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anti-Pirin (PIR) Antibodies

PIR encodes a member of the cupin superfamily. Additionally we are shipping Pirin Kits (29) and Pirin Proteins (9) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PIR 69656 Q9D711
PIR 8544 O00625
PIR 363465 Q5M827
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Top anti-Pirin Antibodies at antibodies-online.com

Showing 10 out of 47 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Goat Un-conjugated ELISA, WB ABIN185265 (0.3µg/ml) staining of Human Heart lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-PIR Antibody Titration: 1.25ug/mlPositive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-PIR Antibody Titration: 1.25ug/mlPositive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Goat Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 8 to 10 Days
$493.17
Details
Human Rabbit Un-conjugated IHC, WB 100 μg Log in to see 8 to 10 Days
$493.17
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Mouse Un-conjugated DB, FACS, IP, WB HeLa cells were fixed in 2% paraformaldehyde/PBS and then permeabilized in 90% methanol. Cells were stained with anti-PIR mAb (shaded) or isotype control (unshaded) followed by Alexa Fluor 488 conjugated goat anti-mouse IgG. 50 μg Log in to see 7 to 9 Days
$285.71
Details
Dog Rabbit Un-conjugated IHC, ELISA, WB 100 μg Log in to see 2 to 3 Days
$343.75
Details
Human Rabbit Un-conjugated ELISA, WB 100 μg Log in to see 2 to 3 Days
$343.75
Details

PIR Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine)
,

Human
, , ,
,
, , , , ,
Rat (Rattus)
,

Top referenced anti-Pirin Antibodies

  1. Human Polyclonal PIR Primary Antibody for WB - ABIN374451 : Parada, Reis, Pinto, Sereno, Xavier-Cunha, Neto, Rocha-Pereira, Mota, Figueiredo, Teixeira: Chemopreventive Efficacy of Atorvastatin against Nitrosamine-Induced Rat Bladder Cancer: Antioxidant, Anti-Proliferative and Anti-Inflammatory Properties. in International journal of molecular sciences 2012 (PubMed)
    Show all 2 references for ABIN374451

  2. Human Polyclonal PIR Primary Antibody for ELISA, WB - ABIN185265 : Wendler, Kremmer, Förster, Winnacker: Identification of pirin, a novel highly conserved nuclear protein. in The Journal of biological chemistry 1997 (PubMed)

  3. Cow (Bovine) Polyclonal PIR Primary Antibody for IHC, WB - ABIN2778062 : Adams, Jia: Structural and biochemical analysis reveal pirins to possess quercetinase activity. in The Journal of biological chemistry 2005 (PubMed)

More Antibodies against Pirin Interaction Partners

Mouse (Murine) Pirin (PIR) interaction partners

  1. Sod1(-/-) mice have a significantly elevated level of Pir mRNA in the spleen and kidney but not in the liver, heart, or/and brain.

Arabidopsis thaliana Pirin (PIR) interaction partners

  1. PRN1 may play a critical role in cellular quercetin levels and influence light- or hormonal-directed early development.

  2. Arabidopsis mutants of the PRN1 gene, which is involved in abiotic and biotic signaling affecting phenylalanine-derived flavonoids, showed altered susceptibility to cryptoccocal infections, suggesting roles for this pathway in cryptococcal defense.

Human Pirin (PIR) interaction partners

  1. Pirin regulates E-cadherin (show CDH1 Antibodies) independently of Bcl3 (show BCL3 Antibodies)-Slug (show SNAI2 Antibodies) signaling.

  2. The NRF2 transcription factor binds to this element in vivo and drives the basal PIR expression.

  3. Pirin is a newly identified binding partner of EAF2/U19 (show EAF2 Antibodies) capable of down-regulating EAF2/U19 (show EAF2 Antibodies) protein and alleviating its inhibition of prostate cancer cell survival/proliferation.

  4. Data indicate that the R-shaped area composes the interface for pirin-NF-kappaB (show NFKB1 Antibodies) binding that is responsible for modulation of NF-kappaB's DNA-binding properties.

  5. pirin may have a relevant role in melanoma progression.

  6. knockdown of pirin or treatment with the small molecule inhibited melanoma cell migration

  7. This study aimed to examine genetic variations in the PIR gene by a comprehensive tagging method and its sex-specific effects on bone mineral density and osteoporotic risk.

  8. An abnormal pattern of PIR sub-cellular localization is a characteristic feature of a subset of melanomas, and suggest it may represent a marker associated with disease progression.

  9. Pirin downregulation is a feature of acute myeloid leukemia (show BCL11A Antibodies) and leads to impairment of terminal myeloid differentiation.

  10. x-ray crystallography of of human pirin shows that it is an iron-binding nuclear protein and transcription cofactor

Pirin (PIR) Antigen Profile

Protein Summary

This gene encodes a member of the cupin superfamily. The encoded protein is an Fe(II)-containing nuclear protein expressed in all tissues of the body and concentrated within dot-like subnuclear structures. Interactions with nuclear factor I/CCAAT box transcription factor as well as B cell lymphoma 3-encoded oncoprotein suggest the encoded protein may act as a transcriptional cofactor and be involved in the regulation of DNA transcription and replication. Alternatively spliced transcript variants have been described.

Gene names and symbols associated with anti-Pirin (PIR) Antibodies

  • pirin-like protein (pirin) antibody
  • pirin, quercetinase (pirin) antibody
  • pirin (Pir) antibody
  • pirin (pir) antibody
  • pirin (LOC100350592) antibody
  • pirin (PRN) antibody
  • pirin (iron-binding nuclear protein) (PIR) antibody
  • pirin (iron-binding nuclear protein) (Pir) antibody
  • pirin (iron-binding nuclear protein) (pir) antibody
  • pirin-like (LOC100514999) antibody
  • 2310042L19Rik antibody
  • ATPIRIN1 antibody
  • pirin antibody
  • Pirnl antibody
  • PRN1 antibody
  • xpir antibody
  • zgc:92778 antibody

Protein level used designations for anti-Pirin (PIR) Antibodies

pirin-like protein , pirin, quercetinase , iron-binding nuclear protein , pirin like , probable quercetin 2,3-dioxygenase PIR , probable quercetinase , pirin

GENE ID SPECIES
2772401 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130
8435992 Acetobacter pasteurianus IFO 3283-01
8436236 Acetobacter pasteurianus IFO 3283-01
69656 Mus musculus
436823 Danio rerio
100350592 Oryctolagus cuniculus
825091 Arabidopsis thaliana
8544 Homo sapiens
480846 Canis lupus familiaris
790878 Bos taurus
363465 Rattus norvegicus
379306 Xenopus laevis
100713331 Cavia porcellus
100514999 Sus scrofa
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