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anti-Plasminogen Activator, Urokinase Receptor (PLAUR) Antibodies

PLAUR encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. Additionally we are shipping PLAUR Kits (52) and PLAUR Proteins (30) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PLAUR 18793 P35456
PLAUR 5329 Q03405
PLAUR 50692 P49616
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Top anti-PLAUR Antibodies at antibodies-online.com

Showing 10 out of 167 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Rat Rabbit Un-conjugated WB Western blot analysis of uPAR expression in rat kidney tissue lysate. 100 μg Log in to see 2 to 3 Days
$283.50
Details
Human Rabbit Un-conjugated WB 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-PLAUR AntibodyTitration: 1.0 µg/mL  Positive Control: HepG2 Whole Cell 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated IP, Neut, WB   100 μg Log in to see 2 to 3 Days
$336.00
Details
Human Rabbit Un-conjugated IHC (p), WB Anti-uPA Receptor antibody, Western blotting Lane 1: MCF-7 Cell Lysate Lane 2: HELA Cell Lysate Lane 3: RAJI Cell Lysate Lane 4: SMMC Cell Lysate Anti-uPA Receptor antibody, IHC(P) IHC(P): Human Mammary Cancer Tissue 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Rabbit Un-conjugated IHC (p), WB Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma Western blot analysis of PLAUR (arrow) using rabbit polyclonal PLAUR Antibody (W151) (ABIN652429). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the PLAUR gene. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse PE FACS 100 Tests Log in to see 10 to 12 Days
$277.20
Details
Mouse Goat Biotin FACS, WB   50 μg Log in to see 6 to 7 Days
$505.31
Details
Human Mouse Un-conjugated FACS 100 μg Log in to see 10 to 12 Days
$103.27
Details
Human Rabbit Un-conjugated ICC, IF, WB WB Image uPAR antibody detects uPAR protein by western blot analysis. Various whole cell extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with uPAR antibody , diluted at 1:1000. ICC/IF Image uPAR antibody detects uPAR protein at cytoplasm by immunofluorescent analysis. Sample: A431 cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: uPAR protein stained by uPAR antibody , diluted at 1:500. Blue: Hoechst 33342 staining. 100 μL Log in to see 2 to 3 Days
$358.60
Details

PLAUR Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-PLAUR Antibodies

  1. Human Polyclonal PLAUR Primary Antibody for WB - ABIN1944762 : Roldan, Cubellis, Masucci, Behrendt, Lund, Danø, Appella, Blasi: Cloning and expression of the receptor for human urokinase plasminogen activator, a central molecule in cell surface, plasmin dependent proteolysis. in The EMBO journal 1990 (PubMed)
    Show all 5 references for ABIN1944762

  2. Human Monoclonal PLAUR Primary Antibody for FACS - ABIN2664853 : Beaufort, Leduc, Rousselle, Magdolen, Luther, Namane, Chignard, Pidard: Proteolytic regulation of the urokinase receptor/CD87 on monocytic cells by neutrophil elastase and cathepsin G. in Journal of immunology (Baltimore, Md. : 1950) 2003 (PubMed)
    Show all 4 references for ABIN2664853

  3. Human Monoclonal PLAUR Primary Antibody for FACS - ABIN2663624 : Tarui, Mazar, Cines, Takada: Urokinase-type plasminogen activator receptor (CD87) is a ligand for integrins and mediates cell-cell interaction. in The Journal of biological chemistry 2001 (PubMed)
    Show all 4 references for ABIN2663624

  4. Mouse (Murine) Polyclonal PLAUR Primary Antibody for FACS, WB - ABIN4900558 : van Zoelen, Florquin, de Beer, Pater, Verstege, Meijers, van der Poll: Urokinase plasminogen activator receptor-deficient mice demonstrate reduced hyperoxia-induced lung injury. in The American journal of pathology 2009 (PubMed)
    Show all 2 references for ABIN4900558

  5. Human Polyclonal PLAUR Primary Antibody for IP, Neut - ABIN223158 : Viswanathan, Richardson, Togonu-Bickersteth, Dai, Liu, Vatsya, Sun, Yu, Munuswamy-Ramanujam, Baker, Lucas: Myxoma viral serpin, Serp-1, inhibits human monocyte adhesion through regulation of actin-binding protein filamin B. in Journal of leukocyte biology 2009 (PubMed)

More Antibodies against PLAUR Interaction Partners

Mouse (Murine) Plasminogen Activator, Urokinase Receptor (PLAUR) interaction partners

  1. Significance of the urokinase-type plasminogen activator (show PLAU Antibodies) and its receptor in the progression of focal segmental glomerulosclerosis in clinical and mouse models.

  2. Findings indicate a significant correlation of uPAR cleavage with breast cancer progression, but the precise biological consequence(s) of the cleavage or the cleavage products still remains to be elucidated.

  3. interaction of full-length suPAR with alphavbeta3 integrin expressed on podocytes results in down-modulation of nephrin (show NPHS1 Antibodies) that may affect kidney functionality in different human pathologies characterized by increased concentration of suPAR.

  4. In an (show EPHA3 Antibodies)in vivo murine angiogenesis model uPAR-deficient PTEN heterozygous animals incre (show PTEN Antibodies)ased the impaired angiogeni (show AKT1 Antibodies)c phenotype of uPAR knockout mice and were able to reverse the high invasive potential of PTEN heterozygotes.

  5. uPAR contributes to macrophage driven atherosclerotic lesion formation.

  6. we have firstly shown a fundamental mechanism of urokinase system(uPa (show PLAU Antibodies) and uPAR)-dependent regulation of the trajectory of growth and branching of blood vessels in early embryogenesis and in adults during the repair/regeneration of tissues.

  7. our data show that uPAR is required for efficient skin tumor formation

  8. Tumours with high levels of uPAR, as well as cells invading leiomyoma tissue with up-regulated uPAR expression, all displayed enhanced activity of gelatinolytic enzymes.

  9. deficiency of uPAR and PSMD6 (show PSMD6 Antibodies) delays DNA repair and leads to decreased cell survival.

  10. beta-elemene downregulates expression of uPA (show PLAU Antibodies), uPAR, MMP-2 (show MMP2 Antibodies), and MMP-9 (show MMP9 Antibodies) in a murine intraocular melanoma model

Human Plasminogen Activator, Urokinase Receptor (PLAUR) interaction partners

  1. urokinase plasminogen activator receptor has a role in incidence of venous thromboembolism

  2. Our study implies that both soluble UPAR and advanced echocardiography are useful diagnostic tools for identifying patients with diabetes at risk of future clinical heart disease

  3. The effect of LIF (show LIF Antibodies) and uPAR on trophoblast migration and invasion was mediated by PI3K (show PIK3CA Antibodies)/AKT (show AKT1 Antibodies) signaling pathway.

  4. Soluble urokinase plasminogen (show PLG Antibodies) activation receptor (suPAR) is an emerging new biomarker for prognosticating cardiovascular disease

  5. we review the human and mouse Ly6/uPAR family gene and protein structure and genomic organization, expression, functions, and evolution, and introduce new names for novel family members

  6. Report presence of urokinase-type plasminogen activator receptor in seminal plasma, focusing on its interesting role as reliable and sensitive marker of inflammation for the differential diagnosis of male accessory gland inflammation.

  7. uPAR expression is higher in normal pregnant women than that in patients with threatened abortion. uPAR promotes trophoblast migration and invasion during embryo implantation as well as plays a role in trophoblast differentiation into syntrophoblasts.

  8. This study examines the complexes of PAI-1 (show SERPINE1 Antibodies) with tissue-type and urokinase-type plasminogen activator (show PLAU Antibodies) and vitronectin (show VTN Antibodies) revealed by changes in the conformation and dynamics of the reactive center loop.

  9. results show that cleaved uPAR forms are significantly increased in patients with advanced prostate cancer.

  10. Hypoxia enhanced the endogenous uPAR mRNA and protein expression.HIF-1 protein bound the putative HIF-1 (show HIF1A Antibodies) response element on the uPAR promoter.uPAR protein expression was detected in cervical cancer but not in normal cervix or CIN (show PDXP Antibodies).

Cow (Bovine) Plasminogen Activator, Urokinase Receptor (PLAUR) interaction partners

  1. Data show that urokinase-type plasminogen activator (uPA (show PLAU Antibodies)) is only expressed in the cumulus cells of immature and in vitro matured cumulus-oocyte complexes (COCs), while uPA (show PLAU Antibodies) receptor (uPAR) and plasminogen activator inhibitor-1 (PAI-1 (show SERPINE1 Antibodies)) are expressed in both the cumulus cells and the immature and in vitro matured oocytes.

  2. uPA (show PLAU Antibodies)/uPAR binding is involved in signaling pathways that activate transcription factors that regulate the synthesis of molecules concerned with the arrangement of a particular oviductal microenvironment.

  3. Data indicate that superoxide dismutase (SOD) inhibited high glucose (HG)-induced expression of uPAR and VEGF in bovine retinal microvascular endothelial cell (REC).

  4. These data indicated that E. coli LPS (show IRF6 Antibodies) led to an increase in u-PA (show PLAU Antibodies) activity and RNA expression of u-PA (show PLAU Antibodies) and u-PAR in BME-UV1 cells, thus strengthening the role of the PA system during pathological processes.

  5. the interaction between uPAR and Man-6-P/IGF2R (show IGF2R Antibodies) is a low percentage binding event and that suPAR and full-length uPAR bind the Man-6-P/IGF2R (show IGF2R Antibodies) by different mechanisms.

PLAUR Antigen Profile

Protein Summary

This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined.

Gene names and symbols associated with PLAUR

  • plasminogen activator, urokinase receptor (PLAUR) antibody
  • plasminogen activator, urokinase receptor (Plaur) antibody
  • urokinase-type plasminogen activator receptor (LOC100101584) antibody
  • CD87 antibody
  • Par antibody
  • PLAUR antibody
  • Plaur3 antibody
  • U-PAR antibody
  • UPAR antibody
  • uPAR-2 antibody
  • uPAR-3 antibody
  • URKR antibody

Protein level used designations for PLAUR

urokinase plasminogen activator surface receptor , plasminogen activator, urokinase receptor , urokinase plasminogen activator receptor , urokinase-type plasminogen activator receptor , monocyte activation antigen Mo3 , u-plasminogen activator receptor form 2 , urokinase-type plasminogen activator (uPA) receptor , U-PAR , uPAR , plasminogen activator urokinase receptor 3 , urinary plasminogen activator receptor 2 , urinary plasminogen activator receptor 3

GENE ID SPECIES
100033904 Equus caballus
100302564 Ovis aries
18793 Mus musculus
5329 Homo sapiens
476446 Canis lupus familiaris
281983 Bos taurus
50692 Rattus norvegicus
450103 Pan troglodytes
100101584 Oryctolagus cuniculus
Selected quality suppliers for anti-PLAUR (PLAUR) Antibodies
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