anti-Plastin 3 (PLS3) Antibodies

Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. Additionally we are shipping Plastin 3 Proteins (14) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PLS3 5358 P13797
PLS3 81748  
PLS3 102866 Q99K51
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Top anti-Plastin 3 Antibodies at antibodies-online.com

Showing 10 out of 61 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB <b>WB Suggested Anti-PLS3 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:62500<br><b>Positive Control: </b>HT1080 cell lysate WB Suggested Anti-PLS3 <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.2500 <br /> Positive Control: HT1080 cell lysate <br /> PLS3 is supported by BioGPS gene expression data to be expressed in HT1080 100 μL Log in to see 2 to 3 Days
$289.00
Details
Bat Rabbit Un-conjugated IHC (p), WB 50 μg Log in to see 7 to 9 Days
$676.50
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Antigen: 0.2 µg/100 µL  Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000;  Secondary: HRP conjugated Goat-Anti-Rabbit IgG at 1: 5000; TMB staining; Read the data in MicroplateReader by 450 Formalin-fixed and paraffin embedded rat cardiac muscle labeled with Rabbit Anti PLASTIN3/T Plastin Polyclonal Antibody, Unconjugated (ABIN702010) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$295.90
Details
Human Rabbit Un-conjugated ICC, IF, IHC (p), WB ICC/IF Image T-Plastin antibody detects T-Plastin protein at cytoplasm and nucleus by immunofluorescent analysis. Sample: HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: T-Plastin protein stained by T-Plastin antibody , diluted at 1:100. Red: alpha Tubulin, a cytoskeleton marker, stained by alpha Tubulin antibody [GT114] , diluted at 1:500. Blue: Hoechst 33342 staining. WB Image Sample (30 ug of whole cell lysate) A: NIH-3T3 B: JC C: BCL-1 7.5% SDS PAGE antibody diluted at 1:1000 100 μL Log in to see 1 to 2 Days
$358.60
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB Western Blot: T Plastin Antibody [NBP1-32380] - Sample(30 ug whole cell lysate)A:HeLa S3 B:Raji 7. 5% SDS PAGE, antibody diluted at 1:500. Western Blot: T Plastin Antibody [NBP1-32380] - Sample (30 ug of whole cell lysate) A: NIH-3T3 B: JC C: BCL-1 7. 5% SDS PAGE; antibody diluted at 1:1000. 0.1 mL Log in to see 7 to 9 Days
$447.56
Details
Human Rabbit Alexa Fluor 594 IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details
Human Rabbit Cy3 IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details
Human Rabbit Cy5.5 IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details
Human Rabbit Cy5 IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details
Human Rabbit Cy7 IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details

PLS3 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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More Antibodies against Plastin 3 Interaction Partners

Human Plastin 3 (PLS3) interaction partners

  1. PLS3 mutation plays a role in low turnover osteoporosis pathophysiology.

  2. In this study, the authors found that the actin filament bundling abilities of PLS1 (show PLS1 Antibodies) and PLS2 (show LCP1 Antibodies) were similarly sensitive to Ca(2 (show CA2 Antibodies)+) (pCa50 ~6.4), whereas PLS3 was less sensitive (pCa50 ~5.9).

  3. Patients with PLS3 mutation-related osteoporosis respond to teriparatide treatment.

  4. We show that genes of the classical apoptosis pathway are involved in the smn-1 (show SMN1 Antibodies)-mediated neuronal death, and that this phenotype can be rescued by the expression of human SMN1 (show SMN1 Antibodies), indicating a functional conservation between the two orthologs. Finally, we determined that Plastin3/plst-1 genetically interacts with smn-1 (show SMN1 Antibodies) to prevent degeneration, and that treatment with valproic acid is able to rescue the degenerative phenotype

  5. PLS3 expression does not always modify SMA (show SMN1 Antibodies) phenotype

  6. findings emphasize the power of genetic modifiers, PLS3 and CORO1C (show CORO1C Antibodies), to unravel the cellular pathomechanisms underlying spinal muscular atrophy (SMA (show SMN1 Antibodies))--and the power of combinatorial therapy based on splice correction of SMN2 (show SMN1 Antibodies) and endocytosis improvement to efficiently treat SMA (show SMN1 Antibodies)

  7. PLS3 is a genuine spinal muscular atrophy protective modifier in SMN1 (show SMN1 Antibodies)-deleted individuals

  8. Measurements of SMN (show STMN1 Antibodies) and PLS3 transcript and protein levels in induced pluripotent stem cell-derived motor neurons show limited value as Spinal muscular atrophy biomarkers.

  9. High levels of recombinant hPLS3 mRNA were expressed in motor neurons of SMA (show SMN1 Antibodies) mice and an increased level of PLS3 protein in total spinal cord, yet neither survival nor the fundamental electrophysiological aspects of the neuromuscular junction improved.

  10. results confirm the role of PLS3 mutations in early onset osteoporosis. The mechanism whereby PLS3 affects bone health is unclear, but it may be linked to osteocyte dendrite function and skeletal mechanosensing

Plastin 3 (PLS3) Antigen Profile

Protein Summary

Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). The C-terminal 570 amino acids of the T-plastin and L-plastin proteins are 83% identical. It contains a potential calcium-binding site near the N terminus. Alternate splicing results in multiple transcript variants.

Gene names and symbols associated with anti-Plastin 3 (PLS3) Antibodies

  • plastin 3 L homeolog (pls3.L) antibody
  • plastin 3 (PLS3) antibody
  • plastin 3 (pls3) antibody
  • plastin 3 (Pls3) antibody
  • plastin 3 (T-isoform) (Pls3) antibody
  • AI115446 antibody
  • AL024105 antibody
  • DKFZp459D0939 antibody
  • MGC68681 antibody
  • MGC106020 antibody
  • Plastin-3 antibody
  • PLS3 antibody
  • T-fimbrin antibody
  • T-plastin antibody

Protein level used designations for anti-Plastin 3 (PLS3) Antibodies

plastin 3 , plastin 3 (T isoform) , plastin-3 , plastin-3-like , T fimbrin , T plastin , T-plastin , plastin 3 (T-isoform) , plastin 3, T

GENE ID SPECIES
399002 Xenopus laevis
465817 Pan troglodytes
481025 Canis lupus familiaris
595091 Xenopus (Silurana) tropicalis
709055 Macaca mulatta
100053927 Equus caballus
100158187 Sus scrofa
100172754 Pongo abelii
100403677 Callithrix jacchus
100475279 Ailuropoda melanoleuca
100545275 Meleagris gallopavo
100602943 Nomascus leucogenys
5358 Homo sapiens
81748 Rattus norvegicus
505687 Bos taurus
102866 Mus musculus
100689375 Cricetulus griseus
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