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Phospholipid Transfer Protein Proteins (PLTP)

The protein encoded by PLTP is one of at least two lipid transfer proteins found in human plasma. Additionally we are shipping PLTP Antibodies (84) and PLTP Kits (40) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PLTP 5360 P55058
PLTP 18830 P55065
Rat PLTP PLTP 296371  
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Top PLTP Proteins at antibodies-online.com

Showing 8 out of 10 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Human Cells Human His tag 50 μg Log in to see 16 Days
$382.80
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
HOST_Escherichia coli (E. coli) Human GST tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
Yeast Human His tag 50 μg Log in to see 31 to 36 Days
$341.00
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 16 to 21 Days
$314.29
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

PLTP Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , ,
,
Mouse (Murine)

Top referenced PLTP Proteins

  1. Human PLTP Protein expressed in Human Cells - ABIN2004045 : Valenta, Bulgrien, Bonnet, Curtiss: Macrophage PLTP is atheroprotective in LDLr-deficient mice with systemic PLTP deficiency. in Journal of lipid research 2007 (PubMed)

  2. Human PLTP Protein expressed in Wheat germ - ABIN1315481 : Henderson, Leon, Wasan: Differences in human phospholipid transfer protein activity following incubation of Fungizone compared to lipid-based Amphotericin-B formulations in normolipidemic and hyperlipidemic plasma. in Drug development and industrial pharmacy 2009 (PubMed)

More Proteins for Phospholipid Transfer Protein (PLTP) Interaction Partners

Maize/Corn (Zea mays) Phospholipid Transfer Protein (PLTP) interaction partners

  1. identification and characterization of CaM (show CALM Proteins)-binding domain of non-specific lipid transfer proteins

Human Phospholipid Transfer Protein (PLTP) interaction partners

  1. a novel association between PLTPa and PON1 (show PON1 Proteins) activity

  2. The domain of apolipoprotein E4 required for PLTP activation resides within its amino-terminal 1-185 region.

  3. Elevated baseline plasma levels of PLTP are associated with an increased risk of long-term all-cause mortality in patients with diabetes and known or suspected coronary disease.

  4. This review summarizes the recent progresses made in the PLTP research field and focuses on the complexity of the implication of PLTP in obesity, insulin (show INS Proteins) resistance and type 2 diabetes mellitus. [review]

  5. Elevated plasma PLTP activity may predict an increased risk of T2DM in men

  6. High systemic PLTP expression does not contribute significantly to a renal phenotype despite being implicated in systemic atherosclerosis in ApoE (show APOE Proteins) deficient mice.

  7. proteolytic cleavage of PLTP by cathepsin G (show CTSG Proteins) may enhance the injurious inflammatory responses that occur in COPD (show ARCN1 Proteins)

  8. PLTP is actively involved in lipid transfer, cholesterol efflux, HDL (show HSD11B1 Proteins) genesis, and remodeling at the blood-brain barrier.

  9. Lower plasma CETP (show CETP Proteins) or higher PLTP activity was each associated with a significantly increased risk of cardiovascular disease.

  10. Higher PLTP activity is associated with depressed LV systolic function in a dose-dependent manner.

Mouse (Murine) Phospholipid Transfer Protein (PLTP) interaction partners

  1. Data presented a novel model to link phospholipid metabolism to APP (show APP Proteins) processing and also suggested that PLTP played an important role in Abeta (show APP Proteins) metabolism and would be useful to further elucidate functions of PLTP in Alzheimer's disease susceptibility.

  2. In hepatocytes, initial recruitment of phospholipid (PL) by apoB (show APOB Proteins):1000 leading to the formation of the PL-rich apoB (show APOB Proteins)-containing initiation complex is mediated to a large extent by PLTP.

  3. PLTP plays an important role in modulating the stability of atherosclerotic plaques. The receptor-interacting protein 3 (show RIPK3 Proteins)- reactive oxygen species signal pathway could be involved in this PLTP-mediated process.

  4. Adipocyte PLTP plays a small but significant role in plasma PLTP activity and promotes cholesterol efflux from adipose tissues.

  5. PLTP exerts significant effects on apoA-I (show APOA1 Proteins) lipidation and nascent HDL (show HSD11B1 Proteins) biogenesis in hepatocytes by promoting ATP-binding cassette transporter A1 (show ABCA1 Proteins)-mediated lipid efflux and the remodeling of nascent HDL (show HSD11B1 Proteins) particles.

  6. Plasma Sphingosine-1-phosphate contents were decreased by 60.1 % in PLTP knockout mice (PLTP-/-, N = 5) compared with their wild type littermates (WT, N = 5) (151.70 +/- 38.59 vs. 379.32 +/- 59.90 nmol/l, P<0.01).

  7. Therefore we concluded that PLTP deficiency impaired cognition and aggravated AD by enhancing the generation of Abeta (show APP Proteins) in the cortex of old mice.

  8. Cerebrovascular oxidative stress increased in PLTP deficient mice, including increased levels of reactive oxygen species (ROS) and lipid peroxidation marker 4-hydroxy-2-nonenal (HNE) and reduced superoxide dismutase (SOD) activity.

  9. PLTP is actively involved in lipid transfer, cholesterol efflux, HDL (show HSD11B1 Proteins) genesis, and remodeling at the blood-brain barrier.

  10. PLTP can play a significant role in the pathophysiology of abdominal aortic aneurysm.

Pig (Porcine) Phospholipid Transfer Protein (PLTP) interaction partners

  1. PLTP is actively involved in lipid transfer, cholesterol efflux, HDL (show HSD11B1 Proteins) genesis, and remodeling at the blood-brain barrier.

Cow (Bovine) Phospholipid Transfer Protein (PLTP) interaction partners

  1. Results suggest that phospholipid transfer protein (PLTP) polymorphisms might be an important genetic influence on economic traits in Hanwoo (Korean cattle).

PLTP Protein Profile

Protein Summary

The protein encoded by this gene is one of at least two lipid transfer proteins found in human plasma. The encoded protein transfers phospholipids from triglyceride-rich lipoproteins to high density lipoprotein (HDL). In addition to regulating the size of HDL particles, this protein may be involved in cholesterol metabolism. At least two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with PLTP

  • phospholipid transfer protein (PLTP)
  • phospholipid transfer protein (pltp)
  • phospholipid transfer protein (LOC542343)
  • phospholipid transfer protein (Pltp)
  • Bpife protein
  • DKFZp469A1437 protein
  • HDLCQ9 protein
  • MGC84445 protein
  • OD107 protein
  • PLTP protein
  • zgc:100903 protein

Protein level used designations for PLTP

phospholipid transfer protein , BPI fold containing family E , lipid transfer protein II , plasma phospholipid transfer protein , PLTP-like protein

GENE ID SPECIES
100056507 Equus caballus
445125 Danio rerio
447591 Xenopus laevis
458291 Pan troglodytes
542343 Zea mays
549505 Xenopus (Silurana) tropicalis
100174348 Pongo abelii
5360 Homo sapiens
18830 Mus musculus
296371 Rattus norvegicus
100008882 Oryctolagus cuniculus
100720780 Cavia porcellus
397527 Sus scrofa
485903 Canis lupus familiaris
505640 Bos taurus
428164 Gallus gallus
101115982 Ovis aries
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