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The protein encoded by PLTP is one of at least two lipid transfer proteins found in human plasma. Additionally we are shipping PLTP Kits (30) and PLTP Proteins (10) and many more products for this protein.
Showing 10 out of 88 products:
Human Polyclonal PLTP Primary Antibody for ICC, IF - ABIN152885
Valenta, Ogier, Bradshaw, Black, Bonnet, Lagrost, Curtiss, Desrumaux: Atheroprotective potential of macrophage-derived phospholipid transfer protein in low-density lipoprotein receptor-deficient mice is overcome by apolipoprotein AI overexpression. in Arteriosclerosis, thrombosis, and vascular biology 2006
Show all 7 references for ABIN152885
Human Monoclonal PLTP Primary Antibody for WB - ABIN395590
Kuerban, Shibata, Komatsu, Ohnuma, Arai: Genetic association between PLTP gene polymorphisms and Alzheimer's disease in a Japanese population. in Dementia and geriatric cognitive disorders 2010
Show all 5 references for ABIN395590
Human Monoclonal PLTP Primary Antibody for IHC (p), ELISA - ABIN562287
Derbali, Bossé, Côté, Pibarot, Audet, Pépin, Arsenault, Couture, Després, Mathieu: Increased biglycan in aortic valve stenosis leads to the overexpression of phospholipid transfer protein via Toll-like receptor 2. in The American journal of pathology 2010
Human Polyclonal PLTP Primary Antibody for FACS, IHC (p) - ABIN391914
Albers, Wolfbauer, Cheung, Day, Ching, Lok, Tu: Functional expression of human and mouse plasma phospholipid transfer protein: effect of recombinant and plasma PLTP on HDL subspecies. in Biochimica et biophysica acta 1995
identification and characterization of CaM (show CALM Antibodies)-binding domain of non-specific lipid transfer proteins
association of PON-1 (show PON1 Antibodies) activity with PLTP activity was lost in analysis which included large HDL (show HSD11B1 Antibodies) particles
a novel association between PLTPa and PON1 (show PON1 Antibodies) activity
The domain of apolipoprotein E4 required for PLTP activation resides within its amino-terminal 1-185 region.
Elevated baseline plasma levels of PLTP are associated with an increased risk of long-term all-cause mortality in patients with diabetes and known or suspected coronary disease.
This review summarizes the recent progresses made in the PLTP research field and focuses on the complexity of the implication of PLTP in obesity, insulin (show INS Antibodies) resistance and type 2 diabetes mellitus. [review]
Elevated plasma PLTP activity may predict an increased risk of T2DM in men
High systemic PLTP expression does not contribute significantly to a renal phenotype despite being implicated in systemic atherosclerosis in ApoE (show APOE Antibodies) deficient mice.
proteolytic cleavage of PLTP by cathepsin G (show CTSG Antibodies) may enhance the injurious inflammatory responses that occur in COPD (show ARCN1 Antibodies)
PLTP is actively involved in lipid transfer, cholesterol efflux, HDL (show HSD11B1 Antibodies) genesis, and remodeling at the blood-brain barrier.
Lower plasma CETP (show CETP Antibodies) or higher PLTP activity was each associated with a significantly increased risk of cardiovascular disease.
these findings elucidated that PLTP repressed LPS (show TLR4 Antibodies) induced inflammation due to extracellular LPS (show TLR4 Antibodies) binding capability, and the protective effects were not related to HDL (show HSD11B1 Antibodies) pool size in mice.
Data presented a novel model to link phospholipid metabolism to APP (show APP Antibodies) processing and also suggested that PLTP played an important role in Abeta (show APP Antibodies) metabolism and would be useful to further elucidate functions of PLTP in Alzheimer's disease susceptibility.
In hepatocytes, initial recruitment of phospholipid (PL) by apoB (show APOB Antibodies):1000 leading to the formation of the PL-rich apoB (show APOB Antibodies)-containing initiation complex is mediated to a large extent by PLTP.
PLTP plays an important role in modulating the stability of atherosclerotic plaques. The receptor-interacting protein 3 (show RIPK3 Antibodies)- reactive oxygen species signal pathway could be involved in this PLTP-mediated process.
Adipocyte PLTP plays a small but significant role in plasma PLTP activity and promotes cholesterol efflux from adipose tissues.
PLTP exerts significant effects on apoA-I (show APOA1 Antibodies) lipidation and nascent HDL (show HSD11B1 Antibodies) biogenesis in hepatocytes by promoting ATP-binding cassette transporter A1 (show ABCA1 Antibodies)-mediated lipid efflux and the remodeling of nascent HDL (show HSD11B1 Antibodies) particles.
Plasma Sphingosine-1-phosphate contents were decreased by 60.1 % in PLTP knockout mice (PLTP-/-, N = 5) compared with their wild type littermates (WT, N = 5) (151.70 +/- 38.59 vs. 379.32 +/- 59.90 nmol/l, P<0.01).
Therefore we concluded that PLTP deficiency impaired cognition and aggravated AD by enhancing the generation of Abeta (show APP Antibodies) in the cortex of old mice.
Cerebrovascular oxidative stress increased in PLTP deficient mice, including increased levels of reactive oxygen species (ROS) and lipid peroxidation marker 4-hydroxy-2-nonenal (HNE) and reduced superoxide dismutase (SOD) activity.
Results suggest that phospholipid transfer protein (PLTP) polymorphisms might be an important genetic influence on economic traits in Hanwoo (Korean cattle).
The protein encoded by this gene is one of at least two lipid transfer proteins found in human plasma. The encoded protein transfers phospholipids from triglyceride-rich lipoproteins to high density lipoprotein (HDL). In addition to regulating the size of HDL particles, this protein may be involved in cholesterol metabolism. At least two transcript variants encoding different isoforms have been found for this gene.
phospholipid transfer protein
, BPI fold containing family E
, lipid transfer protein II
, plasma phospholipid transfer protein
, PLTP-like protein