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anti-Plasminogen Activator, Urokinase Receptor (PLAUR) Antibodies

PLAUR encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. Additionally we are shipping PLAUR Kits (60) and PLAUR Proteins (29) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PLAUR 18793 P35456
PLAUR 5329 Q03405
PLAUR 50692 P49616
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Top anti-PLAUR Antibodies at antibodies-online.com

Showing 10 out of 137 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Rat Rabbit Un-conjugated WB Western blot analysis of uPAR expression in rat kidney tissue lysate. 100 μg Log in to see 2 to 3 Days
$283.50
Details
Human Rabbit Un-conjugated WB 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-PLAUR AntibodyTitration: 1.0 µg/mL  Positive Control: HepG2 Whole Cell 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated IP, Neut, WB   100 μg Log in to see 2 to 3 Days
$336.00
Details
Human Rabbit Un-conjugated IHC (p), WB Anti-uPA Receptor antibody, Western blotting Lane 1: MCF-7 Cell Lysate Lane 2: HELA Cell Lysate Lane 3: RAJI Cell Lysate Lane 4: SMMC Cell Lysate Anti-uPA Receptor antibody, IHC(P) IHC(P): Human Mammary Cancer Tissue 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Rabbit Un-conjugated IHC (p), WB Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma Western blot analysis of PLAUR (arrow) using rabbit polyclonal PLAUR Antibody (W151) (ABIN652429). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the PLAUR gene. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse PE FACS 100 Tests Log in to see 10 to 12 Days
$277.20
Details
Human Mouse Un-conjugated FACS 100 μg Log in to see 10 to 12 Days
$103.27
Details
Human Rabbit Un-conjugated ICC, IF, WB WB Image uPAR antibody detects uPAR protein by western blot analysis. Various whole cell extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with uPAR antibody , diluted at 1:1000. ICC/IF Image uPAR antibody detects uPAR protein at cytoplasm by immunofluorescent analysis. Sample: A431 cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: uPAR protein stained by uPAR antibody , diluted at 1:500. Blue: Hoechst 33342 staining. 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Mouse PE FACS Flow cytometric analysis of Human UPAR(CD87) expression in Daudi cells. 50 Tests Log in to see 16 Days
$198.00
Details

PLAUR Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-PLAUR Antibodies

  1. Human Polyclonal PLAUR Primary Antibody for WB - ABIN1944762 : Roldan, Cubellis, Masucci, Behrendt, Lund, Danø, Appella, Blasi: Cloning and expression of the receptor for human urokinase plasminogen activator, a central molecule in cell surface, plasmin dependent proteolysis. in The EMBO journal 1990 (PubMed)
    Show all 5 references for ABIN1944762

  2. Human Monoclonal PLAUR Primary Antibody for FACS - ABIN2664853 : Beaufort, Leduc, Rousselle, Magdolen, Luther, Namane, Chignard, Pidard: Proteolytic regulation of the urokinase receptor/CD87 on monocytic cells by neutrophil elastase and cathepsin G. in Journal of immunology (Baltimore, Md. : 1950) 2003 (PubMed)
    Show all 4 references for ABIN2664853

  3. Human Monoclonal PLAUR Primary Antibody for FACS - ABIN2663624 : Tarui, Mazar, Cines, Takada: Urokinase-type plasminogen activator receptor (CD87) is a ligand for integrins and mediates cell-cell interaction. in The Journal of biological chemistry 2001 (PubMed)
    Show all 4 references for ABIN2663624

  4. Rat (Rattus) Polyclonal PLAUR Primary Antibody for WB - ABIN223401 : Viswanathan, Richardson, Togonu-Bickersteth, Dai, Liu, Vatsya, Sun, Yu, Munuswamy-Ramanujam, Baker, Lucas: Myxoma viral serpin, Serp-1, inhibits human monocyte adhesion through regulation of actin-binding protein filamin B. in Journal of leukocyte biology 2009 (PubMed)

More Antibodies against PLAUR Interaction Partners

Mouse (Murine) Plasminogen Activator, Urokinase Receptor (PLAUR) interaction partners

  1. Significance of the urokinase-type plasminogen activator (show PLAU Antibodies) and its receptor in the progression of focal segmental glomerulosclerosis in clinical and mouse models.

  2. Findings indicate a significant correlation of uPAR cleavage with breast cancer progression, but the precise biological consequence(s) of the cleavage or the cleavage products still remains to be elucidated.

  3. interaction of full-length suPAR with alphavbeta3 integrin expressed on podocytes results in down-modulation of nephrin (show NPHS1 Antibodies) that may affect kidney functionality in different human pathologies characterized by increased concentration of suPAR.

  4. In an (show EPHA3 Antibodies)in vivo murine angiogenesis model uPAR-deficient PTEN heterozygous animals incre (show PTEN Antibodies)ased the impaired angiogeni (show AKT1 Antibodies)c phenotype of uPAR knockout mice and were able to reverse the high invasive potential of PTEN heterozygotes.

  5. uPAR contributes to macrophage driven atherosclerotic lesion formation.

  6. we have firstly shown a fundamental mechanism of urokinase system(uPa (show PLAU Antibodies) and uPAR)-dependent regulation of the trajectory of growth and branching of blood vessels in early embryogenesis and in adults during the repair/regeneration of tissues.

  7. our data show that uPAR is required for efficient skin tumor formation

  8. Tumours with high levels of uPAR, as well as cells invading leiomyoma tissue with up-regulated uPAR expression, all displayed enhanced activity of gelatinolytic enzymes.

  9. deficiency of uPAR and PSMD6 (show PSMD6 Antibodies) delays DNA repair and leads to decreased cell survival.

  10. beta-elemene downregulates expression of uPA (show PLAU Antibodies), uPAR, MMP-2 (show MMP2 Antibodies), and MMP-9 (show MMP9 Antibodies) in a murine intraocular melanoma model

Human Plasminogen Activator, Urokinase Receptor (PLAUR) interaction partners

  1. This study examines the complexes of PAI-1 (show SERPINE1 Antibodies) with tissue-type and urokinase-type plasminogen activator (show PLAU Antibodies) and vitronectin (show VTN Antibodies) revealed by changes in the conformation and dynamics of the reactive center loop.

  2. results show that cleaved uPAR forms are significantly increased in patients with advanced prostate cancer.

  3. Hypoxia enhanced the endogenous uPAR mRNA and protein expression.HIF-1 protein bound the putative HIF-1 (show HIF1A Antibodies) response element on the uPAR promoter.uPAR protein expression was detected in cervical cancer but not in normal cervix or CIN (show PDXP Antibodies).

  4. Significance of the urokinase-type plasminogen activator (show PLAU Antibodies) and its receptor in the progression of focal segmental glomerulosclerosis in clinical and mouse models.

  5. uPAR/suPAR is elevated in most kidney diseases.

  6. The present paper develops a mathematical model of cancer recurrence besed on UPAR serum concentration.

  7. uPAR-VEGFR2 interaction is crucial for VEGF signaling in endothelial cells

  8. Human uPAR activation and its association with beta1-integrin are required for PDGF (show PDGFA Antibodies)-AB-induced migration.

  9. Both the depressed patients and suicide attempters had increased plasma soluble form of the urokinase receptor (suPAR). The levels of suPAR discriminated better between controls and suicide attempters than did C reactive protein (show CRP Antibodies).

  10. In HEK (show EPHA3 Antibodies) 293 cells, transfected with human uPAR, uPAR overexpression down-regulates PTEN (show PTEN Antibodies) and activates the PI3K (show PIK3CA Antibodies)/Akt (show AKT1 Antibodies)-pathway.

Cow (Bovine) Plasminogen Activator, Urokinase Receptor (PLAUR) interaction partners

  1. uPA (show PLAU Antibodies)/uPAR binding is involved in signaling pathways that activate transcription factors that regulate the synthesis of molecules concerned with the arrangement of a particular oviductal microenvironment.

  2. Data indicate that superoxide dismutase (SOD) inhibited high glucose (HG)-induced expression of uPAR and VEGF in bovine retinal microvascular endothelial cell (REC).

  3. These data indicated that E. coli LPS (show IRF6 Antibodies) led to an increase in u-PA (show PLAU Antibodies) activity and RNA expression of u-PA (show PLAU Antibodies) and u-PAR in BME-UV1 cells, thus strengthening the role of the PA system during pathological processes.

  4. the interaction between uPAR and Man-6-P/IGF2R (show IGF2R Antibodies) is a low percentage binding event and that suPAR and full-length uPAR bind the Man-6-P/IGF2R (show IGF2R Antibodies) by different mechanisms.

PLAUR Antigen Profile

Protein Summary

This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined.

Gene names and symbols associated with PLAUR

  • plasminogen activator, urokinase receptor (PLAUR) antibody
  • plasminogen activator, urokinase receptor (Plaur) antibody
  • urokinase-type plasminogen activator receptor (LOC100101584) antibody
  • CD87 antibody
  • Par antibody
  • PLAUR antibody
  • Plaur3 antibody
  • U-PAR antibody
  • UPAR antibody
  • uPAR-2 antibody
  • uPAR-3 antibody
  • URKR antibody

Protein level used designations for PLAUR

urokinase plasminogen activator surface receptor , plasminogen activator, urokinase receptor , urokinase plasminogen activator receptor , urokinase-type plasminogen activator receptor , monocyte activation antigen Mo3 , u-plasminogen activator receptor form 2 , urokinase-type plasminogen activator (uPA) receptor , U-PAR , uPAR , plasminogen activator urokinase receptor 3 , urinary plasminogen activator receptor 2 , urinary plasminogen activator receptor 3

GENE ID SPECIES
100033904 Equus caballus
100302564 Ovis aries
18793 Mus musculus
5329 Homo sapiens
476446 Canis lupus familiaris
281983 Bos taurus
50692 Rattus norvegicus
450103 Pan troglodytes
100101584 Oryctolagus cuniculus
Selected quality suppliers for anti-PLAUR (PLAUR) Antibodies
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