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anti-Pituitary Homeobox 3 (PITX3) Antibodies

PITX3 encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. Additionally we are shipping Pituitary Homeobox 3 Proteins (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PITX3 5309 O75364
PITX3 29609 P81062
PITX3 18742 O35160
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Top anti-Pituitary Homeobox 3 Antibodies at antibodies-online.com

Showing 10 out of 40 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-PITX3 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: HepG2 cell lysate WB Suggested Anti-PITX3  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:1562500  Positive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated ELISA, WB ABIN334461 (1µg/ml) staining of Human Cerebellum lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Goat Un-conjugated EIA, WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Chicken Rabbit Un-conjugated IHC, WB WB Suggested Anti-PITX3 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:12500Positive Control: MCF7 cell lysate Immunohistochemistry with Testis tissue at an antibody concentration of 5µg/ml using anti-PITX3 antibody (ARP33033_P050) 100 μL Log in to see 2 to 3 Days
$289.00
Details
Mouse Rabbit Un-conjugated IF, IHC (p), WB 50 μL Log in to see 6 to 8 Days
$500.50
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated IF, IHC, WB 0.05 mL Log in to see 2 to 3 Days
$481.25
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated IHC (p), WB Human Brain, Cerebellum (formalin-fixed, paraffin-embedded) stained with PITX3 antibody ABIN214803 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 8 to 10 Days
$676.50
Details

PITX3 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human ,
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Rat (Rattus) ,
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Mouse (Murine) ,
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Top referenced anti-Pituitary Homeobox 3 Antibodies

  1. Cow (Bovine) Polyclonal PITX3 Primary Antibody for WB - ABIN2780637 : Bidinost, Hernandez, Edward, Al-Rajhi, Lewis, Lupski, Stockton, Bejjani: Of mice and men: tyrosinase modification of congenital glaucoma in mice but not in humans. in Investigative ophthalmology & visual science 2006 (PubMed)
    Show all 2 references for ABIN2780637

  2. Human Polyclonal PITX3 Primary Antibody for EIA, WB - ABIN375225 : Kim, Inoue, Ishii, Vanti, Voronov, Murchison, Hannon, Abeliovich: A MicroRNA feedback circuit in midbrain dopamine neurons. in Science (New York, N.Y.) 2007 (PubMed)

More Antibodies against Pituitary Homeobox 3 Interaction Partners

Human Pituitary Homeobox 3 (PITX3) interaction partners

  1. novel PITX3 mutation c.573del, p.(Ser192Alafs*117), was identified in heterozygous state in a Belgo-Romanian family with a similar phenotype

  2. our data demonstrate that key midbrain dopamine regulators (Nurr1 (show NR4A2 Antibodies), Pitx3, and Lmx1a (show LMX1A Antibodies)) play overlapping as well as distinct roles during neurogenesis and neurotransmitter phenotype determination of mDA neurons

  3. Mutations in PITX3 are not a common cause or a risk factor for multisystem atrophy and progressive supranuclear palsy in the Polish population.

  4. Presence of the rs4919621 allele A in PITX3 significantly increases the risk of Parkinson's disease (PD) patients in a Caucasian population, while rs2281983 allele C and rs4919621 allele A were both risk factors in early onset PD.

  5. This study provided that NURR1 (show NR4A2 Antibodies) and PITX3 gene expression is decreased in the peripheral blood lymphocytes of Chinese patients with Parkinson's disease patients.

  6. novel synonymous SNP in PITX3 gene may contribute to PD risk in the Chinese population.

  7. Deletion of PITX3 is associated with aggressive neurobehavioral phenotype in Smith-Magenis Syndrome.

  8. Data show that BFSP2 (show BFSP2 Antibodies) and PITX3, hitherto known to cause eye defects only in a dominant fashion, can also present recessively.

  9. The results of this study suggested that these PITX3 SNPs do not contribute to the risk of developing PD in EOPD or LOPD in Chinese.

  10. The single nucleotide polymorphism rs3758549 (C >T substitution) in the Pitx3 gene is a potential risk for sporadic Parkinson disease (PD), especially early-onset PD in Chinese Han population.

Xenopus laevis Pituitary Homeobox 3 (PITX3) interaction partners

  1. In Xenopus, pitx3 appears to inhibit the rotation of presomitic cell cohorts and to be necessary to the bilaterally symmetric expression of pitx2 (show PITX2 Antibodies) in somites.

  2. Microarray-based identification of Pitx3 targets during Xenopus embryogenesis.

  3. expression of Pitx3 in the presumptive lens ectoderm is critical for retina development

Mouse (Murine) Pituitary Homeobox 3 (PITX3) interaction partners

  1. Pitx3 is specifically required for DA-related function and, if impaired, Pitx3 could contribute during the pathogenesis of Parkinson's disease.

  2. the sonic hedgehog (show SHH Antibodies) signaling pathway is both necessary and sufficient for the induction of ectopic PITX3 expression in chick mesencephalon downstream of WNT9A (show WNT9A Antibodies)-induced LMX1a (show LMX1A Antibodies) transcription.

  3. microphthalmos/aphakia inPITX3 nonsense mutant is caused by the expression of truncated PITX3, resulting in the abnormal expression of downstream targets and lens fiber proteins.

  4. Pitx3 binds to an evolutionary conserved bicoid-binding site on the 5'-upstream region of Foxe3 (show FOXE3 Antibodies). Pitx3 binding to 5'-upstream region of Foxe3 (show FOXE3 Antibodies) increased transcriptional activity significantly in a cell-based reporter assay.

  5. During fetal myogenesis, Pitx2 (show PITX2 Antibodies)/3 control this redox state through the regulation of Nrf1 (show NRF1 Antibodies) and of antioxidant pathways.

  6. Pitx3 overexpressing mouse significantly affects the gene expression of midbrain dopamine neurons. Motor coordination and locomotion activities are significantly affected in mice overexpressing Pitx3 mice.

  7. Primary fetal neurobehavioral deficit of the Pitx3 mutation is akinesia related to nigrostriatal damage.

  8. Two crucial mediators of mesodiencephalic dopaminergic neuronal development, En1 (show EN1 Antibodies) and Pitx3, interact in dopaminergic subset specification.

  9. a novel link between Pitx3 function and the selective pattern of midbrain dopaminergic neurons cell loss observed in Parkinson's disease.

  10. Reduced Th expression was associated with loss of Pitx3.

Zebrafish Pituitary Homeobox 3 (PITX3) interaction partners

  1. pitx3 expression in the primordia of the pituitary, lens, olfactory mucosa, and cranial ganglia is modulated by hedgehog (show SHH Antibodies) and nodal proteins' signaling.

  2. results demonstrate zebrafish pitx3 represents a true ortholog of the human PITX3 gene and the general function of the Pitx3 protein in lens development is conserved between mammals and the teleost fish

  3. Data demonstrate that Foxe3 (show FOXE3 Antibodies) is necessary for lens development in zebrafish and that foxe3 (show FOXE3 Antibodies) lies genetically downstream of pitx3 in a zebrafish lens development pathway.

  4. while lmx1b (show LMX1B Antibodies) paralogues may contribute to the generation of diencephalic dopaminergic precursors. Conversely, knock-down of pitx3 does not specifically affect any diencephalic dopamine cluster

Pituitary Homeobox 3 (PITX3) Antigen Profile

Protein Summary

This gene encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. Members of this family act as transcription factors. This protein is involved in lens formation during eye development. Mutations of this gene have been associated with anterior segment mesenchymal dysgenesis and congenital cataracts.

Gene names and symbols associated with PITX3

  • paired-like homeodomain 3 (PITX3) antibody
  • paired-like homeodomain 3 (Pitx3) antibody
  • paired-like homeodomain 3 (pitx3) antibody
  • paired-like homeodomain transcription factor 3 (Pitx3) antibody
  • paired-like homeodomain transcription factor 3 (pitx3) antibody
  • paired-like homeodomain transcription factor Pitx3 (pitx3) antibody
  • ak antibody
  • CTPP4 antibody
  • CTRCT11 antibody
  • pitx3 antibody
  • pitx3-A antibody
  • Ptx3 antibody
  • xPitx3 antibody
  • zgc:109716 antibody

Protein level used designations for PITX3

pituitary homeobox 3 , homeobox protein PITX3 , paired-like homeodomain transcription factor 3 , homeobox protein PTX3 , homeodomain transcription factor Pitx-3 , Pituitary homeobox 3 (Homeobox protein PITX3) , aphakia , bicoid-like homeodomain transcription factor 3 , bicoid-like homeodomain transcription factor Pitx3 , XPitx-3

GENE ID SPECIES
100422803 Ovis aries
5309 Homo sapiens
486856 Canis lupus familiaris
512000 Bos taurus
29609 Rattus norvegicus
398183 Xenopus laevis
423756 Gallus gallus
18742 Mus musculus
402974 Danio rerio
373824 Xenopus laevis
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