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Piwi-Like 2 (Drosophila) (PIWIL2) ELISA Kits

PIWIL2 belongs to the Argonaute family of proteins, which function in development and maintenance of germline stem cells (Sasaki et al., 2003 [PubMed 12906857]).[supplied by OMIM, Mar 2008].. Additionally we are shipping PIWIL2 Antibodies (62) and and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Mouse PIWIL2 PIWIL2 57746 Q8CDG1
Anti-Human PIWIL2 PIWIL2 55124 Q8TC59
Anti-Rat PIWIL2 PIWIL2 306011  
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More ELISA Kits for PIWIL2 Interaction Partners

Medaka Piwi-Like 2 (Drosophila) (PIWIL2) interaction partners

Zebrafish Piwi-Like 2 (Drosophila) (PIWIL2) interaction partners

  1. zili might have some effect on the formation of the ectoderm, mesoderm and endoderm during early embryogenesis

  2. Tdrd1 binds both zebrafish Piwi (show PIWIL1 ELISA Kits) proteins, Ziwi (show PIWIL1 ELISA Kits) and Zili, and reveals sequence specificity in the interaction between Tdrd1 tudor domains and symmetrically dimethylated arginines (sDMAs) in Zili.

  3. These results indicate that zili regulates dorsal-ventral patterning by antagonizing Bmp signaling during early embryogenesis in zebrafish.

  4. Zebrafish piwil2 is a mediator of Fgf signals in gastrula period.

  5. data presented show that Zili suppresses TGF-beta (show TGFB1 ELISA Kits) signaling by physically associating with Smad4 (show SMAD4 ELISA Kits) and preventing the formation of Smad2 (show SMAD2 ELISA Kits)/3/4 and Smad1 (show SMAD1 ELISA Kits)/5/9/4 complexes

  6. Ziwi (show PIWIL1 ELISA Kits) and Zili bind piRNAs of opposite polarity

Mouse (Murine) Piwi-Like 2 (Drosophila) (PIWIL2) interaction partners

  1. MILI is responsible for DNA methylation (show HELLS ELISA Kits) of a larger subset of TE families than MIWI2 (show PIWIL4 ELISA Kits).

  2. piRNA biogenesis triggered by PIWI slicing, and promoted by EXD1, ensures that the same guides instruct PIWI proteins in the nucleus and cytoplasm.

  3. Knockdown of MILI in B16 cell line could activate MAGEA expression and increase the cell migration ability, whereas the overexpression of MILI in B16BL6 cell line could inhibit MAGEA expression and decrease the cell migration ability.

  4. Report shows that fly Aub, Bombyx mori Siwi, and mouse MILI select targets bearing a t1A (show PDPN ELISA Kits) nucleotide irrespective of the identity of the g1 nucleotide of their piRNA guide.

  5. Mice with a global deletion of all three piwi (show PIWIL1 ELISA Kits) genes, Miwi (show PIWIL1 ELISA Kits), Mili, and Miwi2 (show PIWIL4 ELISA Kits), are able to maintain long-term hematopoiesis with no observable effect on the homeostatic hematopoietic stem cells compartment in adult mice.

  6. The in vitro studies show estrogen can downregulate the expression of miwi (show PIWIL1 ELISA Kits) and mili.

  7. characterize the genome-wide target RNA repertoire of Mili (Piwil2) and Miwi (Piwil1 (show PIWIL1 ELISA Kits)), two Piwi (show PIWIL1 ELISA Kits) proteins expressed in postnatal testis

  8. a new role for Piwil2 in DNA repair

  9. cycles of intra-Mili secondary piRNA biogenesis fuel piRNA amplification that is absolutely required for LINE1 silencing

  10. The results suggest broader roles for Piwil2 in genome surveillance beyond the germ line and a possible role in regulating the cell cycle of mesenchymal stem cells.

Human Piwi-Like 2 (Drosophila) (PIWIL2) interaction partners

  1. MMP9 (show MMP9 ELISA Kits) and PIWIL2 expression levels in cancerous tissues were significantly higher than the adjacent normal tissues

  2. PIWIL2 has a role in promoting progression of non-small cell lung cancer by inducing CDK2 (show CDK2 ELISA Kits) and Cyclin A (show CCNA2 ELISA Kits) expression

  3. Piwil 2 expression is correlated with disease-specific and progression-free survival of chemotherapy-treated bladder cancer patients

  4. Univariate analysis demonstrated that high PIWIL2 expression was associated with shorter survival time after radical resection.

  5. Knockdown of Piwil2 gene in SiHa cells inhibited cell growth and invasion, and downregulated matrix metalloproteinase-9 (MMP-9 (show MMP9 ELISA Kits)) compared to scrambled shRNA transfected cells

  6. Results show that both PIWIL2 protein isoforms are expressed in testicular germ cell lines but in the tumors, the short protein and mRNA are predominant and highly expressed in undifferentiated tumors.

  7. Our results indicate a reciprocal regulation between HIWI (show PIWIL1 ELISA Kits), HILI and some CSCs markers in colorectal cancer

  8. PIWIL2 modulates tumor cell proliferation and F-actin filaments by interacting with NME2 and regulating c-Myc (show MYC ELISA Kits) expression.

  9. This study revealed critical negative regulation of TGF-beta (show TGFB1 ELISA Kits) signalling by PIWIL2 in HepG2 tumour cells.

  10. Study indicates that Piwil2 plays a role in Fas (show FAS ELISA Kits)-mediated apoptosis and can affect p53 (show TP53 ELISA Kits) phosphorylation in tumor cells, revealing a novel mechanism of Piwil2 in apoptosis, and supports that Piwil2 plays an active role in tumorigenesis.

PIWIL2 Antigen Profile

Antigen Summary

PIWIL2 belongs to the Argonaute family of proteins, which function in development and maintenance of germline stem cells (Sasaki et al., 2003

Gene names and symbols associated with PIWIL2

  • piwi-like protein 2 (LOC100301588) antibody
  • piwi-like 2 (Drosophila) (piwil2) antibody
  • piwi-like RNA-mediated gene silencing 2 (Piwil2) antibody
  • piwi-like RNA-mediated gene silencing 2 (PIWIL2) antibody
  • piwil2 protein (rtili) antibody
  • CT80 antibody
  • HILI antibody
  • mili antibody
  • PIWIL1L antibody
  • piwil2 antibody
  • si:dkey-88f5.1 antibody
  • zili antibody

Protein level used designations for PIWIL2

piwi-like protein 2 , piwi like 2 , Miwi like , Miwi likw , piwi like homolog 2 , piwi-like homolog 2 , cancer/testis antigen 80 , piwi-like 2 , piwil2-like protein

100301588 Oryzias latipes
572134 Danio rerio
57746 Mus musculus
55124 Homo sapiens
306011 Rattus norvegicus
100135857 Oncorhynchus mykiss
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