Plastin 3 (PLS3) ELISA Kits

Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. Additionally we are shipping Plastin 3 Antibodies (60) and Plastin 3 Proteins (14) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human PLS3 PLS3 5358 P13797
Anti-Rat PLS3 PLS3 81748  
Anti-Mouse PLS3 PLS3 102866 Q99K51
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More ELISA Kits for Plastin 3 Interaction Partners

Human Plastin 3 (PLS3) interaction partners

  1. In this study, the authors found that the actin filament bundling abilities of PLS1 (show PLS1 ELISA Kits) and PLS2 (show LCP1 ELISA Kits) were similarly sensitive to Ca(2 (show CA2 ELISA Kits)+) (pCa50 ~6.4), whereas PLS3 was less sensitive (pCa50 ~5.9).

  2. Patients with PLS3 mutation-related osteoporosis respond to teriparatide treatment.

  3. We show that genes of the classical apoptosis pathway are involved in the smn-1 (show SMN1 ELISA Kits)-mediated neuronal death, and that this phenotype can be rescued by the expression of human SMN1 (show SMN1 ELISA Kits), indicating a functional conservation between the two orthologs. Finally, we determined that Plastin3/plst-1 genetically interacts with smn-1 (show SMN1 ELISA Kits) to prevent degeneration, and that treatment with valproic acid is able to rescue the degenerative phenotype

  4. PLS3 expression does not always modify SMA (show SMN1 ELISA Kits) phenotype

  5. findings emphasize the power of genetic modifiers, PLS3 and CORO1C (show CORO1C ELISA Kits), to unravel the cellular pathomechanisms underlying spinal muscular atrophy (SMA (show SMN1 ELISA Kits))--and the power of combinatorial therapy based on splice correction of SMN2 (show SMN1 ELISA Kits) and endocytosis improvement to efficiently treat SMA (show SMN1 ELISA Kits)

  6. PLS3 is a genuine spinal muscular atrophy protective modifier in SMN1 (show SMN1 ELISA Kits)-deleted individuals

  7. Measurements of SMN (show STMN1 ELISA Kits) and PLS3 transcript and protein levels in induced pluripotent stem cell-derived motor neurons show limited value as Spinal muscular atrophy biomarkers.

  8. High levels of recombinant hPLS3 mRNA were expressed in motor neurons of SMA (show SMN1 ELISA Kits) mice and an increased level of PLS3 protein in total spinal cord, yet neither survival nor the fundamental electrophysiological aspects of the neuromuscular junction improved.

  9. results confirm the role of PLS3 mutations in early onset osteoporosis. The mechanism whereby PLS3 affects bone health is unclear, but it may be linked to osteocyte dendrite function and skeletal mechanosensing

  10. plastin 3 is a regulator of actin microfilament bundles at the ES in which it dictates the configuration of the filamentous actin network

Plastin 3 (PLS3) Antigen Profile

Antigen Summary

Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). The C-terminal 570 amino acids of the T-plastin and L-plastin proteins are 83% identical. It contains a potential calcium-binding site near the N terminus. Alternate splicing results in multiple transcript variants.

Gene names and symbols associated with Plastin 3 (PLS3) ELISA Kits

  • plastin 3 (pls3) antibody
  • plastin 3 (PLS3) antibody
  • plastin 3 (T isoform) (pls3) antibody
  • plastin 3 (Pls3) antibody
  • plastin 3 (T-isoform) (Pls3) antibody
  • T-plastin (LOC100689375) antibody
  • AI115446 antibody
  • AL024105 antibody
  • DKFZp459D0939 antibody
  • MGC68681 antibody
  • MGC106020 antibody
  • Plastin-3 antibody
  • PLS3 antibody
  • T-fimbrin antibody
  • T-plastin antibody

Protein level used designations for Plastin 3 (PLS3) ELISA Kits

plastin 3 , plastin 3 (T isoform) , plastin-3 , plastin-3-like , T fimbrin , T plastin , T-plastin , plastin 3 (T-isoform) , plastin 3, T

GENE ID SPECIES
399002 Xenopus laevis
465817 Pan troglodytes
481025 Canis lupus familiaris
595091 Xenopus (Silurana) tropicalis
709055 Macaca mulatta
100053927 Equus caballus
100158187 Sus scrofa
100172754 Pongo abelii
100403677 Callithrix jacchus
100475279 Ailuropoda melanoleuca
100545275 Meleagris gallopavo
100602943 Nomascus leucogenys
5358 Homo sapiens
81748 Rattus norvegicus
505687 Bos taurus
102866 Mus musculus
100689375 Cricetulus griseus
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