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anti-Phosphogluconate Dehydrogenase (PGD) Antibodies

6-phosphogluconate dehydrogenase is the second dehydrogenase in the pentose phosphate shunt. Additionally we are shipping PGD Proteins (18) and PGD Kits (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PGD 236539 Q61753
PGD 5226 P52209
PGD 362660  
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Top anti-PGD Antibodies at antibodies-online.com

Showing 10 out of 73 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-PGD AntibodyTitration: 1.0 µg/mL  Positive Control: Jurkat Whole Cell  PGD is supported by BioGPS gene expression data to be expressed in Jurkat 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB PGD Antibody (Center) (ABIN651639) western blot analysis in 293,MCF-7 cell line lysates (35 µg/lane). This demonstrates the PGD antibody detected PGD protein (arrow). PGD Antibody (Center) (ABIN651639) western blot analysis in mouse spleen tissue lysates (35 µg/lane). This demonstrates the PGD antibody detected PGD protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated ICC, IF, IHC (p), WB WB Image PGD antibody [N1N3] detects PGD protein by western blot analysis. Mouse tissue extracts (50 μg) was separated by 10% SDS-PAGE, and the membrane was blotted with PGD antibody [N1N3] , diluted at 1:1000. IHC-P Image PGD antibody [N1N3] detects PGD protein at cytoplasm on A549 xenograft by immunohistochemical analysis. Sample: Paraffin-embedded A549 xenograft. PGD antibody [N1N3] , dilution: 1:500. 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Rabbit Un-conjugated ICC, WB   100 μL Log in to see 8 to 10 Days
$507.83
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 14 Days
$201.19
Details
Human Rabbit Un-conjugated ELISA, WB   100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Mouse Un-conjugated WB Western Blot analysis of PGD expression in transfected 293T cell line by PGD MaxPab polyclonal antibody.Lane 1: PGD transfected lysate(53.13 KDa).Lane 2: Non-transfected lysate. 50 μL Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated IF, WB 100 μL Log in to see 6 to 11 Days
$485.71
Details
Human Rabbit Un-conjugated ELISA   200 μL Log in to see 8 to 10 Days
$713.17
Details

PGD Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine)


Human ,
,
,
, , , , ,
Rat (Rattus)


More Antibodies against PGD Interaction Partners

Mouse (Murine) Phosphogluconate Dehydrogenase (PGD) interaction partners

  1. These results indicate that the PHGDH (show PHGDH Antibodies) gene expression, dictated by IL-2R signaling, is a crucial event for DNA synthesis during S phase of activated T cells.

  2. Using transgenic mice expressing enhanced GFP under the Srr (show SRR Antibodies) promoter and mice with targeted deletion of Srr (show SRR Antibodies) or 3-Phosphoglycerate dehydrogenase (show PHGDH Antibodies), we demonstrate predominantly neuronal sources of d-serine dependent on astrocytic supply of l-serine.

  3. Elevated levels of 4E-BP1 (show EIF4EBP1 Antibodies) may be involved in a mechanism to arrest brain development in Phgdh (show PHGDH Antibodies) knock out embryos.

  4. Glycolytic cancer cells lacking 6-phosphogluconate dehydrogenase metabolize glucose to induce senescence

  5. Phgdh (show PHGDH Antibodies) deletion reveals a pivotal role for L-serine biosynthesis in controlling the level of brain D-serine, an N-methyl-D-aspartate receptor (show GRIN1 Antibodies) co-agonist

  6. Data suggest expression of Phgdh (show PHGDH Antibodies) in endometrium is regulated by Hoxa10 (show HOXA10 Antibodies).

  7. Taken together, these data suggest that ADD1/SREBP1c (show SREBF1 Antibodies) is a key transcription factor for 6PGDH gene expression and would coordinate glucose metabolism and lipogenesis for energy homeostasis.

  8. the Phgdh (show PHGDH Antibodies)-dependent phosphorylated pathway is essential for normal embryonic development, especially for brain morphogenesis

  9. the presence of cis (show CISH Antibodies)-acting elements confer the cell type specificity of Phgdh (show PHGDH Antibodies) transcription in the distal promoter region.

  10. The mouse Phgdh (show PHGDH Antibodies) gene spans approximately 27 kilobases in length and comprises 12 exons with 11 intervening introns and is mapped to chromosome 3, region F2-F3 by FISH.

Human Phosphogluconate Dehydrogenase (PGD) interaction partners

  1. Studies indicate link between the 6-phosphogluconate dehydrogenase, oxidative pentose phosphate pathway (PPP) and lipogenesis through Ru-5-P-dependent inhibition of serine/threonine protein kinase LKB1 (show STK11 Antibodies)-AMPK (show PRKAA1 Antibodies) signalling.

  2. copy number gain of the PGD gene was consistently identified in cervical cancers but not in the normal tissues

  3. Results show that 6PGD activity is upregulated with increased lysine acetylation in primary leukemia cells from human patients, providing mechanistic insights into 6PGD upregulation in cancer cells.

  4. Expression of 6PGD positively correlates with advancing stage of lung carcinoma. Knockdown of 6PGD by shRNA potently inhibits c-Met tyrosine phosphorylation.

  5. Glycolytic cancer cells lacking 6-phosphogluconate dehydrogenase metabolize glucose to induce senescence

  6. Data suggest that the affinity of Nox2 (show CYBB Antibodies) for NADPH (show NQO1 Antibodies) is increased in the presence of 6PGDH on cell stimulation.

  7. Hsa (show CD24 Antibodies)-miR (show MLXIP Antibodies)-132 and -212 were negatively correlated with PGD in the prefrontal cortex of individuals affected with schizophrenia and bipolar disorders.

PGD Antigen Profile

Protein Summary

6-phosphogluconate dehydrogenase is the second dehydrogenase in the pentose phosphate shunt. Deficiency of this enzyme is generally asymptomatic, and the inheritance of this disorder is autosomal dominant. Hemolysis results from combined deficiency of 6-phosphogluconate dehydrogenase and 6-phosphogluconolactonase suggesting a synergism of the two enzymopathies.

Gene names and symbols associated with PGD

  • Phosphogluconate dehydrogenase (Pgd) antibody
  • phosphogluconate dehydrogenase (pgd) antibody
  • phosphogluconate hydrogenase (pgd) antibody
  • phosphogluconate dehydrogenase (PGD) antibody
  • 6-phosphogluconate dehydrogenase, decarboxylating (GND1a|GND1b) antibody
  • 6-phosphogluconate dehydrogenase, decarboxylating (Thal_1580) antibody
  • 6-phosphogluconate dehydrogenase, decarboxylating (GY4MC1_3101) antibody
  • 6-phosphogluconate dehydrogenase, decarboxylating (Odosp_2189) antibody
  • 6-phosphogluconate dehydrogenase, decarboxylating (Marky_1024) antibody
  • 6-phosphogluconate dehydrogenase, decarboxylating (gnd) antibody
  • 3-phosphoglycerate dehydrogenase (Phgdh) antibody
  • 6-phosphogluconate dehydrogenase, decarboxylating-like (LOC101451876) antibody
  • phosphogluconate dehydrogenase (Pgd) antibody
  • 3-PGDH antibody
  • 3PGDH antibody
  • 6-pgd antibody
  • 6-PGDH antibody
  • 6Pgd antibody
  • 6pgdh antibody
  • 0610042A05Rik antibody
  • 4930479N23 antibody
  • A7 antibody
  • A10 antibody
  • AU019875 antibody
  • C78335 antibody
  • Cc2-27 antibody
  • CG3724 antibody
  • Dmel\\CG3724 antibody
  • EG:87B1.4 antibody
  • fi03d03 antibody
  • GND1b antibody
  • l(1)2Dc antibody
  • l(1)2De antibody
  • l(1)A7 antibody
  • l(1)G0385 antibody
  • l(1)N1 antibody
  • l(1)N3[90] antibody
  • l(1)Pgd antibody
  • l(1)Pgd-A antibody
  • l35 antibody
  • N1 antibody
  • Pdg antibody
  • PGAD antibody
  • Pgd antibody
  • PGDH antibody
  • SERA antibody
  • wu:fi03d03 antibody
  • zgc:55585 antibody
  • zgc:111848 antibody

Protein level used designations for PGD

6-phosphogluconate , 6-phosphogluconate dehydrogenase , CG3724-PA , CG3724-PB , NADP-6 phosphogluconate dehydrogenase , Pgd-PA , Pgd-PB , dehydrogenase , phosphogluconate dehydrogenase , 6-phosphogluconate dehydrogenase, decarboxylating , 3-phosphoglycerate dehyrogenase , D-3-phosphoglycerate dehydrogenase , 6-phosphogluconate dehydrogenase (decarboxylating)

GENE ID SPECIES
31185 Drosophila melanogaster
398848 Xenopus laevis
406762 Danio rerio
419450 Gallus gallus
514939 Bos taurus
5722476 Chlamydomonas reinhardtii
8815110 Thermocrinis albus DSM 14484
9929981 Geobacillus sp. Y4.1MC1
10253936 Odoribacter splanchnicus DSM 220712
10433922 Marinithermus hydrothermalis DSM 14884
10448388 Chlamydophila pecorum E58
100534626 Taeniopygia guttata
100598383 Nomascus leucogenys
236539 Mus musculus
101451876 Ceratitis capitata
5226 Homo sapiens
110208 Mus musculus
362660 Rattus norvegicus
397546 Sus scrofa
443541 Ovis aries
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