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Platelet Endothelial Aggregation Receptor 1 Proteins (PEAR1)

PEAR1 is a platelet receptor that signals upon the formation of platelet-platelet contacts independent of platelet activation and secondary to platelet aggregation (Nanda et al., 2005 [PubMed 15851471]).[supplied by OMIM, Mar 2008].. Additionally we are shipping PEAR1 Antibodies (40) and PEAR1 Kits (2) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PEAR1 375033 Q5VY43
PEAR1 73182 Q8VIK5
PEAR1 295293  
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Top PEAR1 Proteins at antibodies-online.com

Showing 5 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 69 to 74 Days
$9,050.32
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 69 to 74 Days
$12,906.52
Details
HOST_Baculovirus infected Insect Cells Rat His tag 100 μg Log in to see 16 Days
$382.80
Details

PEAR1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine) ,
,
Rat (Rattus)

More Proteins for Platelet Endothelial Aggregation Receptor 1 (PEAR1) Interaction Partners

Human Platelet Endothelial Aggregation Receptor 1 (PEAR1) interaction partners

  1. Platelet endothelial aggregation receptor-1: a novel modifier of neoangiogenesis.

  2. Results suggest that genetic variation of PEAR1 is a significant determinant of endothelial function through pathways implicated in cardiovascular disease.

  3. FcepsilonRI (show FCER1G Proteins) alpha-chain (show FCGRT Proteins) is an activating platelet endothelium aggregation receptor 1 (PEAR1) ligand.

  4. genetic variability of GAS6 (show GAS6 Proteins) and PEAR1 genes may be associated with platelet hyperaggregability

  5. A common genetic variant in PEAR1 (rs12041331) reproducibly influenced platelet aggregation in aspirin-treated patients with coronary artery disease.

  6. study suggests that PEAR1 is not a hypertension susceptibility gene in humans.

  7. The SNPs in two regions of the PEAR1 gene, from rs3737224 to rs822442, and from rs1214331 to rs12566888, probably play important roles in prasugrel pharmacodynamics

  8. additional exonic variants in PEAR1 that may also determine variability in platelet aggregation, were identified.

  9. A-allele carriers of rs12041331 in the platelet endothelial aggregation receptor-1 (PEAR1) gene were more likely to experience a cardiovascular event or death compared with GG homozygotes

  10. PEAR1 attenuates megakaryopoiesis via control of the PI3K/PTEN pathway.

Mouse (Murine) Platelet Endothelial Aggregation Receptor 1 (PEAR1) interaction partners

  1. Platelet endothelial aggregation receptor-1: a novel modifier of neoangiogenesis.

  2. Jedi-1 signals through recruitment of GULP (show GULP1 Proteins), which promotes phagocytosis through a noncanonical phosphoclathrin-dependent mechanism.

  3. These results indicated that both Jedi-1 and MEGF10 (show MEGF10 Proteins) can mediate phagocytosis independently through the recruitment of Syk (show SYK Proteins).

  4. Jedi is involved in the fine regulation of the early stages of hematopoietic differentiation, presumably through the Notch (show NOTCH1 Proteins) signaling pathway.

  5. a cellular and molecular mechanism by which neuronal corpses are culled during dorsal root ganglia development involves Jedi protein

PEAR1 Protein Profile

Protein Summary

PEAR1 is a platelet receptor that signals upon the formation of platelet-platelet contacts independent of platelet activation and secondary to platelet aggregation (Nanda et al., 2005

Gene names and symbols associated with PEAR1

  • platelet endothelial aggregation receptor 1 (PEAR1)
  • platelet endothelial aggregation receptor 1 (pear1)
  • platelet endothelial aggregation receptor 1 (LOC100338327)
  • platelet endothelial aggregation receptor 1 (Pear1)
  • 3110045G13Rik protein
  • JEDI protein
  • Jedi-1 protein
  • Megf12 protein
  • RGD1305653 protein

Protein level used designations for PEAR1

platelet endothelial aggregation receptor 1 , multiple EGF-like-domains 12 , platelet endothelial aggregation receptor 1-like , hPEAR1 , multiple EGF-like domains protein 12 , multiple epidermal growth factor-like domains protein 12 , Jedi , jagged and Delta protein , mPEAR1 , protein Jedi

GENE ID SPECIES
457409 Pan troglodytes
490403 Canis lupus familiaris
571812 Danio rerio
718698 Macaca mulatta
787112 Bos taurus
100023818 Monodelphis domestica
100064623 Equus caballus
100338327 Oryctolagus cuniculus
100451525 Pongo abelii
100586891 Nomascus leucogenys
375033 Homo sapiens
73182 Mus musculus
295293 Rattus norvegicus
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