibility of synergistic interactions between these proteins.

  4. PDE4B-deficient mice display impaired reversal learning in the Morris water maze compared to wild-type littermates.

  5. Results identify PDE4B in the CaV1.2 (show CACNA1C Proteins) complex as a critical regulator of ICa during beta-AR stimulation and suggest that distinct PDE4 (show PDE4A Proteins) subtypes are important for normal regulation of calcium-induced calcium release in cardiomyocytes.

  6. Findings demonstrate that PDE4D (show PDE4D Proteins) and PDE4B have specialized functions in mouse embryonic fibroblasts with PDE4B controlling cAMP in a discrete subdomain near the plasma membrane.

  7. induction is esssential for LPS (show TLR4 Proteins)-activated tnf-alpha (show TNF Proteins) responses

  8. PDE4B mediates the antipsychotic effects of rolipram in conditioned avoidance responding; the PDE4B-regulated cyclic adenosine monophosphate signaling pathway may play a role in the pathophysiology and pharmacotherapy of psychosis

  9. the PDE4B subfamily is involved in signaling pathways that contribute to anxiogenic-like effects on behavior.

  10. Altered DISC1 (show DISC1 Proteins)-PDE4B interaction may thus underlie the symptoms of some cases of schizophrenia and depression.(Review)

Phosphodiesterase 4B (PDE4B) Protein Profile

Protein Summary

contains four isoforms expressed from the same gene\; isoform Pde4b4 has cAMP specific phosphdiesterase activity and is inhibited by rolipram

Gene names and symbols associated with Phosphodiesterase 4B Proteins (PDE4B)

  • phosphodiesterase 4B, cAMP-specific a (pde4ba)
  • phosphodiesterase 4B, cAMP specific (Pde4b)
  • Dpde4 protein
  • dunce protein
  • fj87g04 protein
  • PDE4/IVb protein
  • pde4b protein
  • Pde4B1 protein
  • Pde4B2 protein
  • Pde4B3 protein
  • Pde4B4 protein
  • R74983 protein
  • wu:fj87g04 protein

Protein level used designations for Phosphodiesterase 4B Proteins (PDE4B)

phosphodiesterase 4B, cAMP-specific a , phosphodiesterase 4B, cAMP-specific (phosphodiesterase E4 dunce homolog, Drosophila) , phosphodiesterase 4B , 3',5'-cyclic AMP phosphodiesterase , DPDE4 , Phosphodiesterase 4B cAMP-specific (dunce , Phosphodiesterase 4B, cAMP-specific (dunce , cAMP-specific 3',5'-cyclic phosphodiesterase 4B

GENE ID SPECIES
337624 Danio rerio
18578 Mus musculus
24626 Rattus norvegicus
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